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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Halcion (triazolam) tablets are used on a short-term basis to treat insomnia (difficulty falling asleep or staying asleep). It works by slowing activity in the brain to allow sleep.
HETLIOZ® (tasimelteon), is a melatonin receptor agonist that is FDA approved for both Non-24-Hour Sleep-Wake Disorder (a serious, chronic circadian rhythm disorder) and nighttime sleep disturbances in Smith-Magenis Syndrome (SMS) in patients 16 years of age and older.
The improvement in sleep onset, sleep maintenance and daytime functioning seen with 50 mg daridorexant were sustained for up to 12 months. Importantly, long-term treatment with daridorexant was not associated with any tolerance or physical dependence.
QUVIVIQ (daridorexant) will be the first dual orexin receptor antagonist (DORA) available in Switzerland for the treatment of chronic insomnia disorder. QUVIVIQ reduces nocturnal hyperarousal to improve sleep (onset and maintenance) without nextmorning residual effects.
Under the agreement, Simcere will be granted an exclusive right to develop and commercialize daridorexant (ACT-541468) in the Greater China region (Mainland China, Hong Kong, and Macau), one of the world's largest pharmaceutical markets.
QUVIVIQ (daridorexant), is the first dual orexin receptor antagonist (DORA) to be available to patients in Italy and Germany for the treatment of chronic insomnia disorder.
On the study’s primary endpoint, Sunosi (solriamfetol) demonstrated statistically significant improvement in cognitive function compared to placebo as assessed by the change from baseline on the DSST RBANS (6.49 vs. 4.75, p=0.009), with an effect size of 0.36.
The study met both primary and secondary efficacy endpoint measures ACT-541468 (Daridorexant) significantly improved sTST from baseline compared to placebo at 28 days (p<0.001 for 50 mg, p=0.042 for 25 mg).
Under the terms of the Agreement, Entourage will manufacture the newly formulated suite of Irwin-branded line of softgels in five different varieties: CBD, THC and three additional formulations that include both THC and another cannabinoid.
MDsleep (cannabis sativa oil), also known as hemp seed oil, is a lightweight oil cold-pressed from the seeds of the Cannabis sativa plant. It’s been used for centuries in cooking, as well as topically to help with a wide range of skin concerns.