[{"orgOrder":0,"company":"Sanofi","sponsor":"Nurix Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Discovery","graph3":"Sanofi","amount2":0.56999999999999995,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Immunology","amount2New":0.56999999999999995,"dosageForm":"Undisclosed","sponsorNew":"Sanofi \/ Sanofi","highestDevelopmentStatusID":"2","companyTruncated":"Sanofi \/ Sanofi"},{"orgOrder":0,"company":"Sanofi","sponsor":"Regeneron Pharmaceuticals","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"FRANCE","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Dupilumab","moa":"IL-4-alpha receptor","graph1":"Immunology","graph2":"Approved 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Find Immunology Clinical Drug Pipeline Developments & Deals by Sanofi

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Study Phase : Approved FDF

                          Recipient : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dupixent (dupilumab) is an interleukin-4/13 receptor alpha antagonist, indicated for the treatment of adult patients with bullous pemphigoid (BP).

                          Product Name : Dupixent

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          June 20, 2025

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Recipient : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          Lead Product(s) : Avapritinib

                          Therapeutic Area : Immunology

                          Study Phase : Approved FDF

                          Recipient : Blueprint Medicines

                          Deal Size : $9,500.0 million

                          Deal Type : Acquisition

                          Details : The acquisition includes a rare immunology disease medicine, Ayvakit/Ayvakyt (avapritinib), approved in the US and the EU, and a promising advanced and early-stage immunology pipeline.

                          Product Name : Ayvakit

                          Product Type : Other Small Molecule

                          Upfront Cash : $9,100.0 million

                          June 02, 2025

                          Lead Product(s) : Avapritinib

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Recipient : Blueprint Medicines

                          Deal Size : $9,500.0 million

                          Deal Type : Acquisition

                          Sanofi Company Banner

                          03

                          Lead Product(s) : SAR448501

                          Therapeutic Area : Immunology

                          Study Phase : Phase I

                          Recipient : Dren Bio

                          Deal Size : $1,900.0 million

                          Deal Type : Acquisition

                          Details : Sanofi acquired DR-0201, now named SAR448501, a targeted bispecific myeloid cell engager, has shown robust B-cell depletion in pre-clinical and early clinical studies.

                          Product Name : DR-0201

                          Product Type : Antibody

                          Upfront Cash : $600.0 million

                          May 27, 2025

                          Lead Product(s) : SAR448501

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Recipient : Dren Bio

                          Deal Size : $1,900.0 million

                          Deal Type : Acquisition

                          Sanofi Company Banner

                          04

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Study Phase : Preclinical

                          Recipient : C4X Discovery

                          Deal Size : $505.5 million

                          Deal Type : Licensing Agreement

                          Details : Under the licensing agreement, Sanofi is seeking to develop and commercialise an oral therapy for the treatment of inflammatory diseases such as psoriasis, psoriatic arthritis etc.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $8.3 million

                          May 27, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Recipient : C4X Discovery

                          Deal Size : $505.5 million

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          05

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Study Phase : Approved FDF

                          Recipient : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dupixent (dupilumab) is an approved monoclonal antibody works by inhibiting IL-4 and IL-13. It is indicated for the treatment in 12 years and older with chronic spontaneous urticaria.

                          Product Name : Dupixent

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 18, 2025

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Recipient : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          06

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Study Phase : Discovery

                          Recipient : Nurix Therapeutics

                          Deal Size : $570.0 million

                          Deal Type : Licensing Agreement

                          Details : Sanofi has exclusively licensed an undisclosed Nurix program targeting a previously undruggable transcription factor for autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : $55.0 million

                          April 02, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Recipient : Nurix Therapeutics

                          Deal Size : $570.0 million

                          Deal Type : Licensing Agreement

                          Sanofi Company Banner

                          07

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Study Phase : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dupixent (dupilumab) is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL4) and interleukin-13 (IL13) pathways.

                          Product Name : Dupixent

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 18, 2025

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          08

                          Lead Product(s) : Belumosudil

                          Therapeutic Area : Immunology

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Rezurock (belumosudil mesylate), a prescription medicine used to treat adults and children 12 years of age and older with chronic graft-versus-host disease, is launched in India.

                          Product Name : Rezurock

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 10, 2025

                          Lead Product(s) : Belumosudil

                          Therapeutic Area : Immunology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          09

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Study Phase : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dupixent (dupilumab) is an approved monoclonal antibody works by inhibiting IL-4 and IL-13. It is being investigated for the treatment in 12 years and older with chronic spontaneous urticaria.

                          Product Name : Dupixent

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 15, 2024

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          10

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Study Phase : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Dupixent (dupilumab) is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL4) and interleukin-13 (IL13) pathways.

                          Product Name : Dupixent

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 09, 2024

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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