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1. Ici 66082
2. Ici-66082
3. Ici66082
4. Tenormin
5. Tenormine
1. 29122-68-7
2. Tenormin
3. Blokium
4. Myocord
5. Normiten
6. Prenormine
7. Tenormine
8. (rs)-atenolol
9. Duraatenolol
10. Betacard
11. Corotenol
12. Tenoblock
13. Atehexal
14. Betablok
15. Cuxanorm
16. Juvental
17. Selobloc
18. Antipressan
19. Atcardil
20. Atenblock
21. Evitocor
22. Farnormin
23. Internolol
24. Normalol
25. Premorine
26. Prenolol
27. Tenoprin
28. Tensimin
29. Vascoten
30. Vericordin
31. Alinor
32. Anselol
33. Atecard
34. Atendol
35. Atenet
36. Atenil
37. Atereal
38. Aterol
39. Hipres
40. Hypoten
41. Ibinolo
42. Lotenal
43. Oraday
44. Serten
45. Stermin
46. Tenidon
47. Tenolol
48. Tredol
49. Uniloc
50. Wesipin
51. Altol
52. Ateni
53. Noten
54. Xaten
55. Seles Beta
56. Apo-atenolol
57. Felo-bits
58. Lo-ten
59. Atenolin
60. Atenomel
61. Blocotenol
62. Cardaxen
63. Cardiopress
64. Jenatenol
65. Panapres
66. Plenacor
67. Servitenol
68. Tenobloc
69. Aircrit
70. Betasyn
71. Ormidol
72. Prinorm
73. Unibloc
74. Loten
75. Atenol Acis
76. Atenol Cophar
77. Atenol Fecofar
78. Atenol Heumann
79. Atenol Nordic
80. Atenol Quesada
81. Atenol Gador
82. Atenol Stada
83. Atenol-mepha
84. Atenol-wolff
85. Atenol Atid
86. Atenol Ct
87. Atenol Tika
88. Atenol Trom
89. Atenol Genericon
90. Betatop Ge
91. Atenol Von Ct
92. Atenol-ratiopharm
93. Atenol Al
94. Atenol Pb
95. Atenol Gnr
96. Atenol Msd
97. Atenol Nm Pharma
98. Scheinpharm Atenol
99. Atenol 1a Pharma
100. Atenololum
101. 2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
102. Tenormine [french]
103. (r,s)-atenolol
104. Atenololum [inn-latin]
105. Ici 66082
106. 2-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
107. Tenormin (tn)
108. Ici-66082
109. Novaten
110. 1-p-carbamoylmethylphenoxy-3-isopropylamino-2-propanol
111. Ici 66,082
112. 2-[4-(2-hydroxy-3-isopropylaminopropoxy)phenyl]acetamide
113. 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
114. 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide
115. 2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetamide
116. Benzeneacetamide, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
117. C07ab03
118. Chembl24
119. Duratenol
120. Nsc-757832
121. Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-
122. 50vv3vw0ti
123. Mls000069622
124. Chebi:2904
125. Atenolol Bp
126. 60966-51-0
127. Smr000036768
128. Atenol
129. 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
130. Acetamide, 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)-
131. Teno-basan
132. Neatenol
133. Tensotin
134. Atcard
135. Dl-atenolol
136. Ccris 4196
137. (+/-)-atenolol
138. Hsdb 6526
139. Sr-01000000159
140. Einecs 249-451-7
141. Einecs 262-544-7
142. Mfcd00057645
143. Unii-50vv3vw0ti
144. Brn 2739235
145. 2-(4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl)acetamide
146. Artrenolol
147. 2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)ethanamide
148. 4-(2-hydroxy-3-[(1-methylethyl)amino]propoxy)benzeneacetamide
149. 2-(4-(2-hydroxy-3-isopropylaminopropoxy)phenyl)acetamid
150. Phenyl)acetamide
151. Atenolol [usan:ban:inn:jan]
152. (y)-atenolol
153. Atenalol (rs)
154. Atenolol,(s)
155. (?)-atenolol
156. Atenolol [usan:usp:inn:ban:jan]
157. (a+/-)-atenolol
158. Tenoretic (salt/mix)
159. Atenolol (jan/usp)
160. Spectrum_001364
161. Atenolol [hsdb]
162. Atenolol [usan]
163. Atenolol [inn]
164. Atenolol [jan]
165. Atenolol [mi]
166. Atenolol [vandf]
167. Opera_id_1283
168. Spectrum2_001411
169. Spectrum3_001448
170. Spectrum4_000435
171. Spectrum5_001509
172. Atenolol [mart.]
173. Dsstox_cid_2628
174. Atenolol [usp-rs]
175. Atenolol [who-dd]
176. Atenolol [who-ip]
177. A 7655
178. Schembl4362
179. Dsstox_rid_76663
180. Dsstox_gsid_22628
181. Lopac0_000121
182. Oprea1_448775
183. Bspbio_002915
184. Gtpl548
185. Kbiogr_000790
186. Kbioss_001844
187. Mls001066372
188. Mls001074163
189. Mls001304038
190. Divk1c_000057
191. Spectrum1501127
192. Atenolol (jp17/usp/inn)
193. Spbio_001482
194. Atenolol [orange Book]
195. Atenolol [ep Monograph]
196. Atenolol [usp Impurity]
197. Atenolol [usp Monograph]
198. Dtxsid2022628
199. Bdbm25753
200. Hms500c19
201. Kbio1_000057
202. Kbio2_001844
203. Kbio2_004412
204. Kbio2_006980
205. Kbio3_002415
206. Metkimkyrpqlgs-uhfffaoysa-
207. Polycap Component Atenolol
208. Atenololum [who-ip Latin]
209. Ninds_000057
210. S-atenolol-d7 (iso-propyl-d7)
211. 2-{4-[2-hydroxy-3-(isopropylamino)propoxy]-phenyl}acetamide
212. Hms1569l13
213. Hms1921h09
214. Hms2090i19
215. Hms2092d19
216. Hms2233e06
217. Hms3259k08
218. Hms3260i04
219. Hms3266k13
220. Hms3369b14
221. Hms3369d20
222. Hms3369p20
223. Hms3411g21
224. Hms3675g21
225. Hms3886g03
226. Pharmakon1600-01501127
227. ( Inverted Question Mark)-atenolol
228. Tenoretic Component Atenolol
229. Bcp12899
230. Atenolol 1.0 Mg/ml In Acetonitrile
231. Atenolol, >=98% (tlc), Powder
232. Tox21_302426
233. Tox21_500121
234. 2-[4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide
235. Atenolol 100 Microg/ml In Methanol
236. Bbl009276
237. Ccg-39010
238. Geo-03413
239. Nsc757832
240. S4817
241. Stk528649
242. Akos005111050
243. Atenolol Component Of Tenoretic
244. Ac-8245
245. Atenolol, Analytical Reference Material
246. Db00335
247. Ks-5341
248. Lp00121
249. Nc00548
250. Nsc 757832
251. Sdccgsbi-0050109.p004
252. Idi1_000057
253. Mrf-0000571
254. Ncgc00015007-06
255. Ncgc00015007-07
256. Ncgc00015007-08
257. Ncgc00015007-09
258. Ncgc00015007-10
259. Ncgc00015007-11
260. Ncgc00015007-13
261. Ncgc00015007-24
262. Ncgc00024566-03
263. Ncgc00024566-04
264. Ncgc00024566-05
265. Ncgc00024566-06
266. Ncgc00024566-07
267. Ncgc00255122-01
268. Ncgc00260806-01
269. Ba166036
270. Hy-17498
271. Sbi-0050109.p003
272. Cas-29122-68-7
273. Db-072177
274. Db-079552
275. Eu-0100121
276. Ft-0662315
277. Ft-0662316
278. Ft-0693045
279. 2-(4-(2-hydroxy-3-(isopropylamino)propoxy)
280. Bim-0050109.0001
281. D00235
282. O10469
283. Ab00052208-13
284. Ab00052208-15
285. Ab00052208_16
286. 122a687
287. L000116
288. Q411325
289. Q-200656
290. Sr-01000000159-2
291. Sr-01000000159-4
292. Sr-01000000159-5
293. Sr-01000000159-8
294. Brd-a20239487-001-02-5
295. Brd-a20239487-001-15-7
296. Atenolol, European Pharmacopoeia (ep) Reference Standard
297. Z1541638518
298. Atenolol, United States Pharmacopeia (usp) Reference Standard
299. (+)-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
300. (rs)-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
301. 2-(p-(hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide
302. (+/-)-4-(2-hydroxy-3-[(1-methylethyl)amino]propoxy)benzeneacetamide
303. 2-(4-{[(2s)-2-hydroxy-3-(propan-2-ylamino)propyl]oxy}phenyl)acetamide
304. Atenolol, Pharmaceutical Secondary Standard; Certified Reference Material
305. 2-(p-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide (racemate)
306. 2-[4-({(2r)-2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenyl]acetamide
307. Atenolol Solution, 1.0 Mg/ml In Acetonitrile, Ampule Of 1 Ml, Certified Reference Material
308. 106020-65-9
| Molecular Weight | 266.34 g/mol |
|---|---|
| Molecular Formula | C14H22N2O3 |
| XLogP3 | 0.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 8 |
| Exact Mass | 266.16304257 g/mol |
| Monoisotopic Mass | 266.16304257 g/mol |
| Topological Polar Surface Area | 84.6 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 263 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
| 1 of 4 | |
|---|---|
| Drug Name | Atenolol |
| PubMed Health | Atenolol |
| Drug Classes | Antianginal, Antiarrhythmic, Group II, Antihypertensive, Antimigraine, Cardiovascular Agent |
| Drug Label | Atenolol, a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]-. The molecular formula is C14H22N2O3 and its structural |
| Active Ingredient | Atenolol |
| Dosage Form | Tablet |
| Route | Oral |
| Strength | 25mg; 100mg; 50mg |
| Market Status | Prescription |
| Company | Ipca Labs; Mutual Pharm; Teva; Ipr; Aurobindo Pharma; Sun Pharm Inds; Zydus Pharms Usa; Northstar Hlthcare; Unique Pharm Labs; Sandoz; Mylan; Dava Pharms |
| 2 of 4 | |
|---|---|
| Drug Name | Tenormin |
| PubMed Health | Atenolol |
| Drug Classes | Antianginal, Antiarrhythmic, Group II, Antihypertensive, Antimigraine, Cardiovascular Agent |
| Drug Label | TENORMIN (atenolol), a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]-. The molecular and structural formulas are: |
| Active Ingredient | Atenolol |
| Dosage Form | Tablet |
| Route | Oral |
| Strength | 25mg; 100mg; 50mg |
| Market Status | Prescription |
| Company | Astrazeneca |
| 3 of 4 | |
|---|---|
| Drug Name | Atenolol |
| PubMed Health | Atenolol |
| Drug Classes | Antianginal, Antiarrhythmic, Group II, Antihypertensive, Antimigraine, Cardiovascular Agent |
| Drug Label | Atenolol, a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]-. The molecular formula is C14H22N2O3 and its structural |
| Active Ingredient | Atenolol |
| Dosage Form | Tablet |
| Route | Oral |
| Strength | 25mg; 100mg; 50mg |
| Market Status | Prescription |
| Company | Ipca Labs; Mutual Pharm; Teva; Ipr; Aurobindo Pharma; Sun Pharm Inds; Zydus Pharms Usa; Northstar Hlthcare; Unique Pharm Labs; Sandoz; Mylan; Dava Pharms |
| 4 of 4 | |
|---|---|
| Drug Name | Tenormin |
| PubMed Health | Atenolol |
| Drug Classes | Antianginal, Antiarrhythmic, Group II, Antihypertensive, Antimigraine, Cardiovascular Agent |
| Drug Label | TENORMIN (atenolol), a synthetic, beta1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4 -[2'-hydroxy-3'-[(1- methylethyl) amino] propoxy]-. The molecular and structural formulas are: |
| Active Ingredient | Atenolol |
| Dosage Form | Tablet |
| Route | Oral |
| Strength | 25mg; 100mg; 50mg |
| Market Status | Prescription |
| Company | Astrazeneca |
Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Sympatholytics
National Library of Medicine's Medical Subject Headings online file (MeSH, 1999)
Atenolol has been used with good results alone or in conjunction with a benzodiazepine in the management of acute alcohol withdrawal in a limited number of patients.
McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1739
Atenolol ... /is/ indicated in the treatment of classic angina pectoris, also referred to as "effort-associated angina". /Included in US product labeling/
MICROMEDEX Thomson Health Care. USPDI - Drug Information for the Health Care Professional. 23rd ed. Volume 1. MICROMEDEX Thomson Health Care, Greenwood Village, CO. 2003. Content Reviewed and Approved by the U.S. Pharmacopeial Convention, Inc., p. 550
Atenolol /is/ used in the treatment of mitral value prolapse syndrome. /NOT included in US product labeling/
MICROMEDEX Thomson Health Care. USPDI - Drug Information for the Health Care Professional. 23rd ed. Volume 1. MICROMEDEX Thomson Health Care, Greenwood Village, CO. 2003. Content Reviewed and Approved by the U.S. Pharmacopeial Convention, Inc., p. 551
For more Therapeutic Uses (Complete) data for ATENOLOL (12 total), please visit the HSDB record page.
Atenolol should be used with caution and in reduced dosage in patients with impaired renal function, especially when creatinine clearance is less than 35 ml/minute per 1.73 sq m. ... Patients receiving atenolol after hemodialysis /should/ be administered the drug under close supervision in a hospital setting, since marked hypotension may occur.
McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1742
Atenolol is contraindicated in patients with sinus bradycardia, AV block greater than first degree, cardiogenic shock, and overt cardiac failure.
McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1742
Atenolol should be used with caution in patients undergoing major surgery involving general anesthesia. The necessity of withdrawing beta-adrenergic blocking therapy prior to major surgery is controversial. Severe, protracted hypotension and difficulty in restarting or maintaining a heart beat have occurred during surgery in some patients who have received beta-adrenergic blocking agents.
McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1742
Abrupt withdrawal of atenolol may exacerbate angina symptoms and/or precipitate myocardial infarction and venticular arrhythmias in patients with coronary artery disease, or may precipitate thyroid storm in patients with thyrotoxicosis. Therefore, patients receiving atenolol (especially those with ischemic heart disease) should be warned not to interrupt or discontinue therapy without consulting their physician.
McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 2003. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 2003 (Plus Supplements)., p. 1741
For more Drug Warnings (Complete) data for ATENOLOL (12 total), please visit the HSDB record page.
**Indicated** for: 1) Management of hypertension alone and in combination with other antihypertensives. 2) Management of angina pectoris associated with coronary atherosclerosis. 3) Management of acute myocardial infarction in hemodynamically stable patients with a heart rate greater than 50 beats per minutes and a systolic blood pressure above 100 mmHg. **Off-label** uses include: 1) Secondary prevention of myocardial infarction. 2) Management of heart failure. 3) Management of atrial fibrillation. 4) Management of supraventricular tachycardia. 5) Management of ventricular arrythmias such as congenital long-QT and arrhythmogenic right ventricular cardiomyopathy. 6) Management of symptomatic thyrotoxicosis in combination with [methimazole]. 7) Prophylaxis of migraine headaches. 8) Management of alcohol withdrawal.
FDA Label
Atenolol is a cardio-selective beta-blocker and as such exerts most of its effects on the heart. It acts as an antagonist to sympathetic innervation and prevents increases in heart rate, electrical conductivity, and contractility in the heart due to increased release of norepinephrine from the peripheral nervous system. Together the decreases in contractility and rate produce a reduction in cardiac output resulting in a compensatory increase in peripheral vascular resistance in the short-term. This response later declines to baseline with long-term use of atenolol. More importantly, this reduction in the work demanded of the myocardium also reduces oxygen demand which provides therapeutic benefit by reducing the mismatch of oxygen supply and demand in settings where coronary blood flow is limited, such as in coronary atherosclerosis. Reducing oxygen demand, particularly due to exercise, can reduce the frequency of angina pectoris symptoms and potentially improve survival of the remaining myocardium after myocardial infarction. The decrease in rate of sinoatrial node potentials, electrical conduction, slowing of potentials traveling through the atrioventricular node, and reduced frequency of ectopic potentials due to blockade of adrenergic beta receptors has led to benefit in arrhythmic conditions such as atrial fibrillation by controlling the rate of action potential generation and allowing for more effective coordinated contractions. Since a degree of sympathetic activity is necessary to maintain cardiac function, the reduced contractility induced by atenolol may precipitate or worsen heart failure, especially during volume overload. The effects of atenolol on blood pressure have been established, although it is less effective than alternative beta-blockers, but the mechanism has not yet been characterized. As a 1 selective drug, it does not act via the vasodilation produced by non-selective agents. Despite this there is a sustained reduction in peripheral vascular resistance, and consequently blood pressure, alongside a decrease in cardiac output. It is thought that atenolol's antihypertensive activity may be related to action on the central nervous system (CNS) or it's inhibition of the renin-aldosterone-angiotensin system rather than direct effects on the vasculature. Atenolol produces CNS effects similar to other beta-blockers, but does so to a lesser extent due to reduces ability to cross the blood-brain barrier. It has the potential to produce fatigue, depression, and sleep disturbances such as nightmares or insomnia. The exact mechanisms behind these have not been characterized but their occurrence must be considered as they represent clinically relevant adverse effects. Atenolol exerts some effects on the respiratory system although to a much lesser extent than non-selective beta-blockers. Interaction with 2 receptors in the airways can produce bronchoconstriction by blocking the relaxation of bronchial smooth muscle mediated by the sympathetic nervous system. The same action can interfere with -agonist therapies used in asthma and chronic obstructive pulmonary disease. Unlike some other beta-blocker drugs, atenolol does not have intrinsic sympathomimetic or membrane stabilizing activity nor does it produce changes in glycemic control.
Anti-Arrhythmia Agents
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolong
