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    Chemistry

    Click the arrow to open the dropdown
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    Also known as: 15687-27-1, 2-(4-isobutylphenyl)propanoic acid, Motrin, Brufen, Advil, Nuprin
    Molecular Formula
    C13H18O2
    Molecular Weight
    206.28  g/mol
    InChI Key
    HEFNNWSXXWATRW-UHFFFAOYSA-N
    FDA UNII
    WK2XYI10QM
    Ibuprofen
    A non-steroidal anti-inflammatory agent with analgesic, antipyretic, and anti-inflammatory properties
    Ibuprofen is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of ibuprofen is as a Cyclooxygenase Inhibitor.
    1 2D Structure

    Ibuprofen

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-[4-(2-methylpropyl)phenyl]propanoic acid
    2.1.2 InChI
    InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
    2.1.3 InChI Key
    HEFNNWSXXWATRW-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
    2.2 Other Identifiers
    2.2.1 UNII
    WK2XYI10QM
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Advil

    2. Alpha-methyl-4-(2-methylpropyl)benzeneacetic Acid

    3. Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)- Trimethylsilyl Ester

    4. Brufen

    5. Ibumetin

    6. Ibuprofen Zinc

    7. Ibuprofen, (+-)-isomer

    8. Ibuprofen, (r)-isomer

    9. Ibuprofen, (s)-isomer

    10. Ibuprofen, Aluminum Salt

    11. Ibuprofen, Calcium Salt

    12. Ibuprofen, Copper (2+) Salt

    13. Ibuprofen, Magnesium Salt

    14. Ibuprofen, Potassium Salt

    15. Ibuprofen, Sodium Salt

    16. Ibuprofen, Zinc Salt

    17. Ibuprofen-zinc

    18. Motrin

    19. Nuprin

    20. Rufen

    21. Salprofen

    22. Trauma Dolgit Gel

    23. Trauma-dolgit Gel

    2.3.2 Depositor-Supplied Synonyms

    1. 15687-27-1

    2. 2-(4-isobutylphenyl)propanoic Acid

    3. Motrin

    4. Brufen

    5. Advil

    6. Nuprin

    7. Nurofen

    8. Medipren

    9. Dolgit

    10. Liptan

    11. 2-[4-(2-methylpropyl)phenyl]propanoic Acid

    12. Anflagen

    13. Buburone

    14. Butylenin

    15. Ibumetin

    16. Ibuprocin

    17. Ebufac

    18. Lamidon

    19. Rufen

    20. Mynosedin

    21. Apsifen

    22. Epobron

    23. Haltran

    24. Roidenin

    25. Trendar

    26. Adran

    27. Andran

    28. Bluton

    29. Nobfen

    30. Nobgen

    31. Pediaprofen

    32. Ibuprohm

    33. Nobfelon

    34. Brufort

    35. Burana

    36. Inabrin

    37. Pantrop

    38. Rebugen

    39. Suspren

    40. Tabalon

    41. (rs)-ibuprofen

    42. Anco

    43. Urem

    44. Ibu-slo

    45. Brufanic

    46. Napacetin

    47. Ibufen

    48. Ibuprin

    49. Profen

    50. Ibren

    51. Midol

    52. 4-isobutylhydratropic Acid

    53. Cap-profen

    54. Tab-profen

    55. Ibu-tab

    56. P-isobutylhydratropic Acid

    57. Proartinal

    58. Dibufen

    59. Optifen

    60. Ostofen

    61. Panafen

    62. Proflex

    63. Quadrax

    64. Uprofen

    65. Carol

    66. Dolgin

    67. Cobo

    68. (+-)-ibuprofen

    69. (+/-)-ibuprofen

    70. Artril 300

    71. 4-isobutyl-alpha-methylphenylacetic Acid

    72. Midol 200

    73. Duralbuprofen

    74. Butacortelone

    75. Amibufen

    76. Caldolor

    77. Dolgirid

    78. Ibuprofeno

    79. Ibuprofenum

    80. Lebrufen

    81. Seclodin

    82. Amelior

    83. Femadon

    84. Ibutid

    85. Inoven

    86. Alpha-(4-isobutylphenyl)propionic Acid

    87. Brufen Retard

    88. Ibu-attritin

    89. Dolo-dolgit

    90. Aches-n-pain

    91. Ip-82

    92. (+-)-p-isobutylhydratropic Acid

    93. Pedea

    94. Rd 13621

    95. Hydratropic Acid, P-isobutyl-

    96. Ib-100

    97. (4-isobutylphenyl)-alpha-methylacetic Acid

    98. 58560-75-1

    99. U-18,573

    100. P-isobutyl-2-phenylpropionic Acid

    101. (+-)-2-(p-isobutylphenyl)propionic Acid

    102. Alpha-(p-isobutylphenyl)propionic Acid

    103. 2-(4-isobutylphenyl)propionic Acid

    104. Alpha-p-isobutylphenylpropionic Acid

    105. (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic Acid

    106. Benzeneacetic Acid, .alpha.-methyl-4-(2-methylpropyl)-

    107. Chebi:5855

    108. Alpha-methyl-4-(2-methylpropyl)benzeneacetic Acid

    109. Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-

    110. M01ae01

    111. (+/-)-p-isobutylhydratropic Acid

    112. 2-(p-isobutylphenyl)propionic Acid

    113. Novoprofen

    114. Amersol

    115. Dolocyl

    116. Lidifen

    117. Mfcd00010393

    118. Paxofen

    119. Rafen

    120. Wk2xyi10qm

    121. Ibu

    122. Chembl521

    123. Ifen

    124. U-18573

    125. 2-(4-isobutyl-phenyl)-propionic Acid

    126. Nsc-256857

    127. Alpha-methyl-4-(isobutyl)phenylacetic Acid

    128. Mls000069733

    129. Balkaprofen

    130. Betaprofen

    131. Daiprophen

    132. Jenaprofen

    133. Antagil

    134. Antalfene

    135. Antarene

    136. Antiflam

    137. Artofen

    138. Bruflam

    139. Bufigen

    140. Bukrefen

    141. Buracaps

    142. Citalgan

    143. Combiflam

    144. Dansida

    145. Dentigoa

    146. Dignoflex

    147. Dolmaral

    148. Dolofen

    149. Dolofin

    150. Dolofort

    151. Dologel

    152. Dolomax

    153. Doloren

    154. Doltibil

    155. Dorival

    156. Duobrus

    157. Dysdolen

    158. Easifon

    159. Esprenit

    160. Exneural

    161. Femafen

    162. Femapirin

    163. Femidol

    164. Fenspan

    165. Fibraflex

    166. Gelufene

    167. Gynofug

    168. Ibubest

    169. Ibubeta

    170. Ibucasen

    171. Ibudolor

    172. Ibuflamar

    173. Ibugesic

    174. Ibuhexal

    175. Ibulagic

    176. Ibuleve

    177. Ibulgan

    178. Ibumerck

    179. Ibupirac

    180. Junifen

    181. Kratalgin

    182. Librofem

    183. Malafene

    184. Manypren

    185. Mensoton

    186. Neobrufen

    187. Nerofen

    188. Noalgil

    189. Nobafon

    190. Noritis

    191. Novadol

    192. Novogent

    193. Nuprilan

    194. Opturem

    195. Oralfene

    196. Ostarin

    197. Paduden

    198. Perofen

    199. R.d. 13621

    200. Ranofen

    201. Relcofen

    202. Rhinadvil

    203. Sadefen

    204. Salivia

    205. Sednafen

    206. Seklodin

    207. Seskafen

    208. Siyafen

    209. Solpaflex

    210. Sugafen

    211. Suprafen

    212. Syntofene

    213. Tatanal

    214. Unipron

    215. Alaxan

    216. Anafen

    217. Artril

    218. Brofen

    219. Bufeno

    220. Bupron

    221. Dolibu

    222. Dolven

    223. Duafen

    224. Emflam

    225. Eputex

    226. Faspic

    227. Fenbid

    228.&nb