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    Chemistry

    Click the arrow to open the dropdown
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    read-moreClick the button for full data set
    Also known as:
    Molecular Formula
    C23H21F7N4O3
    Molecular Weight
    534.4  g/mol
    InChI Key
    ATALOFNDEOCMKK-OITMNORJSA-N
    Aprepitant
    1 2D Structure

    Aprepitant

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
    2.1.2 InChI
    InChI=1S/C23H21F7N4O3/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)37-20-19(13-2-4-17(24)5-3-13)34(6-7-36-20)11-18-31-21(35)33-32-18/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H2,31,32,33,35)/t12-,19+,20-/m1/s1
    2.1.3 InChI Key
    ATALOFNDEOCMKK-OITMNORJSA-N
    2.1.4 Canonical SMILES
    CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F
    2.1.5 Isomeric SMILES
    C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)NN3)C4=CC=C(C=C4)F
    2.2 Create Date
    2006-07-28
    3 Chemical and Physical Properties
    Molecular Weight 534.4 g/mol
    Molecular Formula C23H21F7N4O3
    XLogP34.2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count11
    Rotatable Bond Count6
    Exact Mass534.15018768 g/mol
    Monoisotopic Mass534.15018768 g/mol
    Topological Polar Surface Area75.2 A^2
    Heavy Atom Count37
    Formal Charge0
    Complexity810
    Isotope Atom Count0
    Defined Atom Stereocenter Count3
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameAprepitant
    PubMed HealthAprepitant (By mouth)
    Drug ClassesAntiemetic
    Drug LabelEMEND (aprepitant) is a substance P/neurokinin 1 (NK1) receptor antagonist, chemically described as 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Its empiric...
    Active IngredientAprepitant
    Dosage FormCapsule
    RouteOral
    Strength125mg; 80mg; 40mg
    Market StatusPrescription
    CompanySandoz

    2 of 4  
    Drug NameEmend
    PubMed HealthAprepitant (By mouth)
    Drug ClassesAntiemetic
    Drug LabelEMEND (aprepitant) is a substance P/neurokinin 1 (NK1) receptor antagonist, chemically described as 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Its empiric...
    Active IngredientAprepitant; Fosaprepitant dimeglumine
    Dosage FormCapsule; Powder
    RouteIntravenous; Oral
    Strengtheq 150mg base/vial; 125mg; 80mg; 40mg
    Market StatusPrescription
    CompanyMerck; Merck And

    3 of 4  
    Drug NameAprepitant
    PubMed HealthAprepitant (By mouth)
    Drug ClassesAntiemetic
    Drug LabelEMEND (aprepitant) is a substance P/neurokinin 1 (NK1) receptor antagonist, chemically described as 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Its empiric...
    Active IngredientAprepitant
    Dosage FormCapsule
    RouteOral
    Strength125mg; 80mg; 40mg
    Market StatusPrescription
    CompanySandoz

    4 of 4  
    Drug NameEmend
    PubMed HealthAprepitant (By mouth)
    Drug ClassesAntiemetic
    Drug LabelEMEND (aprepitant) is a substance P/neurokinin 1 (NK1) receptor antagonist, chemically described as 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one. Its empiric...
    Active IngredientAprepitant; Fosaprepitant dimeglumine
    Dosage FormCapsule; Powder
    RouteIntravenous; Oral
    Strengtheq 150mg base/vial; 125mg; 80mg; 40mg
    Market StatusPrescription
    CompanyMerck; Merck And

    API Reference Price

    read-more
    read-more
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D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"USP","supplierCountry":"INDIA","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.000015","unit":"KGS","unitRateFc":"53200000","totalValueFC":"824.9","currency":"USD","unitRateINR":"4191610667","date":"25-Mar-2022","totalValueINR":"62874.16","totalValueInUsd":"824.9","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"8003640","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1658946600,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1&3,AZAMABAD","city":"HYDERABAD,TELANGANA","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"NA","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"21.12","actualQuantity":"21120","unit":"GMS","unitRateFc":"21","totalValueFC":"463371.4","currency":"USD","unitRateINR":"1744.6","date":"28-Jul-2022","totalValueINR":"36845687.7","totalValueInUsd":"463371.4","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"9763716","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"18\/1&3,AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686681000,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1&3,AZAMABAD","city":"HYDERABAD,TELANGANA","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"NA","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"22.38","actualQuantity":"22380","unit":"GMS","unitRateFc":"21","totalValueFC":"476862.6","currency":"USD","unitRateINR":"1751.8","date":"14-Jun-2023","totalValueINR":"39196331.86","totalValueInUsd":"476862.6","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"18\/1&3,AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1689964200,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1&3,AZAMABAD","city":"HYDERABAD,TELANGANA","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"NA","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"21.02","actualQuantity":"21020","unit":"GMS","unitRateFc":"21","totalValueFC":"445504.3","currency":"USD","unitRateINR":"1741.8","date":"22-Jul-2023","totalValueINR":"36615788.66","totalValueInUsd":"445504.3","indian_port":"HYDERABAD AIR","hs_no":"29349990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"18\/1&3,AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698431400,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1 3 AZAMABAD","city":"HYDERABAD ,ANDHRA PRADESH","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"21.58","actualQuantity":"21580","unit":"GMS","unitRateFc":"19","totalValueFC":"423193.7","currency":"USD","unitRateINR":"1632.2","date":"28-Oct-2023","totalValueINR":"35222114.78","totalValueInUsd":"423193.7","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"8524013","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"1764 LITCHFIELD TURNPIKESUITE 202 WOODBRIDGE,CT, 06525 US","customerAddress":"18\/1 3 AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710527400,"product":"FOSAPREPITANT DIMEGLUMINE BATCH NO: 11222006&11220007 MFGDATE: 06\/2022 EXP DATE : 06\/2025","address":"PLOT No.30, GALAXY ,","city":"BENGALURU","supplier":"STERISCIENCE","supplierCountry":"UNITED STATES","foreign_port":"WASHINGTON, DULLES I","customer":"STERISCIENCE SPECIALTIES PRIVATE ","customerCountry":"INDIA","quantity":"5.51","actualQuantity":"5.513","unit":"KGS","unitRateFc":"22050","totalValueFC":"125279.4","currency":"USD","unitRateINR":"1886935.1","date":"16-Mar-2024","totalValueINR":"10402673.38","totalValueInUsd":"125279.4","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"2608915","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"36 ROBINSON ROAD68877SDNF SG","customerAddress":"PLOT No.30, GALAXY ,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710527400,"product":"FOSAPREPITANT DIMEGLUMINE BATCH NO: 11223010 MFGDATE: 11\/2023 EXP DATE : 07\/2026","address":"PLOT No.30, GALAXY ,","city":"BENGALURU","supplier":"STERISCIENCE","supplierCountry":"UNITED STATES","foreign_port":"WASHINGTON, DULLES I","customer":"STERISCIENCE SPECIALTIES PRIVATE ","customerCountry":"INDIA","quantity":"3.44","actualQuantity":"3.44","unit":"KGS","unitRateFc":"21000","totalValueFC":"74449.3","currency":"USD","unitRateINR":"1797081.1","date":"16-Mar-2024","totalValueINR":"6181958.91","totalValueInUsd":"74449.3","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"2608915","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"WASHINGTON, DULLES I","supplierAddress":"36 ROBINSON ROAD68877SDNF SG","customerAddress":"PLOT No.30, GALAXY ,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713551400,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1 3 AZAMABAD","city":"HYDERABAD ,ANDHRA PRADESH","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"15.92","actualQuantity":"15920","unit":"GMS","unitRateFc":"19","totalValueFC":"316031.1","currency":"USD","unitRateINR":"1657.7","date":"20-Apr-2024","totalValueINR":"26390903.76","totalValueInUsd":"316031.1","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"3125927","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"1764 LITCHFIELD TURNPIKESUITE 202 WOODBRIDGE,CT, 06525 US","customerAddress":"18\/1 3 AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722191400,"product":"FOSAPREPITANT DIMEGLUMINE","address":"18\/1 3 AZAMABAD","city":"HYDERABAD ,ANDHRA PRADESH","supplier":"CHEMWERTH INC","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"BIOLOGICAL E","customerCountry":"INDIA","quantity":"21.46","actualQuantity":"21460","unit":"GMS","unitRateFc":"19","totalValueFC":"419447.2","currency":"USD","unitRateINR":"1633.8","date":"29-Jul-2024","totalValueINR":"35062039.5","totalValueInUsd":"419447.2","indian_port":"Hyderabad Air","hs_no":"29349990","bill_no":"4769824","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"1764 LITCHFIELD TURNPIKESUITE 202 WOODBRIDGE,CT, 06525 US","customerAddress":"18\/1 3 AZAMABAD"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734460200,"product":"HISY-PMDA-I005-N PAMIDRONIC ACID LOT NO L00012410 HISY-FSPR-C047-N FOSAPREPITANT DIMEGLUMINE","address":"PLOT No.30, GALAXY ,","city":"BENGALURU","supplier":"CHEMWERTH INC","supplierCountry":"UNITED STATES","foreign_port":"NEW YORK - JOHN F. K","customer":"STERISCIENCE SPECIALTIES PRIVATE ","customerCountry":"INDIA","quantity":"2.50","actualQuantity":"2500","unit":"GMS","unitRateFc":"110.2","totalValueFC":"277808.9","currency":"USD","unitRateINR":"9442.1","date":"18-Dec-2024","totalValueINR":"23605140","totalValueInUsd":"277808.9","indian_port":"Bangalore Air","hs_no":"29349990","bill_no":"7320044","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK - JOHN F. K","supplierAddress":"1764 LITCHFIELD TURNPIKE SUITE 202 WOODBRIDGE SDNF US","customerAddress":"PLOT No.30, GALAXY ,"},{"dataSource":"API Import","activeIngredients":"","year":"2025","qtr":"Q1","strtotime":1740335400,"product":"REIMPORT OF FOSAPREPITANT DIMEGLUMINE (BATCH NOS. 802312292)(FOC)REIMPORT OF FOSAPREPITANT DIMEGLUMINE (BATCH NOS. 802312292)","address":"PLOT 170-172, CHANDRAMOULI,INDUSTR","city":"SOLAPUR,MAHARASHTRA","supplier":"TECNIMEDE","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"ALIVUS LIFE SCIENCES LIMITED","customerCountry":"INDIA","quantity":"1.09","actualQuantity":"1.086","unit":"KGS","unitRateFc":"18517.1","totalValueFC":"20291.3","currency":"N\/A","unitRateINR":"1624874.5","date":"24-Feb-2025","totalValueINR":"1764613.67","totalValueInUsd":"20291.3","indian_port":"Bombay Air","hs_no":"29339990","bill_no":"8531527","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"MEDICINAL,S.A., RUA DA TAPADA GRANDE 2,ABRUNHEIRA,PORTUGAL 2710-089 ,PORTUGAL, PORTUGAL","customerAddress":"PLOT 170-172, CHANDRAMOULI,INDUSTR"}]
    28-Jan-2021
    17-Mar-2025
    KGS
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    Average Price (USD/KGS)

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    API Imports and Exports

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    Australia

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    Apotex Pty Ltd

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    Aprepitant

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    Southern Cross Pharma Pty Ltd

    Australia
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    Australia
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    Aprepitant

    Brand Name : APREPITANT SCP

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    Southern Cross Pharma Pty Ltd

    Australia
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    ABOUT THIS PAGE

    Looking for / Aprepitant API manufacturers, exporters & distributors?

    Aprepitant manufacturers, exporters & distributors 1

    44

    PharmaCompass offers a list of Aprepitant API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Aprepitant manufacturer or Aprepitant supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Aprepitant manufacturer or Aprepitant supplier.

    PharmaCompass also assists you with knowing the Aprepitant API Price utilized in the formulation of products. Aprepitant API Price is not always fixed or binding as the Aprepitant Price is obtained through a variety of data sources. The Aprepitant Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Aprepitant

    Aprepitant Manufacturers

    A Aprepitant manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aprepitant, including repackagers and relabelers. The FDA regulates Aprepitant manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aprepitant API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Aprepitant manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Aprepitant Suppliers

    A Aprepitant supplier is an individual or a company that provides Aprepitant active pharmaceutical ingredient (API) or Aprepitant finished formulations upon request. The Aprepitant suppliers may include Aprepitant API manufacturers, exporters, distributors and traders.

    click here to find a list of Aprepitant suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Aprepitant USDMF

    A Aprepitant DMF (Drug Master File) is a document detailing the whole manufacturing process of Aprepitant active pharmaceutical ingredient (API) in detail. Different forms of Aprepitant DMFs exist exist since differing nations have different regulations, such as Aprepitant USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Aprepitant DMF submitted to regulatory agencies in the US is known as a USDMF. Aprepitant USDMF includes data on Aprepitant's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Aprepitant USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Aprepitant suppliers with USDMF on PharmaCompass.

    Aprepitant JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Aprepitant Drug Master File in Japan (Aprepitant JDMF) empowers Aprepitant API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Aprepitant JDMF during the approval evaluation for pharmaceutical products. At the time of Aprepitant JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Aprepitant suppliers with JDMF on PharmaCompass.

    Aprepitant KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Aprepitant Drug Master File in Korea (Aprepitant KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Aprepitant. The MFDS reviews the Aprepitant KDMF as part of the drug registration process and uses the information provided in the Aprepitant KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Aprepitant KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Aprepitant API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Aprepitant suppliers with KDMF on PharmaCompass.

    Aprepitant CEP

    A Aprepitant CEP of the European Pharmacopoeia monograph is often referred to as a Aprepitant Certificate of Suitability (COS). The purpose of a Aprepitant CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Aprepitant EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Aprepitant to their clients by showing that a Aprepitant CEP has been issued for it. The manufacturer submits a Aprepitant CEP (COS) as part of the market authorization procedure, and it takes on the role of a Aprepitant CEP holder for the record. Additionally, the data presented in the Aprepitant CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Aprepitant DMF.

    A Aprepitant CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Aprepitant CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Aprepitant suppliers with CEP (COS) on PharmaCompass.

    Aprepitant WC

    A Aprepitant written confirmation (Aprepitant WC) is an official document issued by a regulatory agency to a Aprepitant manufacturer, verifying that the manufacturing facility of a Aprepitant active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Aprepitant APIs or Aprepitant finished pharmaceutical products to another nation, regulatory agencies frequently require a Aprepitant WC (written confirmation) as part of the regulatory process.

    click here to find a list of Aprepitant suppliers with Written Confirmation (WC) on PharmaCompass.

    Aprepitant NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Aprepitant as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Aprepitant API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Aprepitant as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Aprepitant and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Aprepitant NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Aprepitant suppliers with NDC on PharmaCompass.

    Aprepitant GMP

    Aprepitant Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Aprepitant GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aprepitant GMP manufacturer or Aprepitant GMP API supplier for your needs.

    Aprepitant CoA

    A Aprepitant CoA (Certificate of Analysis) is a formal document that attests to Aprepitant's compliance with Aprepitant specifications and serves as a tool for batch-level quality control.

    Aprepitant CoA mostly includes findings from lab analyses of a specific batch. For each Aprepitant CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Aprepitant may be tested according to a variety of international standards, such as European Pharmacopoeia (Aprepitant EP), Aprepitant JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aprepitant USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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