CSBio CSBio

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molecule","productStatus":"Biosimilar","date":"April 2023","url1":"","url2":"","graph1":"Large molecule","graph2":"Mabwell"},{"orgOrder":0,"company":"Zydus Lifesciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Zydus Lifesciences Gets Final Approval from The US FDA to Market Estradiol Transdermal System","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Approved","country":"INDIA","productType":"Small molecule","productStatus":"Approved","date":"April 2023","url1":"","url2":"","graph1":"Small molecule","graph2":"Zydus Lifesciences"},{"orgOrder":0,"company":"Ferring Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Ferring Announces Positive Topline Phase 3 Results for SI-6603, an Investigational Treatment for Lumbar Disc Herniation","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Approved","country":"SWITZERLAND","productType":"Large molecule","productStatus":"Approved","date":"May 2023","url1":"","url2":"","graph1":"Large molecule","graph2":"Ferring Pharmaceuticals"},{"orgOrder":0,"company":"EffRx Pharmaceuticals","sponsor":"Abiogen Pharma S.p.A","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"Abiogen Pharma Completes the Acquisition of EffRx Pharmaceuticals","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Approved","country":"SWITZERLAND","productType":"Small molecule","productStatus":"Approved","date":"May 2023","url1":"","url2":"","graph1":"Small molecule","graph2":"EffRx Pharmaceuticals"},{"orgOrder":0,"company":"Sanofi","sponsor":"CORONA remedies","pharmaFlowCategory":"D","amount":"$28.5 million","upfrontCash":"Undisclosed","newsHeadline":"CORONA Remedies Buys India's Ortho Brand Myoril","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Approved","country":"FRANCE","productType":"Small molecule","productStatus":"Approved","date":"June 2023","url1":"","url2":"","graph1":"Small molecule","graph2":"Sanofi"},{"orgOrder":0,"company":"EffRx Pharmaceuticals","sponsor":"Radius Health","pharmaFlowCategory":"D","amount":"Undisclosed","upfrontCash":"Undisclosed","newsHeadline":"EffRx Pharmaceuticals Signs Exclusive Licensing Agreement with Radius Health to Commercialize BINOSTO\u00ae in the United States","therapeuticArea":"Musculoskeletal","highestDevelopmentStatus":"Approved","country":"SWITZERLAND","productType":"Small molecule","productStatus":"Approved","date":"September 2023","url1":"","url2":"","graph1":"Small molecule","graph2":"EffRx Pharmaceuticals"}]

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            Details:

            Through the acquisition, Corona Remedies gains right for the leading muscle relaxant brand Myoril (thiocolchicoside) and its extensions such as Myoril Plus (ketoprofen and thiocolchicoside) to treat muscular pain.

            Lead Product(s): Thiocolchicoside

            Therapeutic Area: Musculoskeletal Product Name: Myoril

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: CORONA remedies

            Deal Size: $28.5 million Upfront Cash: Undisclosed

            Deal Type: Acquisition June 28, 2023

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            Details:

            By partnering with Bioiberica, ByHealth aims to capitalise on the untapped potential of new product development with native type II collagen and respond to the growing number of consumers looking to support their mobility with effective, convenient products across the country.

            Lead Product(s): Undenatured Type II Collagen

            Therapeutic Area: Musculoskeletal Product Name: Collavant n2

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: ByHealth

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership March 11, 2022

            Details:

            Bioiberica’s native (undenatured) type II collagen, Collavant® n2 (previously b2-Cool®) and the addition of Tendaxion® - a new brand for its tendon health ingredient.

            Lead Product(s): Chondroitin Sulfate

            Therapeutic Area: Musculoskeletal Product Name: CSbioactive

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 05, 2021

            Details:

            Apsen’s Motilex HA combines two leading ingredients, b-2Cool native type II collagen and Mobilee, patented ingredient that synergistically combines a high concentration of hyaluronic acid with polysaccharides and collagen, to effectively maintain joint function.

            Lead Product(s): Hyaluronic Acid,Type II Collagen

            Therapeutic Area: Musculoskeletal Product Name: Motilex HA

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Apsen

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Partnership April 26, 2021

            Details:

            Dr. Reddy's Laboratories has launched Succinylcholine Chloride Injection USP, 200 mg/10 mL (20 mg/mL), Multiple-Dose Vials a therapeutic equivalent generic version of Quelicin® (Succinylcholine Chloride) Injection, 20 mg/mL, approved by the USFDA.

            Lead Product(s): Succinylcholine Chloride

            Therapeutic Area: Musculoskeletal Product Name: Undisclosed

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 12, 2020

            Details:

            The study, conducted in a rabbit model of osteoarthritis, set out to evaluate the effects of b-2Cool native type II collagen in combination with CS b-Bioactive chondroitin sulphate, glucosamine hydrochloride and Mobilee® which is a rooster comb extract rich in hyaluronic acid.

            Lead Product(s): Undenatured Type II Collagen,Chondroitin Sulfate,Hyaluronic Acid

            Therapeutic Area: Musculoskeletal Product Name: Mobilee

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable September 07, 2020

            Details:

            B-2Cool (Bioiberica’s native type II collagen) is an innovative ingredient, has been shown in four scientific studies to help maintain good joint health at a very low daily dose.

            Lead Product(s): Undenatured Type II Collagen,Harpagophytum Procumbens Extract,Hyaluronic Acid

            Therapeutic Area: Musculoskeletal Product Name: Colnatur Forte

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable July 15, 2020

            Details:

            Under the agreement, EffRx will grant Radius an exclusive, royalty bearing license to Binosto (alendronate sodium), an effervescent tablet for oral solution indicated for osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis, in the US.

            Lead Product(s): Alendronate Sodium

            Therapeutic Area: Musculoskeletal Product Name: Binosto

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Radius Health

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement September 19, 2023

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            Details:

            Through the acquisition, Abiogen gets Effrx's Binosto (alendronate sodium), an effervescent tablet for the treatment of osteoporosis. It will allow Abiogen to continue developing on Effrx's bisphosphonates family of molecules that in the area of ​​osteoarticular metabolism.

            Lead Product(s): Alendronate Sodium

            Therapeutic Area: Musculoskeletal Product Name: Binosto

            Highest Development Status: Approved Product Type: Small molecule

            Partner/Sponsor/Collaborator: Abiogen Pharma S.p.A

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Acquisition May 29, 2023

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            SI-6603 (condoliase), which contains Condoliase as its active pharmaceutical ingredient, is intended to treat lumbar disc herniation via a single, direct intradiscal injection.

            Lead Product(s): Condoliase

            Therapeutic Area: Musculoskeletal Product Name: SI-6603

            Highest Development Status: Approved Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable May 26, 2023

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