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Also known as: 62893-20-3, Sodium cefoperazone, Cefoperazone sodium salt, Cefobid, Tomabef, T-1551
Molecular Formula
C25H26N9NaO8S2
Molecular Weight
667.7  g/mol
InChI Key
NCFTXMQPRQZFMZ-WERGMSTESA-M
FDA UNII
5FQG9774WD

Cefoperazone Sodium
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.
1 2D Structure

Cefoperazone Sodium

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2.1.2 InChI
InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/q;+1/p-1/t15-,16-,22-;/m1./s1
2.1.3 InChI Key
NCFTXMQPRQZFMZ-WERGMSTESA-M
2.1.4 Canonical SMILES
CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+]
2.1.5 Isomeric SMILES
CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)[O-].[Na+]
2.2 Other Identifiers
2.2.1 UNII
5FQG9774WD
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Cfobis

2. Cefobid

3. Cefoperazon

4. Cefoperazone

5. Cefoperazone Sodium Salt

6. Salt, Cefoperazone Sodium

7. Sodium Salt, Cefoperazone

8. Sodium, Cefoperazone

9. T 1551

10. T-1551

11. T1551

2.3.2 Depositor-Supplied Synonyms

1. 62893-20-3

2. Sodium Cefoperazone

3. Cefoperazone Sodium Salt

4. Cefobid

5. Tomabef

6. T-1551

7. Cp 52640-2

8. Cefoperazone (sodium Salt)

9. Cefoperazone (as Sodium)

10. 5fqg9774wd

11. Chebi:3494

12. Cp-52,640-2

13. Nsc-758173

14. 62893-20-3 (sodium)

15. Cp-526402

16. Cefobid (tn)

17. Cp-52640-2

18. Dsstox_cid_25874

19. Dsstox_rid_81192

20. Dsstox_gsid_45874

21. Sodium;(6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

22. Cefobis

23. 1094606-34-4

24. Cas-62893-20-3

25. Cefobid In Plastic Container

26. Einecs 263-751-5

27. T 1551

28. Unii-5fqg9774wd

29. Cefoperazin

30. Cefoneg

31. Cefoper

32. Cefoperazon-natrium

33. Ncgc00094952-01

34. Cefobid Sodium Salt

35. Sodium;(6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxy

36. Cefoperazone Sodium [usan:usp:jan]

37. Cefoperazone, Sodium Salt

38. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-(p-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

39. Schembl537680

40. Chembl1200482

41. Dtxsid6045874

42. Hy-b0210a

43. Cefoperazone Sodium [jan]

44. Cefoperazone Sodium (jp17/usp)

45. Cefoperazone Sodium [usan]

46. Cefoperazone Sodium [vandf]

47. Cefoperazone Sodium [mart.]

48. Tox21_111367

49. Cefoperazone Sodium [who-dd]

50. Mfcd07793331

51. Cefoperazone Sodium Salt [mi]

52. Akos015951266

53. Tox21_111367_1

54. Ccg-270350

55. Cs-5023

56. Nsc 758173

57. Cefoperazone Sodium [ep Impurity]

58. Cefoperazone Sodium [orange Book]

59. Ncgc00179599-03

60. 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-(((((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-, Monosodium Salt, (6r-(6alpha,7beta(r*)))-

61. Cefoperazone Sodium [ep Monograph]

62. Cefoperazone Sodium [usp Monograph]

63. C08112

64. D00918

65. Sulperazone Component Cefoperazone Sodium

66. A834072

67. Cefoperazone Sodium Component Of Sulperazone

68. Q27106107

69. Cefoperazone Sodium 100 Microg/ml In Acetonitrile:water

70. (6r,7r)-7-[[(2r)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

71. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-(p-hydroxyphenyl)acetamido-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

72. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

73. Sodium (6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-1h-tetrazol-5-ylthio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

74. Sodium 7-[[2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

75. Sodium(6r,7r)-7-((r)-2-(4-ethyl-2,3-dioxopiperazine-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 667.7 g/mol
Molecular Formula C25H26N9NaO8S2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count13
Rotatable Bond Count9
Exact Mass667.12434545 g/mol
Monoisotopic Mass667.12434545 g/mol
Topological Polar Surface Area274 Ų
Heavy Atom Count45
Formal Charge0
Complexity1250
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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ABOUT THIS PAGE

Looking for 62893-20-3 / Cefoperazone Sodium API manufacturers, exporters & distributors?

Cefoperazone Sodium manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Cefoperazone Sodium API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Cefoperazone Sodium manufacturer or Cefoperazone Sodium supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Cefoperazone Sodium manufacturer or Cefoperazone Sodium supplier.

PharmaCompass also assists you with knowing the Cefoperazone Sodium API Price utilized in the formulation of products. Cefoperazone Sodium API Price is not always fixed or binding as the Cefoperazone Sodium Price is obtained through a variety of data sources. The Cefoperazone Sodium Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Cefoperazone Sodium

Synonyms

62893-20-3, Sodium cefoperazone, Cefoperazone sodium salt, Cefobid, Tomabef, T-1551

Cas Number

62893-20-3

Unique Ingredient Identifier (UNII)

5FQG9774WD

About Cefoperazone Sodium

Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It may be used to treat Pseudomonas infections.

Cefoperazone Sodium Manufacturers

A Cefoperazone Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Cefoperazone Sodium, including repackagers and relabelers. The FDA regulates Cefoperazone Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Cefoperazone Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Cefoperazone Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Cefoperazone Sodium Suppliers

A Cefoperazone Sodium supplier is an individual or a company that provides Cefoperazone Sodium active pharmaceutical ingredient (API) or Cefoperazone Sodium finished formulations upon request. The Cefoperazone Sodium suppliers may include Cefoperazone Sodium API manufacturers, exporters, distributors and traders.

click here to find a list of Cefoperazone Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Cefoperazone Sodium USDMF

A Cefoperazone Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Cefoperazone Sodium active pharmaceutical ingredient (API) in detail. Different forms of Cefoperazone Sodium DMFs exist exist since differing nations have different regulations, such as Cefoperazone Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Cefoperazone Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Cefoperazone Sodium USDMF includes data on Cefoperazone Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Cefoperazone Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Cefoperazone Sodium suppliers with USDMF on PharmaCompass.

Cefoperazone Sodium JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Cefoperazone Sodium Drug Master File in Japan (Cefoperazone Sodium JDMF) empowers Cefoperazone Sodium API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Cefoperazone Sodium JDMF during the approval evaluation for pharmaceutical products. At the time of Cefoperazone Sodium JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Cefoperazone Sodium suppliers with JDMF on PharmaCompass.

Cefoperazone Sodium KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Cefoperazone Sodium Drug Master File in Korea (Cefoperazone Sodium KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Cefoperazone Sodium. The MFDS reviews the Cefoperazone Sodium KDMF as part of the drug registration process and uses the information provided in the Cefoperazone Sodium KDMF to evaluate the safety and efficacy of the drug.

After submitting a Cefoperazone Sodium KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Cefoperazone Sodium API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Cefoperazone Sodium suppliers with KDMF on PharmaCompass.

Cefoperazone Sodium CEP

A Cefoperazone Sodium CEP of the European Pharmacopoeia monograph is often referred to as a Cefoperazone Sodium Certificate of Suitability (COS). The purpose of a Cefoperazone Sodium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Cefoperazone Sodium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Cefoperazone Sodium to their clients by showing that a Cefoperazone Sodium CEP has been issued for it. The manufacturer submits a Cefoperazone Sodium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Cefoperazone Sodium CEP holder for the record. Additionally, the data presented in the Cefoperazone Sodium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Cefoperazone Sodium DMF.

A Cefoperazone Sodium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Cefoperazone Sodium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Cefoperazone Sodium suppliers with CEP (COS) on PharmaCompass.

Cefoperazone Sodium GMP

Cefoperazone Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Cefoperazone Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Cefoperazone Sodium GMP manufacturer or Cefoperazone Sodium GMP API supplier for your needs.

Cefoperazone Sodium CoA

A Cefoperazone Sodium CoA (Certificate of Analysis) is a formal document that attests to Cefoperazone Sodium's compliance with Cefoperazone Sodium specifications and serves as a tool for batch-level quality control.

Cefoperazone Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Cefoperazone Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Cefoperazone Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Cefoperazone Sodium EP), Cefoperazone Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Cefoperazone Sodium USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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