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    Chemistry

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    Also known as: 111470-99-6, Amlodipine besilate, Amlodipine benzenesulfonate, Antacal, Monopina, Istin
    Molecular Formula
    C26H31ClN2O8S
    Molecular Weight
    567.1  g/mol
    InChI Key
    ZPBWCRDSRKPIDG-UHFFFAOYSA-N
    FDA UNII
    864V2Q084H
    Amlodipine Besylate
    A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
    1 2D Structure

    Amlodipine Besylate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
    2.1.2 InChI
    InChI=1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)
    2.1.3 InChI Key
    ZPBWCRDSRKPIDG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    864V2Q084H
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Amlodipine

    2. Amlodipine Maleate

    3. Amlodipine Maleate (1:1)

    4. Amlodipine, (+-)-isomer

    5. Amlodipine, (+-)-isomer, Maleate (1:1)

    6. Amlodipine, (r)-isomer

    7. Amlodipine, (s)-isomer, Maleate (1:1)

    8. Amlodis

    9. Amlor

    10. Astudal

    11. Istin

    12. Norvasc

    2.3.2 Depositor-Supplied Synonyms

    1. 111470-99-6

    2. Amlodipine Besilate

    3. Amlodipine Benzenesulfonate

    4. Antacal

    5. Monopina

    6. Istin

    7. Amlodipine (besylate)

    8. Amdepin

    9. Amdipin

    10. Amlodin

    11. Pelmec

    12. 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate

    13. Lodipressin

    14. Amlor

    15. Amlodipine (as Besilate)

    16. Nsc-758922

    17. (s)-amlodipine;levoamlodipine

    18. Amlodipine Besylate (norvasc)

    19. Chebi:2669

    20. Cardiorex

    21. Uk-48,340-26

    22. 111470-99-6 (besylate)

    23. 864v2q084h

    24. 3,5-pyridinedicarboxylic Acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl Ester, (+-)-, Monobenzenesulfonate

    25. Ncgc00095835-01

    26. Amlogard

    27. Amlopin

    28. Amlosyn

    29. Astudar

    30. Cordarene

    31. Myodura

    32. Norlopin

    33. Norvask

    34. Tensivask

    35. Amcard

    36. Norvas

    37. Terloc

    38. Norvasc (tn)

    39. Uk-48340-26

    40. (s)-amlodipine Besylate;levoamlodipine Besylate

    41. Dsstox_cid_23909

    42. Dsstox_rid_80087

    43. Dsstox_gsid_43909

    44. Benzenesulfonic Acid;3-o-ethyl 5-o-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

    45. Stamlo

    46. Amlodipine Besylate [usan]

    47. Cas-111470-99-6

    48. C20h25cln2o5.c6h6o3s

    49. Ncgc00165957-04

    50. Amlodipine 100 Microg/ml In Acetonitrile

    51. Unii-864v2q084h

    52. Amlodipine Besylate [usan:usp]

    53. Uk 48340-26

    54. 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate

    55. Mfcd00887594

    56. Norliqva

    57. Spectrum_000573

    58. Amlodipine Benzenesulphonate

    59. Amlodipine Besylate (usp)

    60. Amlodipine Besylate- Bio-x

    61. Amlodipine Besilate (jp17)

    62. Schembl41282

    63. Kbioss_001053

    64. 3-ethyl 5-methyl (+-)-2-((2-aminoethoxy)methyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate, Monobenzenesulfonate

    65. Mls001361394

    66. Spectrum1505202

    67. Chembl1200402

    68. Chembl3193637

    69. Chembl3207778

    70. Dtxsid2043909

    71. Hy-b0317b

    72. Kbio2_001053

    73. Kbio2_003621

    74. Kbio2_006189

    75. Amlodipine Besilate [jan]

    76. Amlodipine Besylate [hsdb]

    77. Hms2094e13

    78. Hms2232d22

    79. Hms2235b19

    80. Hms3269b19

    81. Hms3372o18

    82. Hms3373f15

    83. Hms3413h11

    84. Hms3677h11

    85. Hms3884m10

    86.&nb