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Find Approved Gastroenterology Drugs in Clinical Development

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            Lead Product(s): Bismuth Subsalicylate

            Therapeutic Area: Gastroenterology Product Name: Undisclosed

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Arcadia Consumer Healthcare

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Acquisition March 20, 2020

            Details:

            Acquisition further strengthens Arcadia's consumer healthcare product portfolio.

            Virtual BoothA global leader in antibiotics.

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            Lead Product(s): Pantoprazole Sodium

            Therapeutic Area: Gastroenterology Product Name: Undisclosed

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Civica Rx

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration November 02, 2020

            Details:

            Sandoz has shipped pantoprazole sodium for injection, 40 mg to Civica Rx to supply the hospitals it serves as part of a multiyear collaboration to help reduce supply shortages, with several other medicines on the way before the end of the year.

            Virtual BoothA global leader in antibiotics.

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            Lead Product(s): Naldemedine Tosylate

            Therapeutic Area: Gastroenterology Product Name: Rizmoic

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 30, 2020

            Details:

            Based on Phase 3 trial data, Rizmoic has been shown to increase the frequency of bowel movements compared to placebo in patients either with cancer or chronic non-cancer pain who had previously received laxative treatment.

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            Lead Product(s): Prednisone

            Therapeutic Area: Gastroenterology Product Name: Undisclosed

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 23, 2020

            Details:

            Prednisone is bioequivalent and therapeutically equivalent to the Reference Listed Drug (RLD), Deltasone Tablets, 2.5 mg and 5 mg, of Pharmacia and Upjohn Co.

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            Lead Product(s): Metoclopramide

            Therapeutic Area: Gastroenterology Product Name: Gimoti

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Eversana

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 26, 2020

            Details:

            Gimoti™ is a nasal spray launched for the relief of symptoms in adults with acute and recurrent diabetic gastroparesis. Product launch provides healthcare providers a novel treatment approach for patients suffering from symptoms of acute and recurrent diabetic gastroparesis.

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            Lead Product(s): Plecanatide

            Therapeutic Area: Gastroenterology Product Name: Trulance

            Highest Development Status: Approved Product Type: Peptide

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 22, 2020

            Details:

            Poster titled "The Impact of Plecanatide on Abdominal Pain in Patients with Chronic Idiopathic Constipation and Irritable Bowel Syndrome with Constipation: Analysis from Four Phase 3 Studies" at the The American College Of Gastroenterology 2020 Virtual Annual Meeting.

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            Lead Product(s): Tofacitinib Citrate

            Therapeutic Area: Gastroenterology Product Name: Undisclosed

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 19, 2020

            Details:

            Zydus Cadila has received tentative approval from US Food and Drug Administration (FDA) to market tofacitinib extended-release tablets, 11 mg.

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            Lead Product(s): Prebiotics

            Therapeutic Area: Gastroenterology Product Name: Goodgut

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: PanTheryx

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Acquisition October 14, 2020

            Details:

            The acquisition adds a high-quality prebiotic to the PanTheryx product lines that already include bovine colostrum for digestive and immune human health.

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            Lead Product(s): Vedolizumab

            Therapeutic Area: Gastroenterology Product Name: Entyvio

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 12, 2020

            Details:

            Interim analysis from VISIBLE OLE study showed long-term findings consistent with the known safety profile of vedolizumab with maintained rates of clinical remission and corticosteroid-free clinical remission.

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            Lead Product(s): Ustekinumab

            Therapeutic Area: Gastroenterology Product Name: Stelara

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 12, 2020

            Details:

            More than half of the patients with moderately to severely active CD who were randomized to subcutaneous STELARA every 8 weeks and continued to receive this dosage in the LTE study maintained clinical response3 and remission through five years of treatment.

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