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Tru Niagen (nicotinamide riboside) demonstrated that oral supplementation with NR significantly increased NAD+ levels in NEVs and attenuated neurodegenerative biomarkers including Aβ42, a biomarker for Alzheimer’s disease (AD).
Tru Niagen (nicotinamide riboside) demonstrated that oral supplementation with NR significantly increased NAD+ levels in NEVs and attenuated neurodegenerative biomarkers including Aβ42, a biomarker for Alzheimer’s disease (AD).
Satylia, also called EnteroSatys in other markets, is a precision probiotic with a characterized mechanism of action at molecular level: it increases feelings of fullness thanks to the probiotic's protein ClpB that mimics the satiety hormone alpha-MSH.
Rhythm intends to use the net proceeds from this offering to advance global commercialization of IMCIVREE for obesity due to POMC, PCSK1 or LEPR deficiency and BBS, to advance clinical development of setmelanotide in hypothalamic obesity.
Proceeds will be used to fund the Company’s lead asset, Imcivree (setmelanotide acetate), and support intellectual property development, other commercial activities, and for general working capital purposes.
Imcivree (setmelanotide) also achieved a meaningful reduction in hunger scores. Consistent with prior clinical experience in other rare MC4R pathway diseases, setmelanotide was observed to be generally well tolerated.
IMCIVREE® (setmelanotide), a melanocortin-4 receptor (MC4R) agonist, for treatment of obesity and the control of hunger associated with genetically confirmed loss-of-function biallelic POMC.
Rhythm intends to use the proceeds from the Agreement and its cash on hand to support global commercialization efforts for IMCIVREE® (setmelanotide) and ongoing clinical development.
Tru Niagen®, featuring Niagen®, is one of the top-selling brands in the Vitamin B3 category on Amazon U.S. for boosting NAD+ levels. Supplementation with Niagen® is backed by 20 published and peer-reviewed clinical trials.
EleCare formulas are hypoallergenic and are used by infants and children who have severe food allergies or gastrointestinal (GI) disorders that require amino acid-based formulas.