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Chalasani","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"NETHERLANDS","productType":"Vitamins\/Minerals\/Inorganic Salts","year":"2019","type":"Inapplicable","leadProduct":"Vitamin E","moa":"SEC14-like protein 4; SEC14-like protein 3; SEC14-like protein 2; Nuclear receptor subfamily 1 group I member 2; Protein kinase C beta type; Polyunsaturated fatty acid 5-lipoxygenase; Protein kinase C alpha type; Diacylglycerol kinase alpha; Serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform; Serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Royal DSM","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Royal DSM \/ Naga P. Chalasani","highestDevelopmentStatusID":"8","companyTruncated":"Royal DSM \/ Naga P. Chalasani"},{"orgOrder":0,"company":"Hovid BHD","sponsor":"Yuen Kah Hay","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"MALAYSIA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Tocotrienol","moa":"Undisclosed","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Hovid BHD","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hovid BHD \/ Yuen Kah Hay","highestDevelopmentStatusID":"8","companyTruncated":"Hovid BHD \/ Yuen Kah Hay"}]

    Find Drugs for Hepatology (Liver, Pancreatic, Gall Bladder) in Phase II Clinical Development

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                            01

                            Sanofi

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                            Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

                            Lead Product(s) : SAR425899

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Assessment of the Safety and Effect of SAR425899 Versus Placebo for the Treatment of Non-alcoholic Fatty Liver...

                            Details : SAR425899 is a Other Small Molecule drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Non-alcoholic Fatty Liver Disease.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            February 19, 2018

                            Lead Product(s) : SAR425899

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Altimmune

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                            Altimmune

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                            Lead Product(s) : Pemvidutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Pemvidutide Safety and Efficacy In Alcohol-Associated Liver Disease

                            Details : Pemvidutide is a Peptide drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Liver Diseases, Alcoholic.

                            Product Name : Undisclosed

                            Product Type : Peptide, Unconjugated

                            Upfront Cash : Inapplicable

                            June 08, 2025

                            Lead Product(s) : Pemvidutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Shenzhen Third People's Hospital

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                            Shenzhen Third People's Hospital

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                            ISPE Annual Meeting
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                            Lead Product(s) : AS1501

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Guangzhou 8th People's Hospital | Shenzhen Zhongke Amshenn Pharmaceutical Co., Ltd.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Chinese Phase II Trail of AS1501 in Acute-on-chronic Liver Failure (ACLF) Patients

                            Details : AS1501 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Acute-On-Chronic Liver Failure.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 08, 2025

                            Lead Product(s) : AS1501

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Guangzhou 8th People's Hospital | Shenzhen Zhongke Amshenn Pharmaceutical Co., Ltd.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            ChemomAb

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                            ISPE Annual Meeting
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                            ChemomAb

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                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Chemomab Shows Positive Phase 2 Nebokitug PSC Trial Results in Liver Biomarkers

                            Details : CM-101 (nebokitug) is a first-in-class dual activity monoclonal antibody that neutralizes CCL24, being evaluated for the treatment of primary sclerosing cholangitis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            March 27, 2025

                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            ChemomAb

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                            ISPE Annual Meeting
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                            ChemomAb

                            Israel arrow
                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Chemomab, FDA Align on Nebokitug Approval Path in PSC

                            Details : CM-101 (nebokitug) is a first-in-class dual activity monoclonal antibody that neutralizes CCL24, being evaluated for the treatment of primary sclerosing cholangitis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            February 19, 2025

                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Mirum Pharmaceuticals

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                            Mirum Pharmaceuticals

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                            Lead Product(s) : Volixibat

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Volixibat Granted Breakthrough Designation For Cholestatic Pruritus in PBC

                            Details : SHP626 (volixibat) is an IBAT inhibitor. It is currently being evaluated in the mid-stage clinical trial studies for treating Cholestatic Pruritus in Primary Biliary Cholangitis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 10, 2024

                            Lead Product(s) : Volixibat

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Altimmune

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                            Altimmune

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                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Pemvidutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Altimmune Completes Enrollment in Phase 2b IMPACT Trial of Pemvidutide for MASH

                            Details : ALT-801 (pemvidutide) is a novel, investigational, peptide-based GLP-1/glucagon dual receptor agonist in development for the treatment of metabolic dysfunction-associated steatohepatitis.

                            Product Name : Undisclosed

                            Product Type : Peptide, Unconjugated

                            Upfront Cash : Inapplicable

                            September 30, 2024

                            Lead Product(s) : Pemvidutide

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            ChemomAb

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                            ISPE Annual Meeting
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                            ChemomAb

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                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : HBM Healthcare Investments

                            Deal Size : $10.0 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            Chemomab Therapeutics Announces $10 Million Private Placement

                            Details : The company intends to use the proceeds to fund its development programs for CM-101, a monoclonal antibody that neutralizes CCL24 activity, in patients with primary sclerosing cholangitis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Undisclosed

                            July 25, 2024

                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : HBM Healthcare Investments

                            Deal Size : $10.0 million

                            Deal Type : Private Placement

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                            09

                            ChemomAb

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                            ISPE Annual Meeting
                            Not Confirmed

                            ChemomAb

                            Israel arrow
                            ISPE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Chemomab CM-101 Achieves Key Endpoints in Phase 2 for Primary Sclerosing Cholangitis

                            Details : CM-101 is a first-in-class monoclonal antibody that neutralizes the soluble protein CCL24, which is under phase 2 clinical development for the treatment of primary sclerosing cholangitis (PSC).

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            July 25, 2024

                            Lead Product(s) : Nebokitug

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Arrivo BioVentures

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                            Arrivo BioVentures

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                            Lead Product(s) : RABI-767

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Arrivo Gets FDA Fast Track for RABI-767 in Acute Pancreatitis

                            Details : RABI-767 is a novel, small molecule lipase inhibitor that halts the highly toxic cascade of fat necrosis, systemic toxicity, organ failure and mortality in severe acute pancreatitis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 15, 2024

                            Lead Product(s) : RABI-767

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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