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    Also known as: 133107-64-9, Insulin lispro (5.97 mg), Insulin-lispro, Dtxsid90157956
    Molecular Formula
    C257H389N65O77S6
    Molecular Weight
    5814  g/mol
    InChI Key
    WNRQPCUGRUFHED-DETKDSODSA-N
    Insulin Lispro
    Insulin that has been modified so that the B-chain contains a LYSINE at position 28 instead of a PROLINE and a PROLINE at position 29 instead of a LYSINE. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
    1 2D Structure

    Insulin Lispro

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4S)-4-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2R)-2-[[(2R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[(2-aminoacetyl)amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]-3-sulfanylpropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoyl]amino]-4-methylpentanoyl]amino]-5-[[(2S)-4-amino-1-[[(2S)-1-[[(2R)-1-[[(1S)-3-amino-1-carboxy-3-oxopropyl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-oxopentanoic acid;(4S)-4-[[2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-4-oxobutanoyl]amino]-5-oxopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-sulfanylpropanoyl]amino]acetyl]amino]-5-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-6-amino-1-[(2S)-2-[[(1S,2R)-1-carboxy-2-hydroxypropyl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
    2.1.2 InChI
    InChI=1S/C158H234N40O42S2.C99H155N25O35S4/c1-79(2)57-104(181-131(213)86(15)173-136(218)102(50-53-125(211)212)179-152(234)127(84(11)12)194-148(230)107(60-82(7)8)184-145(227)113(67-95-70-166-78-172-95)189-150(232)115(74-199)176-123(208)73-170-134(216)116(75-241)191-140(222)105(58-80(3)4)182-144(226)112(66-94-69-165-77-171-94)188-138(220)101(48-51-119(161)204)178-146(228)114(68-120(162)205)190-153(235)126(83(9)10)193-132(214)98(160)61-89-31-21-18-22-32-89)139(221)185-110(64-92-40-44-96(202)45-41-92)142(224)183-106(59-81(5)6)147(229)195-128(85(13)14)154(236)192-117(76-242)135(217)169-71-121(206)174-100(49-52-124(209)210)137(219)177-99(38-29-55-167-158(163)164)133(215)168-72-122(207)175-108(62-90-33-23-19-24-34-90)141(223)186-109(63-91-35-25-20-26-36-91)143(225)187-111(65-93-42-46-97(203)47-43-93)149(231)196-129(87(16)200)155(237)180-103(37-27-28-54-159)156(238)198-56-30-39-118(198)151(233)197-130(88(17)201)157(239)240;1-12-46(9)77(121-73(134)36-100)97(156)122-76(45(7)8)95(154)108-56(25-29-75(137)138)80(139)105-54(23-27-70(102)131)83(142)117-66(40-161)93(152)119-68(42-163)94(153)124-79(48(11)127)98(157)116-64(38-126)90(149)123-78(47(10)13-2)96(155)120-67(41-162)92(151)115-63(37-125)89(148)110-58(31-44(5)6)85(144)111-59(32-49-14-18-51(128)19-15-49)86(145)106-53(22-26-69(101)130)81(140)109-57(30-43(3)4)84(143)107-55(24-28-74(135)136)82(141)113-61(34-71(103)132)88(147)112-60(33-50-16-20-52(129)21-17-50)87(146)118-65(39-160)91(150)114-62(99(158)159)35-72(104)133/h18-26,31-36,40-47,69-70,77-88,98-118,126-130,199-203,241-242H,27-30,37-39,48-68,71-76,159-160H2,1-17H3,(H2,161,204)(H2,162,205)(H,165,171)(H,166,172)(H,168,215)(H,169,217)(H,170,216)(H,173,218)(H,174,206)(H,175,207)(H,176,208)(H,177,219)(H,178,228)(H,179,234)(H,180,237)(H,181,213)(H,182,226)(H,183,224)(H,184,227)(H,185,221)(H,186,223)(H,187,225)(H,188,220)(H,189,232)(H,190,235)(H,191,222)(H,192,236)(H,193,214)(H,194,230)(H,195,229)(H,196,231)(H,197,233)(H,209,210)(H,211,212)(H,239,240)(H4,163,164,167);14-21,43-48,53-68,76-79,125-129,160-163H,12-13,22-42,100H2,1-11H3,(H2,101,130)(H2,102,131)(H2,103,132)(H2,104,133)(H,105,139)(H,106,145)(H,107,143)(H,108,154)(H,109,140)(H,110,148)(H,111,144)(H,112,147)(H,113,141)(H,114,150)(H,115,151)(H,116,157)(H,117,142)(H,118,146)(H,119,152)(H,120,155)(H,121,134)(H,122,156)(H,123,149)(H,124,153)(H,135,136)(H,137,138)(H,158,159)/t86-,87+,88+,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,126-,127-,128-,129-,130-;46-,47-,48+,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,76-,77-,78-,79-/m00/s1
    2.1.3 InChI Key
    WNRQPCUGRUFHED-DETKDSODSA-N
    2.1.4 Canonical SMILES
    CCC(C)C(C(=O)NC(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CS)C(=O)NC(CS)C(=O)NC(C(C)O)C(=O)NC(CO)C(=O)NC(C(C)CC)C(=O)NC(CS)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)N)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CS)C(=O)NC(CC(=O)N)C(=O)O)NC(=O)CN.CC(C)CC(C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CS)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC2=CC=CC=C2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CC=C(C=C4)O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(=O)N5CCCC5C(=O)NC(C(C)O)C(=O)O)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC6=CN=CN6)NC(=O)C(CO)NC(=O)CNC(=O)C(CS)NC(=O)C(CC(C)C)NC(=O)C(CC7=CN=CN7)NC(=O)C(CCC(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(C(C)C)NC(=O)C(CC8=CC=CC=C8)N
    2.1.5 Isomeric SMILES
    CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)CN.C[C@H]([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC6=CN=CN6)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CS)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC8=CC=CC=C8)N)O
    2.2 Synonyms
    2.2.1 MeSH Synonyms

    1. 28(b)-lys-29(b)-pro-insulin

    2. 28(b)-lysine-29(b)-prolineinsulin

    3. Humalog

    4. Humalog Kwikpen

    5. Insulin, Lys(28b)-pro(29b)-

    6. Insulin, Lysyl(28b)-prolyl(28b)-

    7. Kwikpen, Humalog

    8. Lispro

    9. Lispro, Insulin

    10. Lyspro

    2.2.2 Depositor-Supplied Synonyms

    1. 133107-64-9

    2. Insulin Lispro (5.97 Mg)

    3. Insulin-lispro

    4. Dtxsid90157956

    2.3 Create Date
    2007-07-03
    3 Chemical and Physical Properties
    Molecular Weight 5814 g/mol
    Molecular Formula C257H389N65O77S6
    Hydrogen Bond Donor Count84
    Hydrogen Bond Acceptor Count89
    Rotatable Bond Count185
    Exact Mass5811.6913101 g/mol
    Monoisotopic Mass5809.6846004 g/mol
    Topological Polar Surface Area2310 Ų
    Heavy Atom Count405
    Formal Charge0
    Complexity13000
    Isotope Atom Count0
    Defined Atom Stereocenter Count52
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameHumalog
    PubMed HealthInsulin Lispro
    Drug ClassesAntidiabetic
    Drug LabelHumalog Mix50/50 [50% insulin lispro protamine suspension and 50% insulin lispro injection, (rDNA origin)] is a mixture of insulin lispro solution, a rapid-acting blood glucose-lowering agent and insulin lispro protamine suspension, an intermedi...
    Active IngredientInsulin lispro recombinant
    Dosage FormInjectable
    RouteInjection
    Strength100 units/ml
    Market StatusPrescription
    CompanyLilly

    2 of 2  
    Drug NameHumalog
    PubMed HealthInsulin Lispro
    Drug ClassesAntidiabetic
    Drug LabelHumalog Mix50/50 [50% insulin lispro protamine suspension and 50% insulin lispro injection, (rDNA origin)] is a mixture of insulin lispro solution, a rapid-acting blood glucose-lowering agent and insulin lispro protamine suspension, an intermedi...
    Active IngredientInsulin lispro recombinant
    Dosage FormInjectable
    RouteInjection
    Strength100 units/ml
    Market StatusPrescription
    CompanyLilly

    4.2 Drug Indication

    Insulin lispro is indicated to improve glycemic control in adults and children with diabetes mellitus.

    FDA Label

    Treatment of diabetes mellitus in adults.

    For the treatment of adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Insulin lispro Sanofi is also indicated for the initial stabilisation of diabetes mellitus.

    For the treatment of adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Liprolog is also indicated for the initial stabilisation of diabetes mellitus.

    For the treatment of adults and children with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Humalog is also indicated for the initial stabilisation of diabetes mellitus.

    For the treatment of patients with diabetes mellitus who require insulin for the maintenance of normal glucose homeostasis. Liprolog is also indicated for the initial stabilization of diabetes mellitus. Liprolog is a short acting insulin and may be used in conjunction with a longer acting human insulin. Liprolog is indicated for preprandial administration.

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Insulin is a natural hormone produced by beta cells of the pancreas. In non-diabetic individuals, a basal level of insulin is supplemented with insulin spikes following meals. Increased insulin secretion following meals is responsible for the metabolic changes that occur as the body transitions from a postabsorptive to absorptive state. Insulin promotes cellular uptake of glucose, particularly in muscle and adipose tissues, promotes energy storage via glycogenesis, opposes catabolism of energy stores, increases DNA replication and protein synthesis by stimulating amino acid uptake by liver, muscle and adipose tissue, and modifies the activity of numerous enzymes involved in glycogen synthesis and glycolysis. Insulin also promotes growth and is required for the actions of growth hormone (e.g. protein synthesis, cell division, DNA synthesis). Insulin lispro is a rapid-acting insulin analogue used to mimic postprandial insulin spikes in diabetic individuals. The onset of action of insulin lispro is 10-15 minutes. Its activity peaks 60 minutes following subcutaneous injection and its duration of action is 4-5 hours. Compared to regular human insulin, insulin lispro has a more rapid onset of action and a shorter duration of action. Insulin lispro is also shown to be equipotent to human insulin on a molar basis.

    5.2 MeSH Pharmacological Classification

    Hypoglycemic Agents

    Substances which lower blood glucose levels. (See all compounds classified as Hypoglycemic Agents.)

    5.3 FDA Pharmacological Classification
    5.3.1 Pharmacological Classes
    Insulin [Chemical/Ingredient]; Insulin Analog [EPC]
    5.4 ATC Code

    A10AB04

    A10AB04

    A10AB04, A10AD04

    A10AB04, A10AD04

    A10AB04

    A - Alimentary tract and metabolism

    A10 - Drugs used in diabetes

    A10A - Insulins and analogues

    A10AB - Insulins and analogues for injection, fast-acting

    A10AB04 - Insulin lispro

    A - Alimentary tract and metabolism

    A10 - Drugs used in diabetes

    A10A - Insulins and analogues

    A10AC - Insulins and analogues for injection, intermediate-acting

    A10AC04 - Insulin lispro

    A - Alimentary tract and metabolism

    A10 - Drugs used in diabetes

    A10A - Insulins and analogues

    A10AD - Insulins and analogues for injection, intermediate- or long-acting combined with fast-acting

    A10AD04 - Insulin lispro

    5.5 Absorption, Distribution and Excretion

    Absorption

    Insulin lispro is rapidly absorbed following subcutaneous administration. It is also absorbed more quickly than regular human insulin. Peak serum levels occur 30-90 minutes after injection in healthy subjects. Absorption also differs depending on the site of injection. After insulin lispro was administered in the abdomen, serum drug levels were higher and the duration of action was slightly shorter than after deltoid or thigh administration. The absolute bioavailability after subcutaneous injection ranges from 55% to 77% with doses between 0.1 to 0.2 unit/kg, inclusive. The mean observed area under the serum insulin concentration-time curve from time zero to infinity was 2360 pmol hr/L and 2390 pmol hr/L for HUMALOG U-200 and HUMALOG U-100, respectively. The corresponding mean peak serum insulin concentration was 795 pmol/L and 909 pmol/L for HUMALOG U-200 and HUMALOG U-100, respectively. The median time to maximum concentration was 1.0 hour for both formulations.

    Volume of Distribution

    When administered intravenously as bolus injections of 0.1 and 0.2 U/kg dose in two separate groups of healthy subjects, the mean volume of distribution of insulin lispro appeared to decrease with increase in dose (1.55 and 0.72 L/kg, respectively).

    Clearance

    Clearance is dose dependent. When a dose of 0.1 unit/kg and 0.2 unit/kg were administered intravenously, the mean clearance was 21.0 mL/min/kg and 9.6 mL/min/kg respectively.

    5.6 Metabolism/Metabolites

    Insulin is predominantly cleared by metabolic degradation via a receptor-mediated process.

    5.7 Biological Half-Life

    After subcutaneous administration of insulin lispro, the t1/2 is shorter than that of regular human insulin (1 versus 1.5 hours, respectively).

    5.8 Mechanism of Action

    Insulin lispro binds to the insulin receptor (IR), a heterotetrameric protein consisting of two extracellular alpha units and two transmembrane beta units. The binding of insulin to the alpha subunit of IR stimulates the tyrosine kinase activity intrinsic to the beta subunit of the receptor. The bound receptor autophosphorylates and phosphorylates numerous intracellular substrates such as insulin receptor substrates (IRS) proteins, Cbl, APS, Shc and Gab 1. Activation of these proteins leads to the activation of downstream signaling molecules including PI3 kinase and Akt. Akt regulates the activity of glucose transporter 4 (GLUT4) and protein kinase C (PKC), both of which play critical roles in metabolism and catabolism. In humans, insulin is stored in the form of hexamers; however, only insulin monomers are able to interact with IR. Reversal of the proline and lysine residues at positions B28 and B29 of native insulin eliminates hydrophobic interactions and weakens some of the hydrogen bonds that contribute to the stability of the insulin dimers that comprise insulin hexamers. Hexamers of insulin lispro are produced in the presence of zinc and m-cresol. These weakly associated hexamers quickly dissociate upon subcutaneous injection and are absorbed as monomers through vascular endothelial cells. These properties give insulin lispro its fast-acting properties.

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    Biocon

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    Novo Nordisk

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    Novo Nordisk

    Denmark

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5527

    Submission : 1984-09-14

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    04

    Novo Nordisk

    Denmark

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Novo Nordisk

    Denmark

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5533

    Submission : 1984-09-14

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    05

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 17123

    Submission : 2004-01-27

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    06

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 27702

    Submission : 2013-11-28

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    07

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Biocon

    India

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF Inactive-api
    ✖

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 32125

    Submission : 2017-12-01

    Status : Inactive

    Type : II

     CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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    Virtual Booth

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    08

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF CEP/COS JDMF arrow-down
    ✖

    Registration Number : 303MF10175

    Registrant's Address : 65th Infantry Road, Km. 12.6, Carolina, Puerto Rico 00985

    Initial Date of Registration : 2021-12-09

    Latest Date of Registration :

    EU-WC NDC KDMF VMF Others AUDIT
    blank

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    Virtual Booth

    Digital Content

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    Corporate PDF

    09

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF CEP/COS JDMF arrow-down
    ✖

    Registration Number : 217MF10534

    Registrant's Address : Lilly Corporate Center, Indianapolis, Indiana 46285, USA

    Initial Date of Registration : 2005-09-09

    Latest Date of Registration :

    EU-WC NDC KDMF VMF Others AUDIT
    blank

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    Virtual Booth

    Digital Content

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    10

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    World Dairy Expo
    Not Confirmed
    arrow

    Eli Lilly

    U.S.A

    USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

    arrow
    World Dairy Expo
    Not Confirmed
    USDMF CEP/COS JDMF arrow-down
    ✖

    Registration Number : 219MF10053

    Registrant's Address : 65th Infantry Road, Km. 12.6, Carolina, Puerto Rico 00985

    Initial Date of Registration : 2007-03-05

    Latest Date of Registration :

    EU-WC NDC KDMF VMF Others AUDIT
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    Only 10 entries up to this point, click to access all click full view read-more
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    USDMF

    read-more
    read-moreread-more

    01

    Sanofi Aventis Deutschland Gmbh

    France
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    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Contact Supplier Contact Supplier
    Flag France
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 4846

    Submission : 1983-03-11

    Status : Inactive

    Type : II

    Sanofi Company Banner

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    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    World Dairy Expo
    Not Confirmed

    02

    Biocon Biologics India Ltd

    India
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 23892

    Submission : 2010-06-07

    Status : Active

    Type : II

    blank

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    Product Web Link

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    Digital Content

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    03

    World Dairy Expo
    Not Confirmed

    03

    Biocon Biologics India Ltd

    India
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 17123

    Submission : 2004-01-27

    Status : Inactive

    Type : II

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    Biocon Sdn Bhd

    India

    USDMF

    arrow
    World Dairy Expo
    Not Confirmed

    04

    Biocon Sdn Bhd

    India
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 32125

    Submission : 2017-12-01

    Status : Inactive

    Type : II

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

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    Corporate PDF

    05

    Biocon Ltd

    India

    USDMF

    arrow
    World Dairy Expo
    Not Confirmed

    05

    Biocon Ltd

    India
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 27702

    Submission : 2013-11-28

    Status : Inactive

    Type : II

    blank

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    Product Web Link

    Virtual Booth

    Digital Content

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    Corporate PDF

    06

    Novo Nordisk As

    Denmark

    USDMF

    arrow
    World Dairy Expo
    Not Confirmed

    06

    Novo Nordisk As

    Denmark
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5533

    Submission : 1984-09-14

    Status : Inactive

    Type : II

    blank

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    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    07

    Novo Nordisk As

    Denmark

    USDMF

    arrow
    World Dairy Expo
    Not Confirmed

    07

    Novo Nordisk As

    Denmark
    arrow
    World Dairy Expo
    Not Confirmed

    GDUFA

    DMF Review : N/A

    Rev. Date :

    Pay. Date :

    DMF Number : 5527

    Submission : 1984-09-14

    Status : Inactive

    Type : II

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

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    JDMF

    read-more
    read-moreread-more

    01

    Lilly del Caribe, Inc.

    U.S.A
    World Dairy Expo
    Not Confirmed
    arrow

    Lilly del Caribe, Inc.

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    Post an Enquiry Post an Enquiry
    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin lispro (genetical recombination)

    Registration Number : 303MF10175

    Registrant's Address : 65th Infantry Road, Km. 12.6, Carolina, Puerto Rico 00985

    Initial Date of Registration : 2021-12-09

    Latest Date of Registration : 2021-12-09

    blank

    Portfolio PDF

    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    02

    Eli Lilly and Company

    U.S.A
    World Dairy Expo
    Not Confirmed
    arrow

    Eli Lilly and Company

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    Post an Enquiry Post an Enquiry
    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin lispro (genetical recombination)

    Registration Number : 226MF10225

    Registrant's Address : Lilly Corporate Center, Indianapolis, Indiana 46285, USA

    Initial Date of Registration : 2014-12-08

    Latest Date of Registration : 2017-12-25

    blank

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    Product Web Link

    Virtual Booth

    Digital Content

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    03

    Eli Lilly and Company

    U.S.A
    World Dairy Expo
    Not Confirmed
    arrow

    Eli Lilly and Company

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    Post an Enquiry Post an Enquiry
    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin lispro (genetical recombination)

    Registration Number : 217MF10534

    Registrant's Address : Lilly Corporate Center, Indianapolis, Indiana 46285, USA

    Initial Date of Registration : 2005-09-09

    Latest Date of Registration : 2017-12-25

    blank

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    Product Web Link

    Virtual Booth

    Digital Content

    Website

    Corporate PDF

    04

    Lilly del Caribe, Inc.

    U.S.A
    World Dairy Expo
    Not Confirmed
    arrow

    Lilly del Caribe, Inc.

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    Post an Enquiry Post an Enquiry
    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin lispro (genetical recombination)

    Registration Number : 229MF10064

    Registrant's Address : 65th Infantry Road, Km. 12.6, Carolina, Puerto Rico 00985

    Initial Date of Registration : 2017-03-13

    Latest Date of Registration : 2017-12-25

    blank

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    Virtual Booth

    Digital Content

    Website

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    05

    Lilly del Caribe, Inc.

    U.S.A
    World Dairy Expo
    Not Confirmed
    arrow

    Lilly del Caribe, Inc.

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
    Post an Enquiry Post an Enquiry
    Flag U.S.A
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin lispro (genetical recombination)

    Registration Number : 219MF10053

    Registrant's Address : 65th Infantry Road, Km. 12.6, Carolina, Puerto Rico 00985

    Initial Date of Registration : 2007-03-05

    Latest Date of Registration : 2017-12-25

    blank

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    Listed Suppliers

    read-more
    read-more

    01

    Wanbang Biopharmaceuticals

    China
    World Dairy Expo
    Not Confirmed
    arrow

    Wanbang Biopharmaceuticals

    China
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
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    Flag China
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Insulin Lispro

    About the Company : Wanbang Biopharmaceuticals is a leading anti-diabetic pharmaceutical company in China and a core member of Fosun Group (SH600196; HK02196). Wanbang Biopharma has been focusing at t...

    Wanbang Biopharmaceuticals is a leading anti-diabetic pharmaceutical company in China and a core member of Fosun Group (SH600196; HK02196). Wanbang Biopharma has been focusing at the development, manufacture and sale of pharmaceuticals to address the unmet medical needs in the area of diabetic disease since its establishment in 1981.As the pioneer insulin producer in China, Wanbang has been developed into the largest anti-diabetic pharmaceutical provider of China with a comprehensive product portfolio that covers a wide range of anti-diabetic drugs, serving for more than eight million diabetic patients.
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    Drugs in Development

    read-more
    read-more
    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patients With Type 1 Diabetes

    Details:

    Insulin Lispro is a Peptide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 1.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Peptide, Unconjugated

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable April 04, 2019

    Sanofi Company Banner

    01

    Sanofi

    France
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patient...

    Details : Insulin Lispro is a Peptide drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 1.

    Product Name : Undisclosed

    Product Type : Peptide, Unconjugated

    Upfront Cash : Inapplicable

    April 04, 2019

    Sanofi Company Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

    Virtual Booth

    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)

    Details:

    Insulin Glargine is a Peptide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 1.


    Lead Product(s): Insulin Glargine,Insulin Lispro,Insulin aspart,Insulin Glulisine

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IVProduct Type: Peptide, Unconjugated

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable August 24, 2017

    Sanofi Company Banner

    02

    Sanofi

    France
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : Insulin Glargine,Insulin Lispro,Insulin aspart,Insulin Glulisine

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase IV

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients ...

    Details : Insulin Glargine is a Peptide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 1.

    Product Name : Undisclosed

    Product Type : Peptide, Unconjugated

    Upfront Cash : Inapplicable

    August 24, 2017

    Sanofi Company Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

    Virtual Booth

    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Assessment of the Safety of SAR342434 and Humalog® When Administered as Continuous Subcutaneous Insulin Infusion

    Details:

    SAR342434 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 1.


    Lead Product(s): SAR342434,Insulin Lispro

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IProduct Type: Undisclosed

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable November 11, 2015

    Sanofi Company Banner

    03

    Sanofi

    France
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : SAR342434,Insulin Lispro

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase I

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Assessment of the Safety of SAR342434 and Humalog® When Administered as Continuous Subcutaneous...

    Details : SAR342434 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Diabetes Mellitus, Type 1.

    Product Name : Undisclosed

    Product Type : Undisclosed

    Upfront Cash : Inapplicable

    November 11, 2015

    Sanofi Company Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

    Virtual Booth

    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Efficacy and Safety of Insuman Basal/Comb/Rapid in Patients With Type 2 Diabetes

    Details:

    Human Insulin is a Protein drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 2.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IVProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable June 28, 2012

    Sanofi Company Banner

    04

    Sanofi

    France
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase IV

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Efficacy and Safety of Insuman Basal/Comb/Rapid in Patients With Type 2 Diabetes

    Details : Human Insulin is a Protein drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 2.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    June 28, 2012

    Sanofi Company Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

    Virtual Booth

    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Assessment of Efficacy and Safety of Insuman Comb 25 Versus Novolin® 30R Twice Daily Over 24 Weeks in Type 2 Diabetes Patients With Insulin Therapy

    Details:

    Human Insulin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetes Mellitus, Type 2.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IIIProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable May 13, 2011

    Sanofi Company Banner

    05

    Sanofi

    France
    arrow
    CPhI WW Frankfurt
    Attending
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase III

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Assessment of Efficacy and Safety of Insuman Comb 25 Versus Novolin® 30R Twice Daily Over 24 We...

    Details : Human Insulin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetes Mellitus, Type 2.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    May 13, 2011

    Sanofi Company Banner

    Stock Recap
    #PipelineProspector

    Data Compilation
    #PharmaFlow

    Virtual Booth

    • Development Update
    • fda
    • EDQM
    • WHO-GMP
    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Benefit/Risk Evaluation of Insuman Implantable Versus Insuplant Using Medtronic MiniMed Implantable Pump System in Patients With Type 1 Diabetes

    Details:

    Human Insulin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetes Mellitus, Type 1.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IIIProduct Type: Protein

    Sponsor: Undisclosed

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable September 03, 2010

    Sanofi Company Banner

    06

    Sanofi

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase III

    Partner/Sponsor/Collaborator : Undisclosed

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Benefit/Risk Evaluation of Insuman Implantable Versus Insuplant Using Medtronic MiniMed Implantabl...

    Details : Human Insulin is a Protein drug candidate, which is currently being evaluated in phase III clinical studies for the treatment of Diabetes Mellitus, Type 1.

    Product Name : Undisclosed

    Product Type : Protein

    Upfront Cash : Inapplicable

    September 03, 2010

    Sanofi Company Banner

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    Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?

    Details:

    Haloperidol is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of unspecified medical condition.


    Lead Product(s): Haloperidol,Insulin Lispro,Sodium Chloride

    Therapeutic Area: Undisclosed Brand Name: Undisclosed

    Study Phase: Phase IVProduct Type: Miscellaneous

    Sponsor: Physician Services Incorporated

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable August 07, 2025

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    07

    Centre for Addiction and Mental Health

    Country
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    World Dairy Expo
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    Centre for Addiction and Mental Health

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    Lead Product(s) : Haloperidol,Insulin Lispro,Sodium Chloride

    Therapeutic Area : Undisclosed

    Highest Development Status : Phase IV

    Partner/Sponsor/Collaborator : Physician Services Incorporated

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?

    Details : Haloperidol is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of unspecified medical condition.

    Product Name : Undisclosed

    Product Type : Miscellaneous

    Upfront Cash : Inapplicable

    August 07, 2025

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    Lupin Acquires Huminsulin from Lilly, Enhance Diabetes Portfolio

    Details:

    Through the acquisition, Lupin will enhance its portfolio and gain the right to commercialize Humulin N (human insulin) in India. It is indicated for the treatment of diabetes mellitus.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Humulin N

    Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

    Sponsor: Lupin Ltd

    Deal Size: Undisclosed Upfront Cash: Undisclosed

    Deal Type: Acquisition December 30, 2024

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    08

    Eli Lilly

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    U.S.A
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    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Lupin Ltd

    Deal Size : Undisclosed

    Deal Type : Acquisition

    DEALS_DEV arrow-down

    Lupin Acquires Huminsulin from Lilly, Enhance Diabetes Portfolio

    Details : Through the acquisition, Lupin will enhance its portfolio and gain the right to commercialize Humulin N (human insulin) in India. It is indicated for the treatment of diabetes mellitus.

    Product Name : Humulin N

    Product Type : Peptide, Unconjugated

    Upfront Cash : Undisclosed

    December 30, 2024

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    Lilly, EVA Pharma Announce Regulatory Approval for Locally Manufactured Insulin

    Details:

    Humalog (insulin) is a peptide based drug, works by showing agonistic action for GLP-1R, mainly indicated for the treatment of patients with type 1 and 2 diabetes.


    Lead Product(s): Insulin Lispro,Inapplicable

    Therapeutic Area: Endocrinology Brand Name: Humalog

    Study Phase: Approved FDFProduct Type: Peptide, Unconjugated

    Sponsor: Eli Lilly

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable December 17, 2024

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    09

    Eva Pharma

    Egypt
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    World Dairy Expo
    Not Confirmed

    Eva Pharma

    Egypt
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    Lead Product(s) : Insulin Lispro,Inapplicable

    Therapeutic Area : Endocrinology

    Highest Development Status : Approved FDF

    Partner/Sponsor/Collaborator : Eli Lilly

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Lilly, EVA Pharma Announce Regulatory Approval for Locally Manufactured Insulin

    Details : Humalog (insulin) is a peptide based drug, works by showing agonistic action for GLP-1R, mainly indicated for the treatment of patients with type 1 and 2 diabetes.

    Product Name : Humalog

    Product Type : Peptide, Unconjugated

    Upfront Cash : Inapplicable

    December 17, 2024

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    A Study of LY900014 in Adult Participants With Type 2 Diabetes Mellitus in India

    Details:

    Insulin Lispro is a Peptide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 2.


    Lead Product(s): Insulin Lispro,Insulin Glargine

    Therapeutic Area: Endocrinology Brand Name: Undisclosed

    Study Phase: Phase IVProduct Type: Peptide, Unconjugated

    Sponsor: Cipla

    Deal Size: Inapplicable Upfront Cash: Inapplicable

    Deal Type: Inapplicable April 17, 2024

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    10

    Eli Lilly

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    U.S.A
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    World Dairy Expo
    Not Confirmed
    • fda
    • EDQM
    • WHO-GMP
    Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

    Lead Product(s) : Insulin Lispro,Insulin Glargine

    Therapeutic Area : Endocrinology

    Highest Development Status : Phase IV

    Partner/Sponsor/Collaborator : Cipla

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    A Study of LY900014 in Adult Participants With Type 2 Diabetes Mellitus in India

    Details : Insulin Lispro is a Peptide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Diabetes Mellitus, Type 2.

    Product Name : Undisclosed

    Product Type : Peptide, Unconjugated

    Upfront Cash : Inapplicable

    April 17, 2024

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    01

    SANOFI-AVENTIS US

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
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    RLD :

    TE Code :

    INSULIN LISPRO

    Brand Name : ADMELOG

    Dosage Form : SOLUTION;INTRAVENOUS, SUBCUTANEOUS

    Dosage Strength : 1000 UNITS/10ML (100 UNITS/ML)

    Approval Date :

    Application Number : 209196

    RX/OTC/DISCN :

    RLD :

    TE Code :

    Sanofi Company Banner

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    02

    SANOFI-AVENTIS US

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Digital Content Digital Content

    RLD :

    TE Code :

    INSULIN LISPRO

    Brand Name : ADMELOG SOLOSTAR

    Dosage Form : SOLUTION;INTRAVENOUS, SUBCUTANEOUS

    Dosage Strength : 300 UNITS/3ML (100 UNITS/ML)

    Approval Date :

    Application Number : 209196

    RX/OTC/DISCN :

    RLD :

    TE Code :

    Sanofi Company Banner

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    03

    SANOFI-AVENTIS US

    France
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    Attending
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    RLD :

    TE Code :

    INSULIN LISPRO

    Brand Name : ADMELOG

    Dosage Form : SOLUTION;INTRAVENOUS, SUBCUTANEOUS

    Dosage Strength : 300 UNITS/3ML (100 UNITS/ML)

    Approval Date :

    Application Number : 209196

    RX/OTC/DISCN :

    RLD :

    TE Code :

    Sanofi Company Banner

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    Europe

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    01

    Sanofi-aventis Deutschland GmbH

    France
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    Attending
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Regulatory Info :

    Registration Country : Norway

    Insulin Lispro

    Brand Name : Insuman Basal

    Dosage Form : Injection fluid, suspension

    Dosage Strength : 100 IE/ml

    Packaging : Hood glass

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

    Sanofi Company Banner

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    02

    Sanofi-aventis Deutschland GmbH

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Regulatory Info :

    Registration Country : Norway

    Insulin Lispro

    Brand Name : Insuman Comb 25

    Dosage Form : Injection fluid, suspension

    Dosage Strength : 100 IE/ml

    Packaging : Sylinderampulle

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

    Sanofi Company Banner

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    03

    Sanofi-aventis Deutschland GmbH

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info :

    Registration Country : Norway

    Insulin Lispro

    Brand Name : Insuman Rapid

    Dosage Form : Injection fluid, resolution

    Dosage Strength : 100 IE/ml

    Packaging : Sylinderampulle

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Norway

    Sanofi Company Banner

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    04

    Sanofi-Aventis Deutschland Gmbh

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Digital Content Digital Content

    Regulatory Info : Approved

    Registration Country : Sweden

    Human Insulin (Soluble)

    Brand Name : Insuman Infusat

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 11/11/1998

    Application Number : 19970221000111

    Regulatory Info : Approved

    Registration Country : Sweden

    Sanofi Company Banner

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    05

    Sanofi-Aventis Deutschland Gmbh

    France
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    Attending
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Digital Content Digital Content

    Regulatory Info : Approved

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insuman Comb 25 Solostar

    Dosage Form : Suspension For Injection

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 31/10/2008

    Application Number : 20081016000103

    Regulatory Info : Approved

    Registration Country : Sweden

    Sanofi Company Banner

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    06

    Sanofi-Aventis Deutschland Gmbh

    France
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    Attending
    • fda
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    • WHO-GMP

    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Approved

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insuman Comb 50

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 11/11/1998

    Application Number : 19970221000098

    Regulatory Info : Approved

    Registration Country : Sweden

    Sanofi Company Banner

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    Digital Content

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    07

    Sanofi-Aventis Deutschland Gmbh

    France
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    CPhI WW Frankfurt
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Deregistered

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insulin Human Winthrop Comb 15

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 17/01/2007

    Application Number : 20060824000116

    Regulatory Info : Deregistered

    Registration Country : Sweden

    Sanofi Company Banner

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    08

    Sanofi-Aventis Deutschland Gmbh

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
    Virtual Booth Virtual Booth
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    Regulatory Info : Deregistered

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insulin Human Winthrop Comb 25

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 17/01/2007

    Application Number : 20060824000147

    Regulatory Info : Deregistered

    Registration Country : Sweden

    Sanofi Company Banner

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    Digital Content

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    09

    Sanofi-Aventis Deutschland Gmbh

    France
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    Attending
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
    Virtual Booth Virtual Booth
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    Regulatory Info : Deregistered

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insulin Human Winthrop Comb 25

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 17/01/2007

    Application Number : 20060824000154

    Regulatory Info : Deregistered

    Registration Country : Sweden

    Sanofi Company Banner

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    10

    Sanofi-Aventis Deutschland Gmbh

    France
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    Attending
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Flag France
    Virtual Booth Virtual Booth
    Digital Content Digital Content

    Regulatory Info : Deregistered

    Registration Country : Sweden

    Human Insulin (Soluble); Human Insulin Isophane (NPH)

    Brand Name : Insulin Human Winthrop Comb 30

    Dosage Form : Injectable Solution

    Dosage Strength : 100IU/ml

    Packaging :

    Approval Date : 19/02/2009

    Application Number : 20080112000109

    Regulatory Info : Deregistered

    Registration Country : Sweden

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    Canada

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    SANOFI-AVENTIS CANADA INC

    France
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : ADMELOG

    Dosage Form : SOLUTION

    Dosage Strength : 100UNIT/ML

    Packaging : 3ML CARTRIDGE

    Approval Date :

    Application Number : 2469898

    Regulatory Info : Schedule D

    Registration Country : Canada

    Sanofi Company Banner

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    02

    SANOFI-AVENTIS CANADA INC

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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : ADMELOG SOLOSTAR

    Dosage Form : SOLUTION

    Dosage Strength : 100UNIT/ML

    Packaging : 3ML PREFILLED PEN

    Approval Date :

    Application Number : 2469871

    Regulatory Info : Schedule D

    Registration Country : Canada

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    03

    SANOFI-AVENTIS CANADA INC

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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : ADMELOG

    Dosage Form : SOLUTION

    Dosage Strength : 100UNIT/ML

    Packaging : 10ML VIAL

    Approval Date :

    Application Number : 2469901

    Regulatory Info : Schedule D

    Registration Country : Canada

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    04

    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
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    ELI LILLY CANADA INC

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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : HUMALOG

    Dosage Form : SOLUTION

    Dosage Strength : 100UNIT/ML

    Packaging : 3/10ML

    Approval Date :

    Application Number : 2229704

    Regulatory Info : Schedule D

    Registration Country : Canada

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    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
    Not Confirmed
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    ELI LILLY CANADA INC

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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : HUMALOG (CARTRIDGE)

    Dosage Form : SOLUTION

    Dosage Strength : 100UNIT/ML

    Packaging : 1.5/3ML

    Approval Date :

    Application Number : 2229705

    Regulatory Info : Schedule D

    Registration Country : Canada

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    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
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    ELI LILLY CANADA INC

    U.S.A
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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO PROTAMINE SUSPENSION

    Brand Name : HUMALOG MIX 50 (CARTRIDGE)

    Dosage Form : SUSPENSION

    Dosage Strength : 50UNIT/ML

    Packaging : 3.0ML

    Approval Date :

    Application Number : 2240297

    Regulatory Info : Schedule D

    Registration Country : Canada

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    07

    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
    Not Confirmed
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    ELI LILLY CANADA INC

    U.S.A
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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : HUMALOG MIX 50 (CARTRIDGE)

    Dosage Form : SUSPENSION

    Dosage Strength : 50UNIT/ML

    Packaging : 3.0ML

    Approval Date :

    Application Number : 2240297

    Regulatory Info : Schedule D

    Registration Country : Canada

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    08

    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
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    U.S.A
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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO PROTAMINE SUSPENSION

    Brand Name : HUMALOG MIX 25 (KWIKPEN)

    Dosage Form : SUSPENSION

    Dosage Strength : 75UNIT/ML

    Packaging :

    Approval Date :

    Application Number : 2403420

    Regulatory Info : Schedule D

    Registration Country : Canada

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    09

    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
    Not Confirmed
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    ELI LILLY CANADA INC

    U.S.A
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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO PROTAMINE SUSPENSION

    Brand Name : HUMALOG MIX 50 (KWIKPEN)

    Dosage Form : SUSPENSION

    Dosage Strength : 50UNIT/ML

    Packaging : 3ML/PEN

    Approval Date :

    Application Number : 2403439

    Regulatory Info : Schedule D

    Registration Country : Canada

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    10

    ELI LILLY CANADA INC

    U.S.A
    World Dairy Expo
    Not Confirmed
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    ELI LILLY CANADA INC

    U.S.A
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    Regulatory Info : Schedule D

    Registration Country : Canada

    INSULIN LISPRO

    Brand Name : HUMALOG 200 UNITS/ML KWIKPEN

    Dosage Form : SOLUTION

    Dosage Strength : 200UNIT/ML

    Packaging : 3ML

    Approval Date :

    Application Number : 2439611

    Regulatory Info : Schedule D

    Registration Country : Canada

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    Australia

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    01

    Eli Lilly Australia Pty Ltd

    U.S.A
    World Dairy Expo
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    Eli Lilly Australia Pty Ltd

    U.S.A
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    Regulatory Info :

    Registration Country : Australia

    Insulin lispro

    Brand Name : Humalog U200 Kwikpen

    Dosage Form :

    Dosage Strength :

    Packaging : 1

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    02

    Eli Lilly Australia Pty Ltd

    U.S.A
    World Dairy Expo
    Not Confirmed
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    Eli Lilly Australia Pty Ltd

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    Regulatory Info :

    Registration Country : Australia

    Insulin lispro

    Brand Name : Humalog KwikPen

    Dosage Form :

    Dosage Strength :

    Packaging : 1

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    03

    Eli Lilly Australia Pty Ltd

    U.S.A
    World Dairy Expo
    Not Confirmed
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    Eli Lilly Australia Pty Ltd

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    Regulatory Info :

    Registration Country : Australia

    Insulin lispro

    Brand Name : Humalog

    Dosage Form :

    Dosage Strength :

    Packaging : 1

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    04

    Eli Lilly Australia Pty Ltd

    U.S.A
    World Dairy Expo
    Not Confirmed
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    Eli Lilly Australia Pty Ltd

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    Regulatory Info :

    Registration Country : Australia

    Insulin lispro

    Brand Name : Humalog

    Dosage Form :

    Dosage Strength :

    Packaging : 1

    Approval Date :

    Application Number :

    Regulatory Info :

    Registration Country : Australia

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    01

    Brand Name : Admelog

    France
    arrow
    World Dairy Expo
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    Brand Name : Admelog

    France
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    Company : Sanofi-Aventis

    Insulin Lispro

    Drug Cost (USD) : 1,393,724

    Year : 2023

    Prescribers : 4971

    Prescriptions : 10933

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    02

    Brand Name : Admelog Solostar

    France
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Admelog Solostar

    France
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    World Dairy Expo
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    Company : Sanofi-Aventis

    Insulin Lispro

    Drug Cost (USD) : 4,074,927

    Year : 2023

    Prescribers : 11113

    Prescriptions : 24807

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    03

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
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    Company : Eli Lilly & Co.

    Insulin Lispro

    Drug Cost (USD) : 458,058,582

    Year : 2023

    Prescribers : 156031

    Prescriptions : 572082

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    04

    Brand Name : Humalog Junior Kwikpen

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Junior Kwikpen

    U.S.A
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    World Dairy Expo
    Not Confirmed
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    Company : Eli Lilly & Co.

    Insulin Lispro

    Drug Cost (USD) : 9,905,950

    Year : 2023

    Prescribers : 5648

    Prescriptions : 15111

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    05

    Brand Name : Humalog Kwikpen U-100

    U.S.A
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    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Kwikpen U-100

    U.S.A
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    World Dairy Expo
    Not Confirmed
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    Company : Eli Lilly & Co.

    Insulin Lispro

    Drug Cost (USD) : 1,208,385,334

    Year : 2023

    Prescribers : 418431

    Prescriptions : 1363952

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    06

    Brand Name : Humalog Kwikpen U-200

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Kwikpen U-200

    U.S.A
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    World Dairy Expo
    Not Confirmed
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    Company : Eli Lilly & Co.

    Insulin Lispro

    Drug Cost (USD) : 224,440,404

    Year : 2023

    Prescribers : 40611

    Prescriptions : 143978

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    07

    Brand Name : Humalog Mix 50-50

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Mix 50-50

    U.S.A
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    World Dairy Expo
    Not Confirmed
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    Company : Eli Lilly & Co.

    Insulin Lispro Protamin/Lispro

    Drug Cost (USD) : 6,085,553

    Year : 2023

    Prescribers : 1297

    Prescriptions : 6483

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    08

    Brand Name : Humalog Mix 50-50 Kwikpen

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Mix 50-50 Kwikpen

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed
    • fda
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    Company : Eli Lilly & Co.

    Insulin Lispro Protamin/Lispro

    Drug Cost (USD) : 20,294,452

    Year : 2023

    Prescribers : 3890

    Prescriptions : 16268

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    09

    Brand Name : Humalog Mix 75-25

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Mix 75-25

    U.S.A
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    World Dairy Expo
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    Company : Eli Lilly & Co.

    Insulin Lispro Protamin/Lispro

    Drug Cost (USD) : 59,917,382

    Year : 2023

    Prescribers : 12749

    Prescriptions : 62177

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    10

    Brand Name : Humalog Mix 75-25 Kwikpen

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog Mix 75-25 Kwikpen

    U.S.A
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    World Dairy Expo
    Not Confirmed
    • fda
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    Company : Eli Lilly & Co.

    Insulin Lispro Protamin/Lispro

    Drug Cost (USD) : 213,875,690

    Year : 2023

    Prescribers : 40527

    Prescriptions : 171187

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    Annual Reports

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    01

    Brand Name : Admelog/Insulin Lispro

    France
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    Not Confirmed
    Contact Supplier Contact Supplier
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    Virtual Booth Virtual Booth
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    • fda
    • EDQM
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    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Sanofi

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2019 Revenue in Millions : 273

    2018 Revenue in Millions : 101

    Growth (%) : 169

    Sanofi Company Banner

    Portfolio PDF

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    02

    Brand Name : Admelog/Insulin Lispro

    France
    arrow
    World Dairy Expo
    Not Confirmed
    Contact Supplier Contact Supplier
    Flag France
    Virtual Booth Virtual Booth
    Digital Content Digital Content
    • fda
    • EDQM
    • WHO-GMP

    Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

    Sanofi

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2018 Revenue in Millions : 105

    2017 Revenue in Millions : 0

    Growth (%) : NA

    Sanofi Company Banner

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    03

    Brand Name : Humalog

    Insulin Lispro

    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2020 Revenue in Millions : 2,626

    2019 Revenue in Millions : 2,821

    Growth (%) : -7

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    04

    Brand Name : Humalog

    Insulin Lispro

    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2021 Revenue in Millions : 2,453

    2020 Revenue in Millions : 2,626

    Growth (%) : -7

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    05

    Brand Name : Humalog

    Insulin Lispro

    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2022 Revenue in Millions : 2,061

    2021 Revenue in Millions : 2,453

    Growth (%) : -16

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    06

    Brand Name : Humalog

    Insulin Lispro

    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2023 Revenue in Millions : 1,663

    2022 Revenue in Millions : 2,061

    Growth (%) : -19

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    07

    Brand Name : Humalog

    Insulin Lispro

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    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
    World Dairy Expo
    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2024 Revenue in Millions : 2,325

    2023 Revenue in Millions : 1,663

    Growth (%) : 40

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    08

    Brand Name : Humalog

    Insulin Lispro

    arrow
    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
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    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2015 Revenue in Millions : 2,785

    2014 Revenue in Millions : 2,842

    Growth (%) : 2%

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    09

    Brand Name : Humalog

    Insulin Lispro

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    Brand Name : Humalog

    U.S.A
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    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2014 Revenue in Millions : 6.70%

    2013 Revenue in Millions :

    Growth (%) :

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    10

    Brand Name : Humalog

    Insulin Lispro

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    World Dairy Expo
    Not Confirmed

    Brand Name : Humalog

    U.S.A
    arrow
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    Not Confirmed

    Eli Lilly

    Insulin Lispro

    Main Therapeutic Indication : Diabetes

    Currency : USD

    2016 Revenue in Millions : 2,769

    2015 Revenue in Millions : 2,842

    Growth (%) : -3

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    ABOUT THIS PAGE

    Looking for 133107-64-9 / Insulin Lispro API manufacturers, exporters & distributors?

    Insulin Lispro manufacturers, exporters & distributors 1

    41

    PharmaCompass offers a list of Insulin Lispro API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Insulin Lispro manufacturer or Insulin Lispro supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Insulin Lispro manufacturer or Insulin Lispro supplier.

    PharmaCompass also assists you with knowing the Insulin Lispro API Price utilized in the formulation of products. Insulin Lispro API Price is not always fixed or binding as the Insulin Lispro Price is obtained through a variety of data sources. The Insulin Lispro Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Insulin Lispro

    Synonyms

    133107-64-9, Insulin lispro (5.97 mg), Insulin-lispro, Dtxsid90157956

    Cas Number

    133107-64-9

    About Insulin Lispro

    Insulin that has been modified so that the B-chain contains a LYSINE at position 28 instead of a PROLINE and a PROLINE at position 29 instead of a LYSINE. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.

    Insulin Lispro Manufacturers

    A Insulin Lispro manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Insulin Lispro, including repackagers and relabelers. The FDA regulates Insulin Lispro manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Insulin Lispro API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Insulin Lispro manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Insulin Lispro Suppliers

    A Insulin Lispro supplier is an individual or a company that provides Insulin Lispro active pharmaceutical ingredient (API) or Insulin Lispro finished formulations upon request. The Insulin Lispro suppliers may include Insulin Lispro API manufacturers, exporters, distributors and traders.

    click here to find a list of Insulin Lispro suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Insulin Lispro USDMF

    A Insulin Lispro DMF (Drug Master File) is a document detailing the whole manufacturing process of Insulin Lispro active pharmaceutical ingredient (API) in detail. Different forms of Insulin Lispro DMFs exist exist since differing nations have different regulations, such as Insulin Lispro USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Insulin Lispro DMF submitted to regulatory agencies in the US is known as a USDMF. Insulin Lispro USDMF includes data on Insulin Lispro's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Insulin Lispro USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Insulin Lispro suppliers with USDMF on PharmaCompass.

    Insulin Lispro JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Insulin Lispro Drug Master File in Japan (Insulin Lispro JDMF) empowers Insulin Lispro API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Insulin Lispro JDMF during the approval evaluation for pharmaceutical products. At the time of Insulin Lispro JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Insulin Lispro suppliers with JDMF on PharmaCompass.

    Insulin Lispro GMP

    Insulin Lispro Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Insulin Lispro GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Insulin Lispro GMP manufacturer or Insulin Lispro GMP API supplier for your needs.

    Insulin Lispro CoA

    A Insulin Lispro CoA (Certificate of Analysis) is a formal document that attests to Insulin Lispro's compliance with Insulin Lispro specifications and serves as a tool for batch-level quality control.

    Insulin Lispro CoA mostly includes findings from lab analyses of a specific batch. For each Insulin Lispro CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Insulin Lispro may be tested according to a variety of international standards, such as European Pharmacopoeia (Insulin Lispro EP), Insulin Lispro JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Insulin Lispro USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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