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Chalasani","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"NETHERLANDS","productType":"Vitamins\/Minerals\/Inorganic Salts","year":"2019","type":"Inapplicable","leadProduct":"Vitamin E","moa":"SEC14-like protein 4; SEC14-like protein 3; SEC14-like protein 2; Nuclear receptor subfamily 1 group I member 2; Protein kinase C beta type; Polyunsaturated fatty acid 5-lipoxygenase; Protein kinase C alpha type; Diacylglycerol kinase alpha; Serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform; Serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Royal DSM","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Royal DSM \/ Naga P. Chalasani","highestDevelopmentStatusID":"8","companyTruncated":"Royal DSM \/ Naga P. Chalasani"},{"orgOrder":0,"company":"Hovid BHD","sponsor":"Yuen Kah Hay","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"MALAYSIA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Tocotrienol","moa":"Undisclosed","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Hovid BHD","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hovid BHD \/ Yuen Kah Hay","highestDevelopmentStatusID":"8","companyTruncated":"Hovid BHD \/ Yuen Kah Hay"}]

Find Drugs for Hepatology (Liver, Pancreatic, Gall Bladder) in Phase II Clinical Development

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : SAR425899

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Study Phase : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : SAR425899 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          February 19, 2018

                          Lead Product(s) : SAR425899

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Pemvidutide is a Peptide drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Liver Diseases, Alcoholic.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          June 08, 2025

                          Lead Product(s) : Pemvidutide

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Shenzhen Third People's Hospital

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Shenzhen Third People's Hospital

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Lead Product(s) : AS1501

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Study Phase : Phase II

                          Sponsor : Guangzhou 8th People's Hospital | Shenzhen Zhongke Amshenn Pharmaceutical Co., Ltd.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : AS1501 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Acute-On-Chronic Liver Failure.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          April 08, 2025

                          Lead Product(s) : AS1501

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Guangzhou 8th People's Hospital | Shenzhen Zhongke Amshenn Pharmaceutical Co., Ltd.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : CM-101 (nebokitug) is a first-in-class dual activity monoclonal antibody that neutralizes CCL24, being evaluated for the treatment of primary sclerosing cholangitis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 27, 2025

                          Lead Product(s) : Nebokitug

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : CM-101 (nebokitug) is a first-in-class dual activity monoclonal antibody that neutralizes CCL24, being evaluated for the treatment of primary sclerosing cholangitis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          February 19, 2025

                          Lead Product(s) : Nebokitug

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : SHP626 (volixibat) is an IBAT inhibitor. It is currently being evaluated in the mid-stage clinical trial studies for treating Cholestatic Pruritus in Primary Biliary Cholangitis.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 10, 2024

                          Lead Product(s) : Volixibat

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : ALT-801 (pemvidutide) is a novel, investigational, peptide-based GLP-1/glucagon dual receptor agonist in development for the treatment of metabolic dysfunction-associated steatohepatitis.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          September 30, 2024

                          Lead Product(s) : Pemvidutide

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : The company intends to use the proceeds to fund its development programs for CM-101, a monoclonal antibody that neutralizes CCL24 activity, in patients with primary sclerosing cholangitis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          July 25, 2024

                          Lead Product(s) : Nebokitug

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : HBM Healthcare Investments

                          Deal Size : $10.0 million

                          Deal Type : Private Placement

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                          09

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : CM-101 is a first-in-class monoclonal antibody that neutralizes the soluble protein CCL24, which is under phase 2 clinical development for the treatment of primary sclerosing cholangitis (PSC).

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          July 25, 2024

                          Lead Product(s) : Nebokitug

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : RABI-767 is a novel, small molecule lipase inhibitor that halts the highly toxic cascade of fat necrosis, systemic toxicity, organ failure and mortality in severe acute pancreatitis.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 15, 2024

                          Lead Product(s) : RABI-767

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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