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    Synopsis

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    Chemistry

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    Also known as: 137862-53-4, Diovan, Tareg, Cgp 48933, Provas, Exforge
    Molecular Formula
    C24H29N5O3
    Molecular Weight
    435.5  g/mol
    InChI Key
    ACWBQPMHZXGDFX-QFIPXVFZSA-N
    FDA UNII
    80M03YXJ7I
    Valsartan
    A tetrazole derivative and ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to treat HYPERTENSION.
    Valsartan is an Angiotensin 2 Receptor Blocker. The mechanism of action of valsartan is as an Angiotensin 2 Receptor Antagonist.
    1 2D Structure

    Valsartan

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
    2.1.2 InChI
    InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
    2.1.3 InChI Key
    ACWBQPMHZXGDFX-QFIPXVFZSA-N
    2.1.4 Canonical SMILES
    CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
    2.1.5 Isomeric SMILES
    CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    80M03YXJ7I
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 48933, Cgp

    2. Cgp 48933

    3. Diovan

    4. Kalpress

    5. Miten

    6. N-valeryl-n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)valine

    7. Nisis

    8. Provas

    9. Tareg

    10. Vals

    2.3.2 Depositor-Supplied Synonyms

    1. 137862-53-4

    2. Diovan

    3. Tareg

    4. Cgp 48933

    5. Provas

    6. Exforge

    7. Cgp-48933

    8. (s)-2-(n-((2'-(1h-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic Acid

    9. 137863-60-6

    10. Prexxartan

    11. Mfcd00865840

    12. N-(p-(o-1h-tetrazol-5-ylphenyl)benzyl)-n-valeryl-l-valine

    13. (2s)-3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic Acid

    14. Nsc-758927

    15. Chembl1069

    16. L-valine, N-(1-oxopentyl)-n-[[2'-(2h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-

    17. 80m03yxj7i

    18. Chebi:9927

    19. (s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic Acid

    20. L-valine, N-(1-oxopentyl)-n-((2'-(1h-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-

    21. Kalpress

    22. Miten

    23. Nisis

    24. Vals

    25. (s)-n-valeryl-n-{[2'-(1h-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine

    26. N-(1-oxopentyl)-n-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-l-valine

    27. Valzaar

    28. Valtan

    29. [3h]valsartan

    30. (2~{s})-3-methyl-2-[pentanoyl-[[4-[2-(2~{h}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic Acid

    31. Smr000466318

    32. Diovan (tn)

    33. Unii-80m03yxj7i

    34. Valpression

    35. Valsartana

    36. Varexan

    37. Hsdb 7519

    38. Valsartan [usan:usp:inn:ban]

    39. Valsartan,(s)

    40. Valsartan- Bio-x

    41. (2s)-3-methyl-2-(pentanoyl-((4-(2-(2h-tetrazol-5-yl)phenyl)phenyl)methyl)amino)butanoic Acid

    42. (2s)-3-methyl-2-[pentanoyl-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic Acid

    43. Valsartan (diovan)

    44. Spectrum_001796

    45. Valsartan [inn]

    46. Valsartan [jan]

    47. Valsartan [mi]

    48. Valsartan [hsdb]

    49. Valsartan [usan]

    50. Spectrum2_001120

    51. Spectrum3_001831

    52. Spectrum4_000749

    53. Spectrum5_001582

    54. Valsartan [vandf]

    55. Prexxartan (oral Solution)

    56. Valsartan [mart.]

    57. Ec 604-045-2

    58. Schembl2542

    59. Valsartan [usp-rs]

    60. Valsartan [who-dd]

    61. Bspbio_003501

    62. Gtpl593

    63. Kbiogr_001078

    64. Kbioss_002289

    65. Valsartan [ema Epar]

    66. Mls000759423

    67. Mls001424088

    68. Bidd:gt0345

    69. Spectrum1505209

    70. Spbio_001260

    71. Valsartan (jp17/usp/inn)

    72. Gtpl3937

    73. Valsartan [ep Impurity]

    74. Valsartan [orange Book]

    75. Dtxsid6023735

    76. Valsartan [ep Monograph]

    77. Valsartan, >=98% (hplc)

    78. Dafiro Component Valsartan

    79. Kbio2_002287

    80. Kbio2_004855

    81. Kbio2_007423

    82. Kbio3_003006

    83. Ezr-104

    84. Val-489

    85. Valsartan [usp Monograph]

    86. Copalia Component Valsartan

    87. Exforge Component Valsartan

    88. Imprida Component Valsartan

    89. Hms1922l21

    90. Hms2051l12

    91. Hms2093k22

    92. Hms2232f05

    93. Hms3651e04

    94. Hms3715p12

    95. Pharmakon1600-01505209

    96. Entresto Component Valsartan

    97. Valturna Component Valsartan

    98. (2r)-3-methyl-2-[pentanoyl[[2'-(1h-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoic Acid (valsartan (r)-enantiomer)

    99. Act02671

    100. Bcp05184

    101. Zinc3875259

    102. Bdbm50049186

    103. Nsc758927

    104. S1894

    105. Dafiro-hct Component Valsartan

    106. Diovan Hct Component Valsartan

    107. Valsartan Component Of Copalia

    108.