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Biotechnology"},{"orgOrder":0,"company":"Ikarovec","sponsor":"UKi2S","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"UNITED KINGDOM","productType":"Undisclosed","year":"2020","type":"Funding","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Ikarovec","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Ikarovec \/ UKi2S","highestDevelopmentStatusID":"1","companyTruncated":"Ikarovec \/ UKi2S"},{"orgOrder":0,"company":"Pharmathen SA","sponsor":"Partners Group","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"GREECE","productType":"Undisclosed","year":"2021","type":"Acquisition","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Pharmathen SA","amount2":1.8999999999999999,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":1.8999999999999999,"dosageForm":"Undisclosed","sponsorNew":"Pharmathen SA \/ Partners Group","highestDevelopmentStatusID":"1","companyTruncated":"Pharmathen SA \/ Partners Group"},{"orgOrder":0,"company":"Wills Eye Hospital","sponsor":"Guardian Health Sciences, Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Glaucocetin","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Wills Eye Hospital","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Wills Eye Hospital \/ Guardian Health Sciences, Inc.","highestDevelopmentStatusID":"1","companyTruncated":"Wills Eye Hospital \/ Guardian Health Sciences, Inc."},{"orgOrder":0,"company":"Sight Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Tearcare System","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Sight Sciences","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Drops","sponsorNew":"Sight Sciences \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Sight Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Institut de la Macula y la Retina","sponsor":"Igen BioLab SLU","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Postbotic","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Institut de la Macula y la Retina","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Institut de la Macula y la Retina \/ Igen BioLab SLU","highestDevelopmentStatusID":"1","companyTruncated":"Institut de la Macula y la Retina \/ Igen BioLab SLU"},{"orgOrder":0,"company":"Nu Eyne Co., Ltd.","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Nu Eyne M02","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Nu Eyne Co., Ltd.","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Nu Eyne Co., Ltd. \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Nu Eyne Co., Ltd. \/ Inapplicable"},{"orgOrder":0,"company":"Abilion Medical Systems AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Walther System","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Abilion Medical Systems AB","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Abilion Medical Systems AB \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Abilion Medical Systems AB \/ Inapplicable"},{"orgOrder":0,"company":"Bruder Healthcare","sponsor":"CBCC Global","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Dry Eye Drink","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Bruder Healthcare","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Bruder Healthcare \/ CBCC Global","highestDevelopmentStatusID":"1","companyTruncated":"Bruder Healthcare \/ CBCC Global"},{"orgOrder":0,"company":"University of Miami","sponsor":"Florida Lions Eye Bank","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"Plasma Rich In Growth Factors","moa":"Growth factor","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"University of Miami","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Miami \/ Florida Lions Eye Bank","highestDevelopmentStatusID":"1","companyTruncated":"University of Miami \/ Florida Lions Eye Bank"},{"orgOrder":0,"company":"Essilor-Polylite Taiwan","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"Stellest Lenses","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Essilor-Polylite Taiwan","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Essilor-Polylite Taiwan \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Essilor-Polylite Taiwan \/ Inapplicable"},{"orgOrder":0,"company":"Irvine School of Medicine","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Controlled Substance","year":"2020","type":"Inapplicable","leadProduct":"Ketamine Hydrochloride","moa":"Glutamate [NMDA] receptor","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Irvine School of Medicine","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Irvine School of Medicine \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Irvine School of Medicine \/ Inapplicable"},{"orgOrder":0,"company":"ACRO Biomedical","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"TAIWAN","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"Collagen Ophthalmic Matrix","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"ACRO Biomedical","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ACRO Biomedical \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"ACRO Biomedical \/ Inapplicable"},{"orgOrder":0,"company":"Universit\u00e0 degli Studi 'G. d'Annunzio' Chieti e Pescara","sponsor":"OFFHEALTH S.p.A. | Universit\u00e0 degli Studi di Sassari | University of Pisa","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Nicotinamide","moa":"PARP1","graph1":"Ophthalmology","graph2":"Undisclosed","graph3":"Universit\u00e0 degli Studi 'G. d'Annunzio' Chieti e Pescara","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Universit\u00e0 degli Studi 'G. d'Annunzio' Chieti e Pescara \/ OFFHEALTH S.p.A. | Universit\u00e0 degli Studi di Sassari | University of Pisa","highestDevelopmentStatusID":"1","companyTruncated":"Universit\u00e0 degli Studi 'G. d'Annunzio' Chieti e Pescara \/ OFFHEALTH S.p.A. | Universit\u00e0 degli Studi di Sassari | University of Pisa"},{"orgOrder":0,"company":"Bio Nature 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GmbH","highestDevelopmentStatusID":"1","companyTruncated":"Palatin Technologies \/ Boehringer Ingelheim GmbH"}]

Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          April 21, 2022

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Study Phase : Undisclosed

                          Sponsor : Partners Group

                          Deal Size : $1,900.0 million

                          Deal Type : Acquisition

                          Details : Partners Group to Acquire Pharmathen, a Leading European Pharmaceutical Company, from BC Partners

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 19, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Partners Group

                          Deal Size : $1,900.0 million

                          Deal Type : Acquisition

                          Pharmathen

                          03

                          Istanbul Medipol University Hospital

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Istanbul Medipol University Hospital

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          August 29, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Varol TUNALI | Liv Hospital (Ulus)

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : The collaboration strengthens Boehringer’s innovative and diversified pipeline in retinal conditions and its underlying commitment to vision preservation and protection.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 18, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : $327.6 million

                          Deal Type : Collaboration

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                          05

                          Bio Nature Health

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Bio Nature Health

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Eye Empower is a Dietary Supplement drug candidate, which is currently being evaluated in clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          August 14, 2025

                          Lead Product(s) : Eye Empower

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Citruslabs

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Università degli Studi 'G. d'Annunzio' Chieti e Pescara

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Università degli Studi 'G. d'Annunzio' Chieti e Pescara

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Lead Product(s) : Nicotinamide

                          Therapeutic Area : Ophthalmology

                          Study Phase : Undisclosed

                          Sponsor : OFFHEALTH S.p.A. | Università degli Studi di Sassari | University of Pisa

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Nicotinamide is a Other Small Molecule drug candidate, which is currently being evaluated in clinical studies for the treatment of Glaucoma.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 05, 2025

                          Lead Product(s) : Nicotinamide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : OFFHEALTH S.p.A. | Università degli Studi di Sassari | University of Pisa

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Shih Chien Huang

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Shih Chien Huang

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          December 17, 2024

                          Lead Product(s) : Multicomponent Dietary Supplement

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Febico (Far East Bio-Tec Co Ltd)

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : Under the agreement terms, GC and Novelty will partner to jointly R&D antibody-based protein therapeutics for geographic atrophy, supporting all stages of the drug development lifecycle.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          October 28, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : Novelty Nobility

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          09

                          Ecolite Group

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Ecolite Group

                          Country arrow
                          ESCRS
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          August 28, 2024

                          Lead Product(s) : Twinkle Eyez

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : UCSI University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : The companies will work to develop SGN’s MNP platform-based Cyclosporine formulation for use with Eyenovia’s Optejet dispenser for treatment of chronic dry eye disease.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          July 30, 2024

                          Lead Product(s) : Cyclosporine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Undisclosed

                          Sponsor : SGN Nanopharma

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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