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    Chemistry

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    Also known as: 7732-18-5, Distilled water, Dihydrogen oxide, Sterile water, Purified water, Water vapor
    Molecular Formula
    H2O
    Molecular Weight
    18.015  g/mol
    InChI Key
    XLYOFNOQVPJJNP-UHFFFAOYSA-N
    FDA UNII
    059QF0KO0R
    Water
    A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
    1 2D Structure

    Water

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    oxidane
    2.1.2 InChI
    InChI=1S/H2O/h1H2
    2.1.3 InChI Key
    XLYOFNOQVPJJNP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    O
    2.2 Other Identifiers
    2.2.1 UNII
    059QF0KO0R
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Hydrogen Oxide

    2.3.2 Depositor-Supplied Synonyms

    1. 7732-18-5

    2. Distilled Water

    3. Dihydrogen Oxide

    4. Sterile Water

    5. Purified Water

    6. Water Vapor

    7. Water, Deionized

    8. Oxidane

    9. Water, Purified

    10. Oxygen Atom

    11. Dihydrogen Monoxide

    12. Aqua

    13. Steam

    14. Dhmo

    15. Deionized Water

    16. Water For Injection

    17. Sterile Water For Irrigation

    18. Sterile Purified Water

    19. Water For Hemodialysis

    20. Ccris 6115

    21. 1,3-epoxy-

    22. Water, Purified Sterile

    23. Water, Sterile Purified

    24. Water Purified

    25. Sterile Water For Injection

    26. Sterile Water For Inhalation

    27. Ultrex Ii Ultrapure

    28. Water For Inhalation, Sterile

    29. Water, Hplc

    30. Water, Hplc Grade

    31. H2o

    32. Water, Depc-treated

    33. Deuterium Cdepleted Water

    34. Mfcd00011332

    35. Nsc-147337

    36. 059qf0ko0r

    37. Chebi:15377

    38. Water, Mineral

    39. Water, For Hplc

    40. Water, D.i.u.f.

    41. Nsc 147337; R 718

    42. R-718

    43. Water, Sterile

    44. Water, Distilled

    45. Detergent, Neutral Reagent

    46. Hoh

    47. Deionized Ultra-filtered Water

    48. 20% Acetonitrile/80% Water

    49. Hydrochloric Acid Solution, 6n

    50. Agua

    51. Water, Sterile-filtered, Bioreagent, Suitable For Cell Culture

    52. Aqua Purificata

    53. Pur-wash

    54. Ipa (isopropyl Alcohol), 70% V/v

    55. Hydrochloric Acid, 25% (v/v) (1+3)

    56. Buffer Solution, Ph 10.00, Color-coded Blue

    57. Sterile Water In Plastic Container

    58. Einecs 231-791-2

    59. Nsc 147337

    60. Acqua

    61. Dihydridooxygen

    62. (tris)-1, 10-phenanthroline Iron (ii) Sulfate Solution

    63. Unii-059qf0ko0r

    64. Water For Injection, Sterile

    65. Adelheidsquelle

    66. Tritiotope

    67. Wiesbaden

    68. Wasser

    69. Water For Irrigation, Sterile

    70. Hydroxy Radical

    71. Water,deionized

    72. Water,distilled

    73. Water,sanitized

    74. Adelheid Aqua

    75. Aqua Adelheid

    76. Aqua Wiesbaden

    77. Water,purified

    78. Water,sterile

    79. Wiesbaden Aqua

    80. Aqua Wildbad

    81. Wildbad Aqua

    82. Water-

    83. Di Water

    84. Hsdb 8183

    85. Hydrogen Hydroxide

    86. Bacteriostatic Water For Injection

    87. Sterile Water For Injection In Plastic Container

    88. Water For Injection, Bacteriostatic

    89. Aqua Pro Injectione

    90. Eau

    91. Pure Water Density Standard, Ukas Iso/iec17025 And Iso Guide 34 Certified, Density: 0.9982 G/ml At 20 C, Density: 0.9970 G/ml At 25 C

    92. Water,bacteriostatic

    93. Water For Injections

    94. Water, Acs Reagent

    95. Water, Hplc Plus

    96. Water, Lcms Grade

    97. Aquafina

    98. Water, Pcr Reagent

    99. Bacteriostatic Water For Injection In Plastic Container

    100. Sterile Water (tn)

    101. Water, Lc/ms

    102. Water, Endotoxin-free

    103. Water With Tfa, Tfa

    104. An Unknown Oxygen Source

    105. Water [vandf]

    106. Water, Optima Uhplcms

    107. Water, Purified (usp)

    108. H-oh

    109. Water [inci]

    110. Ddwater (endotoxin-free)

    111. Purified Water (jp17)

    112. Water (jp17/usp)

    113. Water, For Toc Analysis

    114. Aqua [inci]

    115. Water [jan]

    116. Water [who-dd]

    117. Water [mi]

    118. Distilled Water, For Hplc

    119. Water, Deionized (<2us)

    120. Water, Rnase, Dnase-free

    121. 0.05% Tfa In Water

    122. Pure Water Density Standard

    123. Sterile Water For Injections

    124. Water For Irrigation,sterile

    125. Water, Hplc Gradient Grade

    126. Water, Deionized (<10us)

    127. Water, Demineralized, P.a.

    128. Water,bacteriostatic Injection

    129. Water For Injection (jp17)

    130. Water, Distilled, Conductivity Or Of Similar Purity

    131. Water, For Ion Chromatography

    132. Water,reagent(deionizedwater)

    133. B1217 [langual]

    134. Hydrogen Oxide (h2o)

    135. Density Standard 998 Kg/m3

    136. Hydrofluoric Acid, 48-50%

    137. Aqua Sterilisata Pro Injectione

    138. Water, Ultrapure, Hplc Grade

    139. Water, Bioperformance Certified

    140. Purified Water [mart.]

    141. Chembl1098659

    142. Dtxsid6026296

    143. Chebi:25805

    144. Water, Molecular Biology Reagent

    145. Xlyofnoqvpjjnp-uhfffaoysa-

    146. Diethylpyrocarbonate-treated Water

    147. Dtxsid00170378

    148. Water, Reagent (deionized Water)

    149. [oh2]

    150. Water, Tested According To Ph.eur.

    151. Nsc147337

    152. Purified Water In Containers (jp17)

    153. Akos015950726

    154. E-toxate(tm) Water, Endotoxin, Free

    155. Water With 0.1% Trifluoroacetic Acid

    156. Db09145

    157. Water With 0.05% Trifluoroacetic Acid

    158. Water, For Uhplc, For Mass Spectrometry

    159. Q283

    160. Water For Injection In Containers (jp17)

    161. Water, Ultrapure, Spectrophotometric Grade

    162. Ft-0666297

    163. Ft-0696358

    164. Ft-0696590

    165. Ft-0696628

    166. Ft-0696641

    167. Ft-0696971

    168. Ft-0697004

    169. Ft-0697144

    170. Ft-0697158

    171. Ft-0697170

    172. Ft-0697209

    173. Ft-0697243

    174. Ft-0697253

    175. Ft-0697259

    176. Ft-0697294

    177. Ft-0697297

    178. Ft-0697301

    179. Ft-0697341

    180. Ft-0697349

    181. Ft-0697357

    182. Ft-0697405

    183. Ft-0697446

    184. Ft-0697449

    185. Ft-0697507

    186. Ft-0697572

    187. Ft-0697623

    188. Ft-0697627

    189. Ft-0697628

    190. Ft-0697674

    191. Ft-0697714

    192. Ft-0697757

    193. Ft-0697788

    194. Ft-0697792

    195. Ft-0697796

    196. Ft-0697843

    197. Ft-0697856

    198. Ft-0697866

    199. Ft-0697871

    200. Ft-0697889

    201. Ft-0697898

    202. Ft-0697905

    203. Ft-0697910

    204. Ft-0697922

    205. Ft-0698010

    206. Ft-0698017

    207. Ft-0698043

    208. Ft-0698101

    209. Ft-0698115

    210. Ft-0698166

    211. Ft-0698169

    212. Ft-0698223

    213. Ft-0698239

    214. Ft-0698270

    215. Ft-0698271

    216. Ft-0698321

    217. Ft-0698348

    218. Ft-0698364

    219. Ft-0698424

    220. Ft-0698457

    221. Ft-0698465

    222. Ft-0698477

    223. Ft-0698494

    224. Ft-0698589

    225. Ft-0698592

    226. Ft-0698708

    227. Ft-0698717

    228. Ft-0698718

    229. Ft-0698751

    230. Ft-0698783

    231. Ft-0698819

    232. Ft-0698821

    233. Ft-0698831

    234. Ft-0698832

    235. Ft-0698834

    236. Ft-0698835

    237. Ft-0698842

    238. Ft-0698843

    239. Ft-0698847

    240. Ft-0698849

    241. Ft-0698856

    242. Ft-0698897

    243. Ft-0698914

    244. Ft-0698990

    245. Ft-0698992

    246. Ft-0698993

    247. Ft-0698996

    248. Ft-0698999

    249. Ft-0699000

    250. Ft-0699001

    251. Ft-0699002

    252. Ft-0699003

    253. Ft-0699004

    254. Ft-0699005

    255. Ft-0699007

    256. Ft-0699017

    257. Ft-0699037

    258. Ft-0699049

    259. Ft-0699053

    260. Ft-0699078

    261. Ft-0699128

    262. Ft-0699173

    263. Ft-0699177

    264. Ft-0699181

    265. Ft-0699195

    266. Ft-0699197

    267. Ft-0699222

    268. Ft-0699237

    269. Ft-0699244

    270. Ft-0699257

    271. Ft-0699263

    272. Ft-0699270

    273. Ft-0699281

    274. Ft-0699301

    275. Ft-0699381

    276. Ft-0699391

    277. Ft-0699491

    278. Ft-0699565

    279. Ft-0699582

    280. Ft-0699656

    281. Ft-0699660

    282. Ft-0699667

    283. Ft-0699668

    284. Ft-0699680

    285. Ft-0699707

    286. Ft-0699726

    287. Ft-0699727

    288. Ft-0699728

    289. Ft-0699749

    290. Ft-0699751

    291. Ft-0699763

    292. Ft-0699780

    293. Ft-0699822

    294. Ft-0699826

    295. Sterile Purified Water In Containers (jp17)

    296. Water, Acs Reagent, For Ultratrace Analysis

    297. Water With 0.1% Trifluoroacetic Acid (v/v)

    298. Water, Packaged For Use In Deposition Systems

    299. C00001

    300. D00001

    301. Water With 0.05% Trifluoroacetic Acid (v/v)

    302. Water, Deuterium-depleted, 99.99995 Atom %

    303. Q274959

    304. Q427071

    305. Water Solution, 0.005n In Sulfuric Acid, For Hplc

    306. Water Solution, Contains 0.05 % (v/v) Acetic Acid

    307. Water Solution, Contains 0.10 % (v/v) Acetic Acid

    308. Water, Deuterium-depleted, <=1 Ppm (deuterium Oxide)

    309. Water, For Hpce, For Luminescence, For Uv-spectroscopy

    310. Density Standard 998 Kg/m3, H&d Fitzgerald Ltd. Quality

    311. Water Solution, Contains 0.1 % (v/v) Ammonium Hydroxide

    312. Water Solution, Contains 10 Mm Ammonium Acetate, For Hplc

    313. Water Solution, Contains 0.05 % (v/v) Trifluoroacetic Acid

    314. Water Solution, Contains 0.06 % (v/v) Trifluoroacetic Acid

    315. Water Solution, For Hplc, Contains 0.1 % (v/v) Formic Acid

    316. Water, For Molecular Biology, Depc-treated And Sterile Filtered

    317. Water Solution, Hplc Grade, Contains 0.035 % (v/v) Acetic Acid

    318. Water Solution, Contains 0.1 % (v/v) Trifluoroacetic Acid, For Hplc

    319. Water, 99.999%, Contained In 50 Ml Swagelok? Cylinder For Cvd/ald

    320. Water, Deionized 18 Megaohm Astm Type I, Suitable For Trace Metal Analysis

    321. Water, For Cell Biology, Free Of Endotoxins, Ultrafiltered And Autoclaved

    322. Water Solution, Contains 0.05 % (w/v) Ammonium Formate, 0.1 % (v/v) Formic Acid

    323. Water Solution, Contains 0.1 % (v/v) Formic Acid, For Uhplc, For Mass Spectrometry

    324. Water Solution, Contains 0.10 % (v/v) Formic Acid, 50.0 % (v/v) Acetonitrile

    325. Water Solution, Contains 10.0 % (v/v) Methanol, 0.10 % (v/v) Trifluoroacetic Acid

    326. Water Solution, Contains 20 % (v/v) Acetonitrile, 0.1 % (v/v) Formic Acid

    327. Water, For Embryo Transfer, Sterile-filtered, Bioxtra, Suitable For Mouse Embryo

    328. 8o

    329. Oh2

    2.4 Create Date
    2004-09-16
    3 Chemical and Physical Properties
    Molecular Weight 18.015 g/mol
    Molecular Formula H2O
    XLogP3-0.5
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass18.010564683 g/mol
    Monoisotopic Mass18.010564683 g/mol
    Topological Polar Surface Area1 Ų
    Heavy Atom Count1
    Formal Charge0
    Complexity0
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 8  
    Drug NameBacteriostatic water for injection in plastic container
    Drug LabelSterile Water for Injection USP is a clear, colorless, odorless liquid. It is sterile, hypotonic, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents. Sterile Water for Injection USP is a diluent suitable for intravascular injection...
    Active IngredientSterile water for injection
    Dosage FormLiquid
    RouteN/a
    Strength100%
    Market StatusPrescription
    CompanyHospira

    2 of 8  
    Drug NameSterile water
    Active IngredientSterile water for irrigation; Sterile water
    Dosage FormInjectable; Liquid
    Routeinjection; Irrigation
    Strength100%; 10ml
    Market StatusPrescription
    CompanyBaxter Hlthcare; Taro Pharms Ireland

    3 of 8  
    Drug NameSterile water for injection in plastic container
    Active IngredientSterile water for injection
    Dosage FormLiquid
    RouteN/a
    Strength100%
    Market StatusPrescription
    CompanyHospira; Baxter Hlthcare; Fresenius Kabi Usa; B Braun; Taro Pharms Ireland

    4 of 8  
    Drug NameSterile water in plastic container
    Active IngredientSterile water for irrigation
    Dosage FormLiquid
    RouteIrrigation
    Strength100%
    Market StatusPrescription
    CompanyHospira; Baxter Hlthcare; B Braun

    5 of 8  
    Drug NameBacteriostatic water for injection in plastic container
    Drug LabelSterile Water for Injection USP is a clear, colorless, odorless liquid. It is sterile, hypotonic, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents. Sterile Water for Injection USP is a diluent suitable for intravascular injection...
    Active IngredientSterile water for injection
    Dosage FormLiquid
    RouteN/a
    Strength100%
    Market StatusPrescription
    CompanyHospira

    6 of 8  
    Drug NameSterile water
    Active IngredientSterile water for irrigation; Sterile water
    Dosage FormInjectable; Liquid
    Routeinjection; Irrigation
    Strength100%; 10ml
    Market StatusPrescription
    CompanyBaxter Hlthcare; Taro Pharms Ireland

    7 of 8  
    Drug NameSterile water for injection in plastic container
    Active IngredientSterile water for injection
    Dosage FormLiquid
    RouteN/a
    Strength100%
    Market StatusPrescription
    CompanyHospira; Baxter Hlthcare; Fresenius Kabi Usa; B Braun; Taro Pharms Ireland

    8 of 8  
    Drug NameSterile water in plastic container
    Active IngredientSterile water for irrigation
    Dosage FormLiquid
    RouteIrrigation
    Strength100%
    Market StatusPrescription
    CompanyHospira; Baxter Hlthcare; B Braun

    4.2 Drug Indication

    For diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.

    FDA Label

    5 Pharmacology and Biochemistry
    5.1 Absorption, Distribution and Excretion

    Tritium radioactivity in mouse fetus taken from the pregnant female mouse which had been given tritium containing drinking water was measured to estimate the absorbed radiation dose from the incorporated tritium. BC3F1 female mice mated with ICR male were given drinking water containing various concentrations of tritium for whole pregnant period, from the morning when the vaginal plug was observed to the day just before term. At various times of the pregnant period, blood and fetuses were taken from the female mice to measure the tritium concentration using a Packard model of sample oxidizer. The absorbed radiation dose of the fetus from the incorporated tritium was estimated on the basis of the tritium concentration measured. The tritium concentration of the embryos increased gradually from the first pregnant day to reach the plateau level at the 7 to 9th day. The estimated radiation dose increased almost linearly depending on the tritium concentration in the drinking water. /Tritium containing drinking water/

    Yamada T et al; J Radiat Res (Tokyo) 32 (1): 91 (1991)

    API Reference Price

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    01-Jan-2022
    31-May-2025
    KGS
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    ABOUT THIS PAGE

    Looking for 7732-18-5 / Water API manufacturers, exporters & distributors?

    Water manufacturers, exporters & distributors 1

    23

    PharmaCompass offers a list of Water API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Water manufacturer or Water supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Water manufacturer or Water supplier.

    PharmaCompass also assists you with knowing the Water API Price utilized in the formulation of products. Water API Price is not always fixed or binding as the Water Price is obtained through a variety of data sources. The Water Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Water

    Synonyms

    7732-18-5, Distilled water, Dihydrogen oxide, Sterile water, Purified water, Water vapor

    Cas Number

    7732-18-5

    Unique Ingredient Identifier (UNII)

    059QF0KO0R

    About Water

    A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)

    Water Manufacturers

    A Water manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Water, including repackagers and relabelers. The FDA regulates Water manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Water API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Water manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Water Suppliers

    A Water supplier is an individual or a company that provides Water active pharmaceutical ingredient (API) or Water finished formulations upon request. The Water suppliers may include Water API manufacturers, exporters, distributors and traders.

    click here to find a list of Water suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Water USDMF

    A Water DMF (Drug Master File) is a document detailing the whole manufacturing process of Water active pharmaceutical ingredient (API) in detail. Different forms of Water DMFs exist exist since differing nations have different regulations, such as Water USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Water DMF submitted to regulatory agencies in the US is known as a USDMF. Water USDMF includes data on Water's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Water USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Water suppliers with USDMF on PharmaCompass.

    Water CEP

    A Water CEP of the European Pharmacopoeia monograph is often referred to as a Water Certificate of Suitability (COS). The purpose of a Water CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Water EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Water to their clients by showing that a Water CEP has been issued for it. The manufacturer submits a Water CEP (COS) as part of the market authorization procedure, and it takes on the role of a Water CEP holder for the record. Additionally, the data presented in the Water CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Water DMF.

    A Water CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Water CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Water suppliers with CEP (COS) on PharmaCompass.

    Water NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Water as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Water API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Water as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Water and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Water NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Water suppliers with NDC on PharmaCompass.

    Water GMP

    Water Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Water GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Water GMP manufacturer or Water GMP API supplier for your needs.

    Water CoA

    A Water CoA (Certificate of Analysis) is a formal document that attests to Water's compliance with Water specifications and serves as a tool for batch-level quality control.

    Water CoA mostly includes findings from lab analyses of a specific batch. For each Water CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Water may be tested according to a variety of international standards, such as European Pharmacopoeia (Water EP), Water JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Water USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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