[{"orgOrder":0,"company":"WuXi Biologics","sponsor":"Almirall","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"CHINA","productType":"Large molecule","date":"January 2020","year":"2020","type":"Collaboration","leadProduct":"Bispecific antibody","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"WuXi Biologics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"WuXi Biologics \/ Almirall, S.A","highestDevelopmentStatusID":"1","companyTruncated":"WuXi Biologics \/ Almirall, S.A"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Not Applicable","pharmaFlowCategory":"DU","upfrontCash":"Not Applicable","therapeuticArea":"Dermatology","country":"CANADA","productType":"Undisclosed","date":"January 2020","year":"2020","type":"Not Applicable","leadProduct":"TFC-1067","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Not Applicable"},{"orgOrder":0,"company":"Crescita Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","upfrontCash":"Not Applicable","therapeuticArea":"Dermatology","country":"CANADA","productType":"Small molecule","date":"January 2020","year":"2020","type":"Not Applicable","leadProduct":"Cannabinoid-based Product","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Crescita Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical","sponsorNew":"Crescita Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"Crescita Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Revance Therapeutics","sponsor":"Viatris","pharmaFlowCategory":"D","upfrontCash":"$25.0 million","therapeuticArea":"Dermatology","country":"","productType":"Large molecule","date":"June 2020","year":"2020","type":"Licensing Agreement","leadProduct":"OnabotulinumtoxinA","moa":"Ach release","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Revance Therapeutics","amount2":0.10000000000000001,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0.10000000000000001,"dosageForm":"Intramuscular Injection","sponsorNew":"Revance Therapeutics \/ Mylan","highestDevelopmentStatusID":"1","companyTruncated":"Revance Therapeutics \/ Mylan"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Not Applicable","pharmaFlowCategory":"DU","upfrontCash":"Not Applicable","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"June 2020","year":"2020","type":"Not Applicable","leadProduct":"Difluorocyclohexyloxyphenol","moa":"hTyr","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Not Applicable"},{"orgOrder":0,"company":"Applied Biology","sponsor":"Corpometria Institute","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"June 2020","year":"2020","type":"Collaboration","leadProduct":"Proxalutamide","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Applied Biology","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Applied Biology \/ Corpometria Institute","highestDevelopmentStatusID":"1","companyTruncated":"Applied Biology \/ Corpometria Institute"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Undisclosed","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"October 2020","year":"2020","type":"Agreement","leadProduct":"TFC-1067","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Undisclosed"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Not Applicable","pharmaFlowCategory":"DU","upfrontCash":"Not Applicable","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"October 2020","year":"2020","type":"Not Applicable","leadProduct":"TFC-1067","moa":"Tyrosinase activity","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Topical Cream","sponsorNew":"Sirona Biochem Corp \/ Not Applicable","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Not Applicable"},{"orgOrder":0,"company":"JT Pharmaceuticals","sponsor":"Titan Pharmaceuticals Inc","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Peptide","date":"October 2020","year":"2020","type":"Acquisition","leadProduct":"JT-09","moa":"Kappa opioid receptor","graph1":"Dermatology","graph2":"Undisclosed","graph3":"JT Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"JT Pharmaceuticals \/ Titan Pharmaceuticals","highestDevelopmentStatusID":"1","companyTruncated":"JT Pharmaceuticals \/ Titan Pharmaceuticals"},{"orgOrder":0,"company":"CollPlant","sponsor":"Allergan Aesthetics","pharmaFlowCategory":"D","upfrontCash":"$14.0 million","therapeuticArea":"Dermatology","country":"","productType":"Large molecule","date":"February 2021","year":"2021","type":"Collaboration","leadProduct":"rhCollagen","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"CollPlant","amount2":0.10000000000000001,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0.10000000000000001,"dosageForm":"Injection","sponsorNew":"CollPlant \/ Allergan","highestDevelopmentStatusID":"1","companyTruncated":"CollPlant \/ Allergan"},{"orgOrder":0,"company":"University of Virginia School of Medicine","sponsor":"Adial Pharmaceuticals","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Small molecule","date":"September 2021","year":"2021","type":"Collaboration","leadProduct":"Adenosine Analogs","moa":"Adenosine A2A receptor","graph1":"Dermatology","graph2":"Undisclosed","graph3":"University of Virginia School of Medicine","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"University of Virginia School of Medicine \/ Adial Pharmaceuticals","highestDevelopmentStatusID":"1","companyTruncated":"University of Virginia School of Medicine \/ Adial Pharmaceuticals"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"Allergan Aesthetics","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"June 2022","year":"2022","type":"Licensing Agreement","leadProduct":"Difluorocyclohexyloxyphenol","moa":"hTyr","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Sirona Biochem Corp \/ Allergan Aesthetics","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ Allergan Aesthetics"},{"orgOrder":0,"company":"Pressure BioSciences","sponsor":"QVC Skincare","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"December 2022","year":"2022","type":"Partnership","leadProduct":"Vitamin A","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Pressure BioSciences","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Pressure BioSciences \/ QVC Skincare","highestDevelopmentStatusID":"1","companyTruncated":"Pressure BioSciences \/ QVC Skincare"},{"orgOrder":0,"company":"Sirona Biochem Corp","sponsor":"RODAN & FIELDS LLC","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Small molecule","date":"January 2022","year":"2022","type":"Termination","leadProduct":"Difluorocyclohexyloxyphenol","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Sirona Biochem Corp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Cream","sponsorNew":"Sirona Biochem Corp \/ RODAN & FIELDS LLC","highestDevelopmentStatusID":"1","companyTruncated":"Sirona Biochem Corp \/ RODAN & FIELDS LLC"},{"orgOrder":0,"company":"Ingenza","sponsor":"Amplifica","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Undisclosed","date":"January 2023","year":"2023","type":"Collaboration","leadProduct":"Undisclosed","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Ingenza","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Ingenza \/ Amplifica","highestDevelopmentStatusID":"1","companyTruncated":"Ingenza \/ Amplifica"},{"orgOrder":0,"company":"Max Planck","sponsor":"Scinai Immunotherapeutics","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"GERMANY","productType":"Large molecule","date":"June 2023","year":"2023","type":"Licensing Agreement","leadProduct":"VHH-Antibody","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Max Planck","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Max Planck \/ BiondVax Pharmaceuticals","highestDevelopmentStatusID":"1","companyTruncated":"Max Planck \/ BiondVax Pharmaceuticals"},{"orgOrder":0,"company":"Avra","sponsor":"Springs Rejuvenation","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"U.S.A","productType":"Cell and Gene therapy","date":"December 2021","year":"2021","type":"Merger","leadProduct":"Stem Cell Therapy","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Avra","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Avra \/ Springs Rejuvenation","highestDevelopmentStatusID":"1","companyTruncated":"Avra \/ Springs Rejuvenation"},{"orgOrder":0,"company":"Topix Skin Health","sponsor":"University of Minnesota","pharmaFlowCategory":"D","upfrontCash":"Undisclosed","therapeuticArea":"Dermatology","country":"","productType":"Undisclosed","date":"June 2024","year":"2024","type":"Partnership","leadProduct":"ProteXidine","moa":"","graph1":"Dermatology","graph2":"Undisclosed","graph3":"Topix Skin Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Dermatology","amount2New":0,"dosageForm":"","sponsorNew":"Topix Skin Health \/ University of Minnesota","highestDevelopmentStatusID":"1","companyTruncated":"Topix Skin Health \/ University of Minnesota"}]

Find Novel Dermatology Drugs in Clinical Development

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                          Top Deals by Deal Size (USD bn)

                          01

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : The partnership aims to develop a proprietary molecule ProteXidine, a biomimetic decoy molecule that enhances the skin's innate ability to manage UV induced damage and inhibit the production of ROS.

                          Brand Name : ProteXidine

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 05, 2024

                          Lead Product(s) : ProteXidine

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : University of Minnesota

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          02

                          Max Planck

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          Max Planck

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          Details : The agreement aims to develop and commercialize VHH antibodies (NanoAbs) targeting Interleukin-17 (IL-17) as treatments for all potential indications, starting with psoriasis and psoriatic arthritis.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 05, 2023

                          Lead Product(s) : VHH-Antibody

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Scinai Immunotherapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : Amplifica has partnered with Ingenza to advance the development of its signalling molecules, which stimulate dormant hair follicle stem cells and result in the active regrowth of hairs, from proof of concept through toxicology and clinical trials.

                          Brand Name : Undisclosed

                          Molecule Type : Undisclosed

                          Upfront Cash : Undisclosed

                          January 20, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Amplifica

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : Retinol (and its derivative retinoate) is a form of Vitamin A used in multiple skincare products, such as lotions, creams, and serums. It has excellent antioxidant properties and is regarded as the number one anti-aging, wrinkle fighting, skin tightening...

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 07, 2022

                          Lead Product(s) : Vitamin A

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : QVC Skincare

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : Under Licensing agreement with Sirona, pursuant to which Allergan Aesthetics will develop and commercialize topical skin care treatments based on active ingredients derived from certain of Sirona’s patents for TFC-1067 (Difluorocyclohexyloxyphenol) and...

                          Brand Name : TFC-1067

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 13, 2022

                          Lead Product(s) : Difluorocyclohexyloxyphenol

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Allergan Aesthetics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : OliX, will deliver a focused company’s proprietary asymmetric siRNA technology and pipeline programs, including OLX104C for hair loss, OLX301A for wet/dry age-related macular degeneration, OLX702A for non-alcoholic steatohepatitis, and OLX703A for hepa...

                          Brand Name : OLX104C

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 07, 2022

                          Lead Product(s) : OLX104C

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : Under the terms of the agreement, Sirona will manufacture and supply TFC-1067 (difluorocyclohexyloxyphenol), a novel, new skin brightening ingredient, for use by Rodan + Fields on a non-exclusive basis and Rodan + Fields will launch a new product incorpo...

                          Brand Name : TFC-1067

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          January 16, 2022

                          Lead Product(s) : Difluorocyclohexyloxyphenol

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : RODAN & FIELDS LLC

                          Deal Size : Undisclosed

                          Deal Type : Termination

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                          08

                          Avra

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          Avra

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          Details : The combined entity will focus on stem cell therapy, facial rejuvenation, hair rejuvenation, non-surgical hair restoration, protein rich plasma (PRP) injections, and anti-aging treatments.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 20, 2021

                          Lead Product(s) : Stem Cell Therapy

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Springs Rejuvenation

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          09

                          University of Virginia School of Medicine

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          University of Virginia School of Medicine

                          Country arrow
                          Aquaexpo 2024
                          Not Confirmed

                          Details : Under the Agreement, Purnovate will supply lead adenosine compounds and research team will be responsible for evaluating these compounds for efficacy and determination of the ideal formulations for maximum absorption with the goal of initiating future cl...

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 28, 2021

                          Lead Product(s) : Adenosine Analogs

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Adial Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          Aquaexpo 2024
                          Not Confirmed
                          Aquaexpo 2024
                          Not Confirmed

                          Details : CollPlant has granted Allergan Aesthetics worldwide exclusivity to use its plant-derived recombinant human collagen (rhCollagen) in combination with Allergan Aesthetics' proprietary technologies, for the production and commercialization of dermal and sof...

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : $14.0 million

                          February 08, 2021

                          Lead Product(s) : rhCollagen

                          Therapeutic Area : Dermatology

                          Highest Development Status : Undisclosed

                          Sponsor : Allergan Aesthetics

                          Deal Size : $103.0 million

                          Deal Type : Collaboration

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