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Details:
Keytruda (pembrolizumab) in combination with Padcev (enfortumab vedotin-ejfv) is approved by USFDA for the first-line treatment of adult patients with locally advanced or metastatic urothelial cancer.
Lead Product(s): Pembrolizumab,Enfortumab Vedotin
Therapeutic Area: Oncology Brand Name: Keytruda
Study Phase: ApprovedProduct Type: Large molecule
Recipient: Merck & Co
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 26, 2024
Lead Product(s) : Pembrolizumab,Enfortumab Vedotin
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Merck & Co
Deal Size : Not Applicable
Deal Type : Not Applicable
Merck Receives Positive EU CHMP Opinion for KEYTRUDA® Plus Padcev® in Urothelial Carcinoma
Details : Keytruda (pembrolizumab) in combination with Padcev (enfortumab vedotin-ejfv) is approved by USFDA for the first-line treatment of adult patients with locally advanced or metastatic urothelial cancer.
Brand Name : Keytruda
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 26, 2024
Details:
Durveqtix (fidanacogene elaparvovec) is an adeno-associated viral (AAV) vector-based gene therapy approved for the treatment of adults with moderately severe to severe hemophilia B.
Lead Product(s): Fidanacogene elaparvovec
Therapeutic Area: Genetic Disease Brand Name: Durveqtix
Study Phase: ApprovedProduct Type: Cell and Gene therapy
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 25, 2024
Lead Product(s) : Fidanacogene elaparvovec
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
European Commission Approves Pfizer’s DURVEQTIX® Gene Therapy for Hemophilia B
Details : Durveqtix (fidanacogene elaparvovec) is an adeno-associated viral (AAV) vector-based gene therapy approved for the treatment of adults with moderately severe to severe hemophilia B.
Brand Name : Durveqtix
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 25, 2024
Details:
PF-07055480 (giroctocogene fitelparvovec) a novel, investigational gene therapy containing modified B-domain deleted human coagulation FVIII gene. It is being investigated for treating hemophilia A.
Lead Product(s): Giroctocogene Fitelparovec
Therapeutic Area: Genetic Disease Brand Name: PF-07055480
Study Phase: Phase IIIProduct Type: Cell and Gene therapy
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 24, 2024
Lead Product(s) : Giroctocogene Fitelparovec
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Pfizer Announces Topline Results from Phase 3 Hemophilia A Gene Therapy Trial
Details : PF-07055480 (giroctocogene fitelparvovec) a novel, investigational gene therapy containing modified B-domain deleted human coagulation FVIII gene. It is being investigated for treating hemophilia A.
Brand Name : PF-07055480
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 24, 2024
Details:
VLA15, an alum-adjuvanted formulation administered intramuscularly, is a vaccine candidate currently undergoing clinical development for the treatment of Lyme disease.
Lead Product(s): VLA15
Therapeutic Area: Infections and Infectious Diseases Brand Name: VLA15
Study Phase: Phase IIIProduct Type: Vaccine
Recipient: Valneva
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 17, 2024
Lead Product(s) : VLA15
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Recipient : Valneva
Deal Size : Not Applicable
Deal Type : Not Applicable
VALOR Trial: Valneva and Pfizer Announce Primary Vaccination Series Completion
Details : VLA15, an alum-adjuvanted formulation administered intramuscularly, is a vaccine candidate currently undergoing clinical development for the treatment of Lyme disease.
Brand Name : VLA15
Molecule Type : Vaccine
Upfront Cash : Not Applicable
July 17, 2024
Details:
PF-06882961 (danuglipron) is an oral GLP-1R agonist smalll molecule candidate, which is being evaluated for the treatment of adults with obesity and without type 2 diabetes.
Lead Product(s): Danuglipron
Therapeutic Area: Nutrition and Weight Loss Brand Name: PF-06882961
Study Phase: Phase IIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable July 11, 2024
Lead Product(s) : Danuglipron
Therapeutic Area : Nutrition and Weight Loss
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Pfizer Advances Once-Daily Oral GLP-1 Agonist Danuglipron Development
Details : PF-06882961 (danuglipron) is an oral GLP-1R agonist smalll molecule candidate, which is being evaluated for the treatment of adults with obesity and without type 2 diabetes.
Brand Name : PF-06882961
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 11, 2024
Details:
Evotec will collaborate with Pfizer to discover, and research potential new first-in-class therapeutic approaches for the treatment of metabolic and infectious diseases.
Lead Product(s): Undisclosed
Therapeutic Area: Genetic Disease Brand Name: Undisclosed
Study Phase: DiscoveryProduct Type: Undisclosed
Recipient: Evotec
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration July 10, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Genetic Disease
Highest Development Status : Discovery
Recipient : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
Evotec and Pfizer Collaborate to Advance Drug Discovery in France
Details : Evotec will collaborate with Pfizer to discover, and research potential new first-in-class therapeutic approaches for the treatment of metabolic and infectious diseases.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
July 10, 2024
Details:
Comirnaty JN.1 (Omi JN.1), a COVID-19 mRNA vaccine has achieved positive CHMP opinion by EMA for Omicron JN.1 lineage of SARS-CoV-2 infection in individuals 6 months of age and older.
Lead Product(s): BNT162b2
Therapeutic Area: Infections and Infectious Diseases Brand Name: Comirnaty JN.1
Study Phase: Phase IIIProduct Type: Vaccine
Recipient: BioNTech
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 27, 2024
Lead Product(s) : BNT162b2
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Recipient : BioNTech
Deal Size : Not Applicable
Deal Type : Not Applicable
Pfizer and BioNTech Get Positive CHMP Opinion for Omicron COVID-19 Vaccine
Details : Comirnaty JN.1 (Omi JN.1), a COVID-19 mRNA vaccine has achieved positive CHMP opinion by EMA for Omicron JN.1 lineage of SARS-CoV-2 infection in individuals 6 months of age and older.
Brand Name : Comirnaty JN.1
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 27, 2024
Details:
Elrexfio (elranatamab) is an off-the-shelf, BCMA-CD3-directed bispecific antibody immunotherapy. It is being evaluated for the treatment of relapsed and refractory multiple myeloma.
Lead Product(s): Elranatamab
Therapeutic Area: Oncology Brand Name: Elrexfio
Study Phase: Phase IIProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 15, 2024
Pfizer's Elrexfio Shows Positive Results in Phase 2 RRMM Study
Details : Elrexfio (elranatamab) is an off-the-shelf, BCMA-CD3-directed bispecific antibody immunotherapy. It is being evaluated for the treatment of relapsed and refractory multiple myeloma.
Brand Name : Elrexfio
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 15, 2024
Details:
The collaboration with Pfizer to evaluate atirmociclib, selective-CDK4 inhibitor, in combination with RLY-2608 and fulvestrant in patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.
Lead Product(s): RLY-2608,Atirmociclib,Fulvestrant
Therapeutic Area: Oncology Brand Name: RLY-2608
Study Phase: PreclinicalProduct Type: Small molecule
Recipient: Relay Therapeutics
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration June 05, 2024
Lead Product(s) : RLY-2608,Atirmociclib,Fulvestrant
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Relay Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Relay Therapeutics, Pfizer to Collaborate on Atirmociclib and RLY-2608 Clinical Trial
Details : The collaboration with Pfizer to evaluate atirmociclib, selective-CDK4 inhibitor, in combination with RLY-2608 and fulvestrant in patients with PI3Kα-mutated, HR+, HER2- metastatic breast cancer.
Brand Name : RLY-2608
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 05, 2024
Details:
Tivdak (tisotumab vedotin) is an ADC that acts as coagulation factor III binding agent & tubulin inhibitor. It is being evaluated for the treatment of Head and Neck Squamous Cell Carcinoma.
Lead Product(s): Tisotumab Vedotin,Pembrolizumab,Carboplatin
Therapeutic Area: Oncology Brand Name: Tivdak
Study Phase: Phase IIProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 03, 2024
Lead Product(s) : Tisotumab Vedotin,Pembrolizumab,Carboplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Tisotumab Vedotin Phase 2 Shows Antitumor Activity in Recurrent Head and Neck Cancer
Details : Tivdak (tisotumab vedotin) is an ADC that acts as coagulation factor III binding agent & tubulin inhibitor. It is being evaluated for the treatment of Head and Neck Squamous Cell Carcinoma.
Brand Name : Tivdak
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 03, 2024
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : INJ
Dosage Strength : 500mg/10ml
Packaging : 10X10mg/10ml
Brand Name : Fluroblastin
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : CAP
Dosage Strength : 250mg
Packaging : 90X1mg
Brand Name : Olbetam
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : INJ
Dosage Strength : 25mg
Packaging : 1X5mg/ml
Brand Name : Prostin VR
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : POI
Dosage Strength : 20mcg
Packaging : 1X1mcg
Brand Name : Caverject 20ug
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : FCT
Dosage Strength : 5mg
Packaging : 30X1mg
Brand Name : Caduet 5mg/40mg
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : FCT
Dosage Strength : 5mg
Packaging : 30X1mg
Brand Name : Caduet 5mg/80mg
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : FCT
Dosage Strength : 10mg
Packaging : 30X1mg
Brand Name : Caduet 10mg/80mg
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : INF
Dosage Strength : 100mg/30ml
Packaging : 30X1mg/30ml
Brand Name : ERAXIS 100 mg
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Antithymocyte immunoglobulin (Equine)
Dosage Form : INJ
Dosage Strength : 50mg/ml
Packaging : 5X5mg/ml
Brand Name : Atgam
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
Regulatory Info : Originator
Registration Country : South Africa
Dosage Form : FCT
Dosage Strength : 5mg
Packaging : 60X1mg
Brand Name : Eliquis 2.5 mg
Approval Date :
Application Number :
Regulatory Info : Originator
Registration Country : South Africa
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