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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : SAR447971

                          Therapeutic Area : Dermatology

                          Study Phase : IND Enabling

                          Recipient : Kymera Therapeutics

                          Deal Size : $2,150.0 million

                          Deal Type : Collaboration

                          Details : Sanofi has informed Kymera that KT-485/SAR447971, an oral, highly potent and selective development candidate targeting IRAK4 has been selected to advance into clinical studies.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $150.0 million

                          June 25, 2025

                          Lead Product(s) : SAR447971

                          Therapeutic Area : Dermatology

                          Highest Development Status : IND Enabling

                          Recipient : Kymera Therapeutics

                          Deal Size : $2,150.0 million

                          Deal Type : Collaboration

                          Sanofi Company Banner

                          02

                          Lead Product(s) : mRNA Vaccine

                          Therapeutic Area : Dermatology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : MRNA Vaccine is a Vaccine drug candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Acne Vulgaris.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Inapplicable

                          June 10, 2025

                          Lead Product(s) : mRNA Vaccine

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          03

                          Lead Product(s) : ENV-294

                          Therapeutic Area : Dermatology

                          Study Phase : Phase I

                          Recipient : Enveda Bioscience

                          Deal Size : $150.0 million

                          Deal Type : Series C Financing

                          Details : The financing aims to advance the development of company's pipeline, which includes ENV-294, a first-in-class, oral small molecule, with JAK-inhibitor. It is being evaluated for Atopic Dermatitis.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 26, 2025

                          Lead Product(s) : ENV-294

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I

                          Recipient : Enveda Bioscience

                          Deal Size : $150.0 million

                          Deal Type : Series C Financing

                          Sanofi Company Banner

                          04

                          Lead Product(s) : Lunsekimig

                          Therapeutic Area : Dermatology

                          Study Phase : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          January 23, 2025

                          Lead Product(s) : Lunsekimig

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          05

                          Lead Product(s) : Fluorouracil

                          Therapeutic Area : Dermatology

                          Study Phase : Phase I/ Phase II

                          Recipient : Skin Laser & Surgery Specialists

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          December 02, 2024

                          Lead Product(s) : Fluorouracil

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Skin Laser & Surgery Specialists

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          06

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Dermatology

                          Study Phase : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          07

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Dermatology

                          Study Phase : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 14, 2024

                          Lead Product(s) : Dupilumab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase III

                          Sponsor : Regeneron Pharmaceuticals

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          08

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Dermatology

                          Study Phase : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 13, 2024

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          09

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Dermatology

                          Study Phase : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : KY1005 (amlitelimab) is a non-T cell depleting antibody blocking OX40-Ligand, potential first-in-class for moderate-to-severe atopic dermatitis.

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          November 03, 2024

                          Lead Product(s) : Amlitelimab

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          10

                          Lead Product(s) : ASN008

                          Therapeutic Area : Dermatology

                          Study Phase : Phase II

                          Recipient : Formation Bio

                          Deal Size : $372.0 million

                          Deal Type : Series D Financing

                          Details : The fund aims to advance the pipeline, which includes the company lead product ASN008, a sodium channel blocker. Currently, it is being evaluated for the treatment of atopic dermatitis.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          June 26, 2024

                          Lead Product(s) : ASN008

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase II

                          Recipient : Formation Bio

                          Deal Size : $372.0 million

                          Deal Type : Series D Financing

                          Sanofi Company Banner