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1. Anhydrous, Levofloxacin
2. Levaquin
3. Levofloxacin Anhydrous
4. Ofloxacin, (s)-isomer
5. Quixin
1. 100986-85-4
2. Levaquin
3. Quixin
4. (-)-ofloxacin
5. Cravit
6. Iquix
7. Ofloxacin S-(-)-form
8. Tavanic
9. Levofloxacine
10. (s)-ofloxacin
11. L-ofloxacin
12. Levofloxacino
13. Levofloxacinum
14. Oftaquix
15. Floxacin
16. Levofloxacin Anhydrous
17. Dr-3355
18. Nofaxin
19. Volequin
20. Fluoroquinolone
21. Levofloxacin Hydrate
22. Mp-376
23. Levofloxacin (inn)
24. Levofloxacin (levaquin)
25. Rwj-25213
26. Levaquin (tn)
27. Elequine
28. (3s)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7h-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid
29. (s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid
30. Nsc-758709
31. Rix4e89y14
32. 7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3s)-
33. Chebi:63598
34. Quinsair
35. Mfcd00865049
36. (s)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7h-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid
37. Ofloxacin, (s)-
38. Levofloxacin [inn]
39. (s)-(-)-ofloxacin
40. (3s)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic Acid
41. Lfx
42. Levofloxacine [inn-french]
43. Levofloxacinum [inn-latin]
44. Levofloxacino [inn-spanish]
45. Dr3355
46. Hr 355
47. Aeroquin
48. Unibiotic
49. Venaxan
50. Levofloxacin [usan:inn:jan]
51. Loxof
52. Levofloxacin (as Hemihydrate)
53. Rwj 25213-097
54. (2s)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13),6,8,11-tetraene-11-carboxylic Acid
55. (s)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic Acid
56. (s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
57. Smr000466387
58. Cravit (tn)
59. S-(-)-ofloxacin
60. Ccris 4074
61. (s)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2h-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic Acid
62. Levaquin In Dextrose 5% In Plastic Container
63. Unii-rix4e89y14
64. Levofiexacin
65. Ofloxcacin
66. S-ofloxacin
67. Hsdb 8028
68. Cravit Iv
69. Levofloxacin,(s)
70. Anhydrous Ofloxacin
71. Dr-3355: L-isomer Of Ofloxacin
72. (3s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
73. Hr-355
74. Mp 376
75. Spectrum_001719
76. Cpd000466387
77. Spectrum2_001676
78. Spectrum3_000995
79. Spectrum4_001123
80. Spectrum5_001438
81. Schembl15397
82. Bspbio_002689
83. Kbiogr_001605
84. Kbioss_002199
85. (-)-(s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid
86. Fluoro-methyl-(4-methylpiperazin-1-yl)-oxo-[?]carboxylic Acid
87. Mls000759524
88. Mls001165709
89. Mls001423977
90. Levofloxacin [who-dd]
91. Spectrum1504260
92. Spbio_001891
93. Dtxsid0041060
94. Gtpl10911
95. Kbio2_002199
96. Kbio2_004767
97. Kbio2_007335
98. Kbio3_001909
99. Ofloxacin S-(-)-form Hemihydrate
100. Hms1922j07
101. Hms2051g04
102. Hms2090o10
103. Hms2093e18
104. Hms2232g06
105. Pharmakon1600-01504260
106. Zinc538273
107. Ex-a1488
108. Hy-b0330
109. Levofloxacin, >=98.0% (hplc)
110. Bdbm50366826
111. Ccg-39093
112. De-108
113. Mmv687798
114. Nsc755604
115. Nsc758709
116. S1940
117. Ofloxacin S-(-)-form [mi]
118. Akos008901361
119. Akos015895104
120. Ac-7593
121. Db01137
122. Nc00094
123. Nsc 758709
124. Nsc-755604
125. Ncgc00178529-01
126. Ncgc00178529-02
127. Ncgc00178529-03
128. Ncgc00178529-06
129. 7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (s)-
130. As-31796
131. Lvx
132. Levofloxacin, Analytical Reference Material
133. Sbi-0206768.p001
134. L0193
135. C07660
136. D08120
137. Ab00171657-12
138. Ab00171657-13
139. Ab00171657_14
140. Ab00171657_15
141. 986l854
142. Q424193
143. Sr-05000001999
144. Levofloxacin, Antibiotic For Culture Media Use Only
145. Q-201295
146. Sr-05000001999-1
147. Brd-k09471561-001-06-7
148. Tert-butyl?2-(hydroxymethyl)pyrrolidine-1-carboxylate
149. Z1766089137
150. Levofloxacin Solution, 1.0 Mg/ml In Acetonitrile, Certified Reference Material
151. (2s)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic Acid
152. (2s)-7-fluoro-2-methyl-6-(4-methylpiperazin-4-ium-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate
153. (s)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic Acid
Molecular Weight | 361.4 g/mol |
---|---|
Molecular Formula | C18H20FN3O4 |
XLogP3 | -0.4 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 2 |
Exact Mass | 361.14378429 g/mol |
Monoisotopic Mass | 361.14378429 g/mol |
Topological Polar Surface Area | 73.3 Ų |
Heavy Atom Count | 26 |
Formal Charge | 0 |
Complexity | 634 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 1 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
1 of 6 | |
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Drug Name | Levaquin |
PubMed Health | Levofloxacin (Injection) |
Drug Classes | Antibiotic |
Drug Label | LEVAQUIN is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemica... |
Active Ingredient | Levofloxacin |
Dosage Form | Tablet; Injectable; Solution |
Route | Injection; Oral |
Strength | 250mg; 250mg/10ml; 500mg; eq 500mg/20ml (eq 25mg/ml); eq 750mg/30ml (eq 25mg/ml); 750mg |
Market Status | Prescription |
Company | Janssen Pharms |
2 of 6 | |
---|---|
Drug Name | Levofloxacin |
PubMed Health | Levofloxacin |
Drug Classes | Antibiotic |
Drug Label | Levofloxacin is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemi... |
Active Ingredient | sodium chloride; Levofloxacin |
Dosage Form | Solution/drops; Tablet; Injectable; Solution |
Route | injection; Ophthalmic; oral; Injection; Oral |
Strength | 0.5%; 250mg; 250mg/10ml; 500mg; eq 500mg/20ml (eq 25mg/ml); eq 750mg/30ml (eq 25mg/ml); 25mg/ml; 5mg/ml; 750mg |
Market Status | Tentative Approval; Prescription |
Company | Wockhardt; Mylan Pharma; Hospira; Teva; Apotex; Aurobindo Pharma; Torrent Pharms; Lupin; Sandoz; Cipla; Hikma Pharms; Watson Labs; Nexus Pharms; Glenmark Generics; Emcure Pharms; Hi Tech Pharma; Macleods Pharms; Claris Lifesciences; Sagent Pharms; Zydus P |
3 of 6 | |
---|---|
Drug Name | Quixin |
PubMed Health | Levofloxacin |
Drug Classes | Antibiotic |
Drug Label | QUIXIN (levofloxacin ophthalmic solution) 0.5% is a sterile topical ophthalmic solution. Levofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of Gram-positive and Gram-negative ocular pathogens. Levofloxacin is the pure (... |
Active Ingredient | Levofloxacin |
Dosage Form | Solution/drops |
Route | Ophthalmic |
Strength | 0.5% |
Market Status | Prescription |
Company | Santen |
4 of 6 | |
---|---|
Drug Name | Levaquin |
PubMed Health | Levofloxacin (Injection) |
Drug Classes | Antibiotic |
Drug Label | LEVAQUIN is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemica... |
Active Ingredient | Levofloxacin |
Dosage Form | Tablet; Injectable; Solution |
Route | Injection; Oral |
Strength | 250mg; 250mg/10ml; 500mg; eq 500mg/20ml (eq 25mg/ml); eq 750mg/30ml (eq 25mg/ml); 750mg |
Market Status | Prescription |
Company | Janssen Pharms |
5 of 6 | |
---|---|
Drug Name | Levofloxacin |
PubMed Health | Levofloxacin |
Drug Classes | Antibiotic |
Drug Label | Levofloxacin is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemi... |
Active Ingredient | sodium chloride; Levofloxacin |
Dosage Form | Solution/drops; Tablet; Injectable; Solution |
Route | injection; Ophthalmic; oral; Injection; Oral |
Strength | 0.5%; 250mg; 250mg/10ml; 500mg; eq 500mg/20ml (eq 25mg/ml); eq 750mg/30ml (eq 25mg/ml); 25mg/ml; 5mg/ml; 750mg |
Market Status | Tentative Approval; Prescription |
Company | Wockhardt; Mylan Pharma; Hospira; Teva; Apotex; Aurobindo Pharma; Torrent Pharms; Lupin; Sandoz; Cipla; Hikma Pharms; Watson Labs; Nexus Pharms; Glenmark Generics; Emcure Pharms; Hi Tech Pharma; Macleods Pharms; Claris Lifesciences; Sagent Pharms; Zydus P |
6 of 6 | |
---|---|
Drug Name | Quixin |
PubMed Health | Levofloxacin |
Drug Classes | Antibiotic |
Drug Label | QUIXIN (levofloxacin ophthalmic solution) 0.5% is a sterile topical ophthalmic solution. Levofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of Gram-positive and Gram-negative ocular pathogens. Levofloxacin is the pure (... |
Active Ingredient | Levofloxacin |
Dosage Form | Solution/drops |
Route | Ophthalmic |
Strength | 0.5% |
Market Status | Prescription |
Company | Santen |
Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Nucleic Acid Synthesis Inhibitors
National Library of Medicine's Medical Subject Headings online file (MeSH, 2012)
Levofloxacin is used for the treatment of acute bacterial sinusitis caused by susceptible Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis. /Included in US product label/
American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 385
Levofloxacin is used for the treatment of community-acquired pneumonia caused by susceptible S. aureus (oxacillin-susceptible strains), S. pneumoniae (including penicillin-resistant strains (penicillin MIC of 2 ug/mL or greater)), H. influenzae, H. parainfluenzae, Klebsiella pneumoniae, Legionella pneumophila, M. catarrhalis, Chlamydophila pneumoniae (formerly Chlamydia pneumoniae), or Mycoplasma pneumoniae. /Included in US product label/
American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 385
Levofloxacin is used for the treatment of mild to moderate complicated urinary tract infections caused by susceptible E. faecalis, Enterobacter cloacae, E. coli, K. pneumoniae, P. mirabilis, or Ps. aeruginosa and acute pyelonephritis caused by susceptible E. coli, including cases with concurrent bacteremia. /Included in US product label/
American Society of Health-System Pharmacists 2011; Drug Information 2011. Bethesda, MD. 2011, p. 386
For more Therapeutic Uses (Complete) data for Levofloxacin (23 total), please visit the HSDB record page.
/BOXED WARNING/ WARNING: Fluoroquinolones, including Levaquin, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.
US Natl Inst Health; DailyMed. Current Medication Information for LEVAQUIN (levofloxacin) tablet, film coated for oral use; LEVAQUIN (levofloxacin) solution for oral use; LEVAQUIN (levofloxacin) injection, solution, concentrate for intravenous use; LEVAQUIN (levofloxacin) injection, solution for intravenous use (October 2011). Available from, as of March 7, 2012: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a1f01e8e-97e9-11de-b91d-553856d89593
/BOXED WARNING/ WARNING: Fluoroquinolones, including Levaquin may exacerbate muscle weakness in persons with myasthenia gravis. Avoid Levaquin in patients with a known history of myasthenia gravis
US Natl Inst Health; DailyMed. Current Medication Information for LEVAQUIN (levofloxacin) tablet, film coated for oral use; LEVAQUIN (levofloxacin) solution for oral use; LEVAQUIN (levofloxacin) injection, solution, concentrate for intravenous use; LEVAQUIN (levofloxacin) injection, solution for intravenous use (October 2011). Available from, as of March 7, 2012: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a1f01e8e-97e9-11de-b91d-553856d89593
Other serious and sometimes fatal events, some due to hypersensitivity, and some due to uncertain etiology, have been reported rarely in patients receiving therapy with fluoroquinolones, including Levaquin. These events may be severe and generally occur following the administration of multiple doses. Clinical manifestations may include one or more of the following: fever, rash, or severe dermatologic reactions (e.g., toxic epidermal necrolysis, Stevens-Johnson Syndrome); vasculitis; arthralgia; myalgia; serum sickness; allergic pneumonitis; interstitial nephritis; acute renal insufficiency or failure; hepatitis; jaundice; acute hepatic necrosis or failure; anemia, including hemolytic and aplastic; thrombocytopenia, including thrombotic thrombocytopenic purpura; leukopenia; agranulocytosis; pancytopenia; and/or other hematologic abnormalities. The drug should be discontinued immediately at the first appearance of skin rash, jaundice, or any other sign of hypersensitivity and supportive measures instituted.
US Natl Inst Health; DailyMed. Current Medication Information for LEVAQUIN (levofloxacin) tablet, film coated for oral use; LEVAQUIN (levofloxacin) solution for oral use; LEVAQUIN (levofloxacin) injection, solution, concentrate for intravenous use; LEVAQUIN (levofloxacin) injection, solution for intravenous use (October 2011). Available from, as of March 7, 2012: https://dailymed.nlm.nih.gov/dailymed/search.cfm?startswith=levofloxacin
Post-marketing reports of severe hepatotoxicity (including acute hepatitis and fatal events) have been received for patients treated with Levaquin No evidence of serious drug-associated hepatotoxicity was detected in clinical trials of over 7,000 patients. Severe hepatotoxicity generally occurred within 14 days of initiation of therapy and most cases occurred within 6 days. Most cases of severe hepatotoxicity were not associated with hypersensitivity. The majority of fatal hepatotoxicity reports occurred in patients 65 years of age or older and most were not associated with hypersensitivity. Levaquin should be discontinued immediately if the patient develops signs and symptoms of hepatitis.
US Natl Inst Health; DailyMed. Current Medication Information for LEVAQUIN (levofloxacin) tablet, film coated for oral use; LEVAQUIN (levofloxacin) solution for oral use; LEVAQUIN (levofloxacin) injection, solution, concentrate for intravenous use; LEVAQUIN (levofloxacin) injection, solution for intravenous use (October 2011). Available from, as of March 7, 2012: https://dailymed.nlm.nih.gov/dailymed/search.cfm?startswith=levofloxacin
For more Drug Warnings (Complete) data for Levofloxacin (19 total), please visit the HSDB record page.
In oral and intravenous formulations, levofloxacin is indicated in adults for the treatment of various infections caused by susceptible bacteria, including infections of the upper respiratory tract, lower respiratory tract, skin, skin structures, urinary tract, and prostate. The oral formulation is also indicated in both adults and children 6 months of age and older for the post-exposure management of inhalational anthrax caused by _Bacillus anthracis_ and for the treatment and/or prophylaxis of plague caused by _Yersinia pestis_. In its ophthalmic formulation, levofloxacin is indicated for the treatment of bacterial conjunctivitis caused by susceptible organisms. An inhalational solution available in Canada is indicated for the management of cystic fibrosis patients aged 18 years or older with chronic pulmonary _Pseudomonas aeruginosa_ infections.
FDA Label
Quinsair is indicated for the management of chronic pulmonary infections due to Pseudomonas aeruginosa in adult patients with cystic fibrosis.
Consideration should be given to official guidance on the appropriate use of antibacterial agents.