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Supplement","year":"2023","type":"Inapplicable","leadProduct":"VS002A","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"International Centre for Diarrhoeal Disease Research, Bangladesh","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Solution","sponsorNew":"International Centre for Diarrhoeal Disease Research, Bangladesh \/ Entrinsic Bioscience Inc.","highestDevelopmentStatusID":"1","companyTruncated":"International Centre for Diarrhoeal Disease Research, Bangladesh \/ Entrinsic Bioscience Inc."},{"orgOrder":0,"company":"Exosomm Ltd.","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Dietary Supplement","year":"2024","type":"Inapplicable","leadProduct":"Whey Protein Milk-Derived Extracellular Vesicle","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Exosomm Ltd.","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Exosomm Ltd. \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Exosomm Ltd. \/ Undisclosed"},{"orgOrder":0,"company":"Dairy Goat Co-operative (N.Z.) Limited","sponsor":"Chulalongkorn University","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"NEW ZEALAND","productType":"Dietary Supplement","year":"2022","type":"Inapplicable","leadProduct":"Whole Goat Milk","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Dairy Goat Co-operative (N.Z.) Limited","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Dairy Goat Co-operative (N.Z.) Limited \/ Chulalongkorn University","highestDevelopmentStatusID":"1","companyTruncated":"Dairy Goat Co-operative (N.Z.) Limited \/ Chulalongkorn University"},{"orgOrder":0,"company":"Inner Mongolia Yili Industrial Group Co., Ltd","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"CHINA","productType":"Undisclosed","year":"2012","type":"Inapplicable","leadProduct":"Yili Chang Qing Pro-Abb Yoghurt","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Inner Mongolia Yili Industrial Group Co., Ltd","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Inner Mongolia Yili Industrial Group Co., Ltd \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Inner Mongolia Yili Industrial Group Co., Ltd \/ Undisclosed"},{"orgOrder":0,"company":"Grupo de Investigaci\u00f3n Cl\u00ednica","sponsor":"Norgine","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"SPAIN","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"Ziverel","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Grupo de Investigaci\u00f3n Cl\u00ednica","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Grupo de Investigaci\u00f3n Cl\u00ednica \/ Norgine","highestDevelopmentStatusID":"1","companyTruncated":"Grupo de Investigaci\u00f3n Cl\u00ednica \/ Norgine"},{"orgOrder":0,"company":"Hadassah Medical Organization","sponsor":"Rambam Health Care Campus | Carmel Medical Center | Soroka University Medical Center | Tel Aviv Medical Center","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"ISRAEL","productType":"Miscellaneous","year":"2015","type":"Inapplicable","leadProduct":"Warfarin Sodium","moa":"Vitamin k epoxide reductase complex subunit 1 isoform 1","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Hadassah Medical Organization","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hadassah Medical Organization \/ Rambam Health Care Campus | Carmel Medical Center | Soroka University Medical Center | Tel Aviv Medical Center","highestDevelopmentStatusID":"1","companyTruncated":"Hadassah Medical Organization \/ Rambam Health Care Campus | Carmel Medical Center | Soroka University Medical Center | Tel Aviv Medical Center"},{"orgOrder":0,"company":"University Hospital T\u00fcbingen","sponsor":"SymbioPharm GmbH","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"GERMANY","productType":"Undisclosed","year":"2015","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"University Hospital T\u00fcbingen","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University Hospital T\u00fcbingen \/ SymbioPharm GmbH","highestDevelopmentStatusID":"1","companyTruncated":"University Hospital T\u00fcbingen \/ SymbioPharm GmbH"},{"orgOrder":0,"company":"Danisco","sponsor":"BioFortis","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"DENMARK","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Danisco","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Danisco \/ BioFortis","highestDevelopmentStatusID":"1","companyTruncated":"Danisco \/ BioFortis"},{"orgOrder":0,"company":"Novozymes","sponsor":"Analyze & Realize","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"DENMARK","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Novozymes","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Novozymes \/ Analyze & Realize","highestDevelopmentStatusID":"1","companyTruncated":"Novozymes \/ Analyze & Realize"},{"orgOrder":0,"company":"Hawthorne Effect Inc.","sponsor":"HLNatural, Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2019","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Hawthorne Effect Inc.","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hawthorne Effect Inc. \/ HLNatural, Inc.","highestDevelopmentStatusID":"1","companyTruncated":"Hawthorne Effect Inc. \/ HLNatural, Inc."},{"orgOrder":0,"company":"Radicle Science","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Radicle Science","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Radicle Science \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Radicle Science \/ Undisclosed"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2015","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NYU Langone Health \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"NYU Langone Health \/ Undisclosed"},{"orgOrder":0,"company":"Avexegen Therapeutics","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Avexegen Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Avexegen Therapeutics \/ National Institutes of Health","highestDevelopmentStatusID":"1","companyTruncated":"Avexegen Therapeutics \/ National Institutes of Health"},{"orgOrder":0,"company":"Atmo Biosciences Pty Ltd","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"AUSTRALIA","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Atmo Biosciences Pty Ltd","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Atmo Biosciences Pty Ltd \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Atmo Biosciences Pty Ltd \/ Undisclosed"},{"orgOrder":0,"company":"Enhanced Genomics","sponsor":"BGF","pharmaFlowCategory":"D","therapeuticArea":"Gastroenterology","country":"UNITED KINGDOM","productType":"Undisclosed","year":"2025","type":"Series A Financing","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Enhanced Genomics","amount2":0.02,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0.02,"dosageForm":"Undisclosed","sponsorNew":"Enhanced Genomics \/ BGF","highestDevelopmentStatusID":"1","companyTruncated":"Enhanced Genomics \/ BGF"},{"orgOrder":0,"company":"Wecare Probiotics Co., Ltd.","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"CHINA","productType":"Probiotic","year":"2025","type":"Inapplicable","leadProduct":"Probiotic","moa":"Immune","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Wecare Probiotics Co., Ltd.","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Serum","sponsorNew":"Wecare Probiotics Co., Ltd. \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Wecare Probiotics Co., Ltd. \/ Undisclosed"},{"orgOrder":0,"company":"Novozymes","sponsor":"Citruslabs","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"DENMARK","productType":"Probiotic","year":"2025","type":"Inapplicable","leadProduct":"Limosilactobacillus Reuteri Strain","moa":"Microbiome","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Novozymes","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Novozymes \/ Citruslabs","highestDevelopmentStatusID":"1","companyTruncated":"Novozymes \/ Citruslabs"},{"orgOrder":0,"company":"BioGaia Pharma","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"SWEDEN","productType":"Probiotic","year":"2025","type":"Inapplicable","leadProduct":"Limosilactobacillus Reuteri","moa":"Microbiome","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"BioGaia Pharma","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Drops","sponsorNew":"BioGaia Pharma \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"BioGaia Pharma \/ Undisclosed"},{"orgOrder":0,"company":"Biocodex","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"FRANCE","productType":"Probiotic","year":"2025","type":"Inapplicable","leadProduct":"Bacillus coagulans MY01","moa":"Microbiome","graph1":"Gastroenterology","graph2":"Undisclosed","graph3":"Biocodex","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"Biocodex \/ Undisclosed","highestDevelopmentStatusID":"1","companyTruncated":"Biocodex \/ Undisclosed"}]

Find Novel Gastroenterology Drugs in Clinical Development

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Capeserod

                          Therapeutic Area : Gastroenterology

                          Study Phase : Undisclosed

                          Sponsor : First Wave BioPharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Details : Under the terms of the agreement, First Wave will receive from Sanofi an exclusive, global license for Capeserod, a selective 5-HT4 receptor partial agonist, which First Wave will repurpose and develop for gastrointestinal (GI) indications.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          September 14, 2023

                          Lead Product(s) : Capeserod

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : First Wave BioPharma

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          02

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Bacillus coagulans MY01 is a Probiotic drug candidate, which is currently being evaluated in Undisclosed clinical studies for the treatment of Dyspepsia.

                          Product Name : Undisclosed

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          October 08, 2025

                          Lead Product(s) : Bacillus coagulans MY01

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Limosilactobacillus Reuteri is a Probiotic drug candidate, which is currently being evaluated in Undisclosed clinical studies for the treatment of Colic.

                          Product Name : Undisclosed

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          September 24, 2025

                          Lead Product(s) : Limosilactobacillus Reuteri

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Enhanced Genomics

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Enhanced Genomics

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : The funding will be used to expand Enhanced’s internal therapeutic pipeline in common diseases, including autoimmune conditions such as inflammatory bowel disease.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          September 16, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : BGF

                          Deal Size : $19.0 million

                          Deal Type : Series A Financing

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Limosilactobacillus Reuteri Strain is a Probiotic drug candidate, which is currently being evaluated in Undisclosed clinical studies for the treatment of Upper Gastrointestinal Discomfort.

                          Product Name : Undisclosed

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          September 09, 2025

                          Lead Product(s) : Limosilactobacillus Reuteri Strain

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Citruslabs

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Multivitamin is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in clinical studies for the treatment of Irritable Bowel Syndrome.

                          Product Name : Undisclosed

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          August 19, 2025

                          Lead Product(s) : Multivitamin

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Jiangsu Famous Medical Technology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Jiangsu Famous Medical Technology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Shenbai Granules

                          Therapeutic Area : Gastroenterology

                          Study Phase : Undisclosed

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University | First Affiliated Hospital of Harbin Medical University | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | The Second Affiliated Hospital of Chongqing Me

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Shenbai Granules is a Plant Extract/Herbal drug candidate, which is currently being evaluated in clinical studies for the treatment of Colorectal Adenoma.

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          August 19, 2025

                          Lead Product(s) : Shenbai Granules

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University | First Affiliated Hospital of Harbin Medical University | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | The Second Affiliated Hospital of Chongqing Me

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Radicle Science

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Radicle Science

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Gastrointestinal Diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          August 19, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Jiangsu Famous Medical Technology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Jiangsu Famous Medical Technology

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Lead Product(s) : Shenbai Granules

                          Therapeutic Area : Gastroenterology

                          Study Phase : Undisclosed

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University | The Second Hospital of Shandong University | Shengjing Hospital | Shenzhen Hospital of Southern Medical University | Sixth Affiliated Hospital, Sun Yat-sen University | Sichuan Provincial Peo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Shenbai Granules is a Plant Extract/Herbal drug candidate, which is currently being evaluated in clinical studies for the treatment of Colorectal Adenoma.

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          August 14, 2025

                          Lead Product(s) : Shenbai Granules

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : The First Affiliated Hospital with Nanjing Medical University | The Second Hospital of Shandong University | Shengjing Hospital | Shenzhen Hospital of Southern Medical University | Sixth Affiliated Hospital, Sun Yat-sen University | Sichuan Provincial Peo

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Asklepios Kliniken Hamburg

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Asklepios Kliniken Hamburg

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : Ropivacaine is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Ileus.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 01, 2025

                          Lead Product(s) : Ropivacaine Hydrochloride

                          Therapeutic Area : Gastroenterology

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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