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    Chemistry

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    Also known as:
    Molecular Formula
    C8H11N5O3
    Molecular Weight
    225.20  g/mol
    InChI Key
    MKUXAQIIEYXACX-UHFFFAOYSA-N
    Acyclovir
    1 2D Structure

    Acyclovir

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one
    2.1.2 InChI
    InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
    2.1.3 InChI Key
    MKUXAQIIEYXACX-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1=NC2=C(N1COCCO)NC(=NC2=O)N
    2.1.5 Isomeric SMILES
    C1=NC2=C(N1COCCO)NC(=NC2=O)N
    2.2 Create Date
    2005-03-25
    3 Chemical and Physical Properties
    Molecular Weight 225.20 g/mol
    Molecular Formula C8H11N5O3
    XLogP3-1.6
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count4
    Exact Mass225.08618923 g/mol
    Monoisotopic Mass225.08618923 g/mol
    Topological Polar Surface Area115 A^2
    Heavy Atom Count16
    Formal Charge0
    Complexity308
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 8  
    Drug NameAcyclovir
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Capsule; Suspension
    RouteTopical; Oral
    Strength5%; 200mg/5ml; 200mg; 800mg; 400mg
    Market StatusPrescription
    CompanyAmneal Pharms; Mylan Pharms; Ranbaxy; Hetero Labs Ltd V; Hi Tech Pharma; Actavis Mid Atlantic; Teva; Cadila Pharms; Apotex; Zydus Pharms Usa; Carlsbad; Mylan; Stason; Dava Pharms

    2 of 8  
    Drug NameAcyclovir sodium
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    3 of 8  
    Drug NameSitavig
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelSITAVIG (acyclovir) buccal tablet is applied topically to the gum and releases acyclovir as the buccal tablet gradually dissolves [see ClinicalPharmacology (12.3)]. Acyclovir is a synthetic purine nucleoside analogue active against herpes viruses. Th...
    Active IngredientAcyclovir
    Dosage FormTablet
    RouteBuccal
    Strength50mg
    Market StatusPrescription
    CompanyInnocutis Holdings

    4 of 8  
    Drug NameZovirax
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Cream; Capsule; Suspension
    RouteOral; Topical
    Strength200mg/5ml; 200mg; 800mg; 400mg; 5%
    Market StatusPrescription
    CompanyDelcor Asset; Valeant Bermuda

    5 of 8  
    Drug NameAcyclovir
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Capsule; Suspension
    RouteTopical; Oral
    Strength5%; 200mg/5ml; 200mg; 800mg; 400mg
    Market StatusPrescription
    CompanyAmneal Pharms; Mylan Pharms; Ranbaxy; Hetero Labs Ltd V; Hi Tech Pharma; Actavis Mid Atlantic; Teva; Cadila Pharms; Apotex; Zydus Pharms Usa; Carlsbad; Mylan; Stason; Dava Pharms

    6 of 8  
    Drug NameAcyclovir sodium
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelAcyclovir is a synthetic nucleoside analog active against herpes viruses. Acyclovir for Injection USP is a sterile lyophilized powder for intravenous administration only. Each 500 mg vial contains 500 mg of acyclovir and 49 mg of sodium, and each 100...
    Active IngredientAcyclovir sodium
    Dosage FormInjectable
    RouteInjection
    Strengtheq 50mg base/ml; eq 500mg base/vial; eq 1gm base/vial
    Market StatusPrescription
    CompanyBedford; Fresenius Kabi Usa; Aurobindo Pharma

    7 of 8  
    Drug NameSitavig
    PubMed HealthAcyclovir
    Drug ClassesAntiviral
    Drug LabelSITAVIG (acyclovir) buccal tablet is applied topically to the gum and releases acyclovir as the buccal tablet gradually dissolves [see ClinicalPharmacology (12.3)]. Acyclovir is a synthetic purine nucleoside analogue active against herpes viruses. Th...
    Active IngredientAcyclovir
    Dosage FormTablet
    RouteBuccal
    Strength50mg
    Market StatusPrescription
    CompanyInnocutis Holdings

    8 of 8  
    Drug NameZovirax
    Drug LabelZOVIRAX is the brand name for acyclovir, a synthetic nucleoside analogue active against herpesviruses. ZOVIRAX Cream 5% is a formulation for topical administration. Each gram of ZOVIRAXCream 5% contains 50mg of acyclovir and the following inactiv...
    Active IngredientAcyclovir
    Dosage FormOintment; Tablet; Cream; Capsule; Suspension
    RouteOral; Topical
    Strength200mg/5ml; 200mg; 800mg; 400mg; 5%
    Market StatusPrescription
    CompanyDelcor Asset; Valeant Bermuda

    API Reference Price

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    01-Jan-2022
    30-May-2025
    KGS
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    DOSAGE - CAPSULE;ORAL - 200MG **Federal Regis...DOSAGE - CAPSULE;ORAL - 200MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 18828

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    DOSAGE - SUSPENSION;ORAL - 200MG/5ML

    USFDA APPLICATION NUMBER - 19909

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    DOSAGE - TABLET;ORAL - 400MG **Federal Regist...DOSAGE - TABLET;ORAL - 400MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20089

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    DOSAGE - TABLET;ORAL - 800MG **Federal Regist...DOSAGE - TABLET;ORAL - 800MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20089

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    DOSAGE - CREAM;TOPICAL - 5%;1%

    USFDA APPLICATION NUMBER - 22436

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    Looking for / Acyclovir API manufacturers, exporters & distributors?

    Acyclovir manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Acyclovir API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Acyclovir manufacturer or Acyclovir supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Acyclovir manufacturer or Acyclovir supplier.

    PharmaCompass also assists you with knowing the Acyclovir API Price utilized in the formulation of products. Acyclovir API Price is not always fixed or binding as the Acyclovir Price is obtained through a variety of data sources. The Acyclovir Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Acyclovir

    Aciclovir Manufacturers

    A Aciclovir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aciclovir, including repackagers and relabelers. The FDA regulates Aciclovir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aciclovir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Aciclovir manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Aciclovir Suppliers

    A Aciclovir supplier is an individual or a company that provides Aciclovir active pharmaceutical ingredient (API) or Aciclovir finished formulations upon request. The Aciclovir suppliers may include Aciclovir API manufacturers, exporters, distributors and traders.

    click here to find a list of Aciclovir suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Aciclovir USDMF

    A Aciclovir DMF (Drug Master File) is a document detailing the whole manufacturing process of Aciclovir active pharmaceutical ingredient (API) in detail. Different forms of Aciclovir DMFs exist exist since differing nations have different regulations, such as Aciclovir USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Aciclovir DMF submitted to regulatory agencies in the US is known as a USDMF. Aciclovir USDMF includes data on Aciclovir's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Aciclovir USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Aciclovir suppliers with USDMF on PharmaCompass.

    Aciclovir JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Aciclovir Drug Master File in Japan (Aciclovir JDMF) empowers Aciclovir API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Aciclovir JDMF during the approval evaluation for pharmaceutical products. At the time of Aciclovir JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Aciclovir suppliers with JDMF on PharmaCompass.

    Aciclovir KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Aciclovir Drug Master File in Korea (Aciclovir KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Aciclovir. The MFDS reviews the Aciclovir KDMF as part of the drug registration process and uses the information provided in the Aciclovir KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Aciclovir KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Aciclovir API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Aciclovir suppliers with KDMF on PharmaCompass.

    Aciclovir CEP

    A Aciclovir CEP of the European Pharmacopoeia monograph is often referred to as a Aciclovir Certificate of Suitability (COS). The purpose of a Aciclovir CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Aciclovir EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Aciclovir to their clients by showing that a Aciclovir CEP has been issued for it. The manufacturer submits a Aciclovir CEP (COS) as part of the market authorization procedure, and it takes on the role of a Aciclovir CEP holder for the record. Additionally, the data presented in the Aciclovir CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Aciclovir DMF.

    A Aciclovir CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Aciclovir CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Aciclovir suppliers with CEP (COS) on PharmaCompass.

    Aciclovir WC

    A Aciclovir written confirmation (Aciclovir WC) is an official document issued by a regulatory agency to a Aciclovir manufacturer, verifying that the manufacturing facility of a Aciclovir active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Aciclovir APIs or Aciclovir finished pharmaceutical products to another nation, regulatory agencies frequently require a Aciclovir WC (written confirmation) as part of the regulatory process.

    click here to find a list of Aciclovir suppliers with Written Confirmation (WC) on PharmaCompass.

    Aciclovir NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Aciclovir as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Aciclovir API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Aciclovir as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Aciclovir and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Aciclovir NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Aciclovir suppliers with NDC on PharmaCompass.

    Aciclovir GMP

    Aciclovir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Aciclovir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aciclovir GMP manufacturer or Aciclovir GMP API supplier for your needs.

    Aciclovir CoA

    A Aciclovir CoA (Certificate of Analysis) is a formal document that attests to Aciclovir's compliance with Aciclovir specifications and serves as a tool for batch-level quality control.

    Aciclovir CoA mostly includes findings from lab analyses of a specific batch. For each Aciclovir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Aciclovir may be tested according to a variety of international standards, such as European Pharmacopoeia (Aciclovir EP), Aciclovir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aciclovir USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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