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    Pharma Services Category of Piramal Pharma Solutions

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    HTL Biotechnology is the world leader in the responsible development and production of pharmaceutical-grade biopolymers.
    Polpharma is a Polish CDMO of APIs and a significant European API producer, delivering products to companies worldwide.
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    01 API Development (10)

    02 Antibody Drug Conjugate (1)

    03 BioAnalytical Services (1)

    04 Biologic Drugs (1)

    05 Capsule (1)

    06 Chiral Synthesis (1)

    07 Clinical Services (1)

    08 Clinical Supply (1)

    09 Contract Manufacturing (1)

    10 Cream / Lotion / Ointment (1)

    11 Fine Chemical / Intermediate (1)

    12 Formulation Development (13)

    13 GMP Manufacturing (1)

    14 High Potency APIs (HPAPIs) (1)

    15 Injectable / Parenteral (2)

    16 Liquid (1)

    17 Preformulation & Material Science (3)

    18 Process Development & Optimization (1)

    19 Protein / Peptide (1)

    20 Tablet (6)

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    Piramal Pharma Solutions

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    FORMULATION DEVELOPMENT FOR CLINICAL SUPPLY

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    Piramal offers clinical development services from Phase I to Phase III for various dosage forms, such as oral solids, liquids, creams, ointments and sterile injectables.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Clinical Supply
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    FORMULATION DEVELOPMENT OF TABLETS

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    Piramal offers pharmaceutical development services for oral solids, such as oral disintegrating tablets, sublingual tablets, press-coated tablets, bi-layered, delayed & modified-release tablets, etc.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Tablet
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    LIQUID FORMULATION DEVELOPMENT

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    Piramal offers pharmaceutical formulation development services for liquids and solid dosage forms. It also provides sterile liquids, including injectables and ophthalmics.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Liquid Formulation
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    STERILE LIQUID FORMULATION DEVELOPMENT

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    Piramal offers pharmaceutical formulation development services for sterile liquids (injectables & ophthalmics) and lyophilized drug products from its facilities in the US, the UK and India.

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    Category: Formulation Development

    Sub Category: Sterile Liquid Formulation
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    ORAL DISINTEGRATING TABLET (ODT) DEVELOPMENT

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    Piramal offers pharmaceutical development services for oral solids, including oral disintegrating tablets, sublingual tablets, press-coated tablets, modified-release tablets and oncology drug products (sterile and solid dosages).

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Buccal / Orodispersible
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    CONTROLLED SUBSTANCE DRUG PRODUCTS

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    Piramal engages its global sites to conduct development work in parallel; accelerating time to market and reduce costs. It provides controlled drug substance formulation development in various dosage forms, including solids, liquids & injectables.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Controlled Substance
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    GRANULES FOR RECONSTITUTION

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    Piramal provides formulation development services for oral solids, including tablets, granules for reconstitution along with liquids, creams, ointments and sterile injectables.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Granule / Pellets
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    PEDIATRIC FORMULATION DEVELOPMENT SERVICES

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    Piramal offers pharmaceutical development services for pediatric formulations, oral solids, liquids, creams, ointments and sterile injectables, lyophilized products, etc.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Pediatric Formulation
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    INJECTABLE FORMULATION DEVELOPMENT SERVICES

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    Piramal offers formulation development services for sterile injectables, sterile liquids (injectable & ophthalmic) & lyophilized drug products, along with oral solids, liquids and topical dosage forms from its facilities in the US, the UK & India.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Injectable / Parenteral
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    OPHTHALMIC FORMULATION DEVELOPMENT

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    Piramal seamlessly engages its global sites to conduct development work in parallel; accelerating time to market and reduce costs. Its formulation development services includes sterile liquids, such as ophthalmic & injectable dosage forms.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Ophthalmic
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    STERILE FORMULATIONS - NANOPARTICLES

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    Piramal offers pharmaceutical development services for sterile formulations containing nanoparticles and liposomes from its facilities in the US, the UK & India.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Liposome / Microsphere / Nanoparticle
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    HPAPI DEVELOPMENT & MANUFACTURING SERVICES

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    Piramal is a global leader in the development & manufacturing of high-potent compounds. It has over five decades of experience in HPAPI services with process research, development, optimization and scale-up as well as cGMP manufacturing.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: High Potency APIs (HPAPIs)
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    CDMO FOR PEPTIDE API DEVELOPMENT

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    Piramal is a CDMO peptide API development and manufacturing company that offers solid & solution phase custom peptide synthesis. Its peptide services include peptide development, complex peptide API synthesis along with contract peptide API manufacturing.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Protein / Peptide
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    API DEVELOPMENT SERVICES

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    Piramal's Aurora, Canada, facility is a USFDA, Health Canada & PMDA inspected site which offers development as well as clinical and commercial GMP manufacturing of active pharmaceutical ingredients (APIs) for complex pharmaceutical NCEs.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Overview
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    SYNTHESIS OF INTERMEDIATES & BUILDING BLOCKS

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    Piramal provides synthesis of discrete compounds/focused series, building blocks, intermediates, scale-up of intermediates & final compounds (up to multiple 100 grams), along with synthesis of reference standards/impurities and route scouting activities.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Fine Chemical / Intermediate
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    API CLINICAL SUPPLY

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    Piramal assists its customers with services ranging from process development to optimizing the existing lab-scale process, with expertise in GMP manufacturing of materials to support Phase I to Phase III clinical trials, as well as product registration.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Clinical Supply
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    OZONOLYSIS SERVICES

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    Piramal provides ozonolysis solutions to various customers for development of ozonolysis process, process safety studies and scale-up. A dedicated ozonolysis set up is available for both laboratory-scale (5g/h) work and production (up to 3kg/h) work.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Ozonolysis
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    ROUTE SCOUTING

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    Piramal provides route scouting and other chemistry services. It assists in developing cost-effective, competitively advantaged and robust chemical processes that emphasizes atom efficiency and minimizes waste.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Route Scouting
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    API PROCESS DEVELOPMENT

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    Piramal provides API process development services for pre-clinical and clinical supplies, process/route selection, pre-clinical/clinical (non-GMP and GMP) manufacturing, process engineering & manufacturing support.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Process Development & Optimization
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    DEVELOPMENT OF TOPICAL SEMI-SOLID

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    Apart from OSDs, Piramal also provides manufacturing services for liquids, creams and ointments from its Sellersville, US, facility.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Topical
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    DEVELOPMENT OF CREAMS & OINTMENTS

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    Piramal offers development, manufacturing and packaging services for liquids, creams and ointments from its Sellersville, facility in the US, with maximum capacities of 350 batches, 150 batches and 100 batches, respectively.

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    Pharma Service: API & Drug Product Development

    Category: Formulation Development

    Sub Category: Cream / Gel / Lotion / Ointment
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    PREFORMULATION SERVICES

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    Piramal's preformulation services include pre-clinical candidate characterization, formulation development for testing, clinical phase analytical support & CMC support, including solid-state characterization, polymorph screening, etc.

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    Pharma Service: API & Drug Product Development

    Category: Preformulation & Material Science

    Sub Category: Overview
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    SOLID STATE CHARACTERIZATION

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    Piramal offers CMC support services, such as solid-state characterization, including PXRD, TGA, DSC, Polarized Light Microscope (PLM), Dynamic Vapor Sorption (DVS/hygroscopicity) and Particle Size Analysis (PSA).

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    Pharma Service: API & Drug Product Development

    Category: Preformulation & Material Science

    Sub Category: Solid State Characterization
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    POLYMORPH SCREENING

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    Piramal's preformulation CMC support services include solid-state characterization & polymorph screening, including identification of multiple polymorphs to avoid surprises later in drug development & to identify thermodynamically the most stable form.

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    Pharma Service: API & Drug Product Development

    Category: Preformulation & Material Science

    Sub Category: Polymorph & Crystal Screening
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    BIOANALYTICAL METHOD DEVELOPMENT & VALIDATION

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    Piramal offers bioanalytical services such as method development & validation and bio-sample analysis for small molecules (non-GLP).

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    Pharma Service: Analytical

    Category: BioAnalytical Services

    Sub Category: Method Development and Validation
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    MICROWAVE CHEMISTRY

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    Piramal has specialized chemistry capabilities, including microwave, chiral, aliphatic, aromatic and heterocyclic, carbohydrate, peptide, steroid and nucleoside.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Microwave Chemistry
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    API CONTRACT MANUFACTURING

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    With a successful performance record of over 40 years, Piramal manufactures & supplies active pharmaceutical ingredients (APIs) through its sites in North America, Europe & Asia. Its facilities are approved by the US FDA, Japan PMDA & UK MHRA.

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    Pharma Service: API Manufacturing

    Category: Contract Manufacturing

    Sub Category: Overview
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    HPAPI CONTRACT MANUFACTURING

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    Piramal offers various manufacturing services for high potent APIs (HPAPIs), key starting materials (KSMs), registered starting materials (RSMs), key GMP intermediates and commercial-scale APIs.

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    Pharma Service: API Manufacturing

    Category: High Potency APIs (HPAPIs)

    Sub Category: Overview
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    KEY STARTING MATERIALS & GMP INTERMEDIATES

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    Piramal offers various services such as manufacturing and supply of key starting materials (KSMs), registered starting materials (RSMs), key GMP Intermediates, high potent APIs (HPAPIs) and commercial-scale APIs.

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    Pharma Service: API Manufacturing

    Category: Fine Chemical / Intermediate

    Sub Category: Overview
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    PEPTIDE API MANUFACTURING SERVICES

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    Piramal has been focused on peptide APIs for the last 40 years, offering a legacy of strong capabilities in peptide chemistry. It offers solid- and solution-phase peptide synthesis and manufacturing of long-chain peptide APIs.

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    Pharma Service: API Manufacturing

    Category: Protein / Peptide

    Sub Category: Overview
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    ANTIBODY DRUG CONJUGATE (ADC) MANUFACTURING

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    Piramal has been manufacturing ADCs for over 15 years. It has a world-leading facility for clinical and commercial manufacturing of antibody-drug conjugates (ADCs) and other bioconjugates.

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    Pharma Service: API Manufacturing

    Category: Antibody Drug Conjugate

    Sub Category: Overview
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    CHIRAL CHEMISTRY

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    Piramal has specialized chemistry capabilities, including chiral, aliphatic, aromatic and heterocyclic, carbohydrate, peptide, steroid, nucleoside and microwave.

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    Pharma Service: API Manufacturing

    Category: Chiral Synthesis

    Sub Category: Overview
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    GMP API CONTRACT MANUFACTURING

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    Piramal manufactures & supplies APIs through its sites in North America, Europe & Asia. Its API sites have been inspected & approved by several global regulatory bodies like, the US FDA, Japan PMDA & UK MHRA, and they meet the cGMP compliance standards.

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    API PROCESS DEVELOPMENT SERVICES

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    Piramal has been providing pharmaceutical intermediate and API process development services for nearly three decades from its network of R&D and manufacturing facilities across the globe.

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    Pharma Service: API Manufacturing

    Category: Process Development & Optimization

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    CDMO FOR TABLETS

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    Piramal offers a broad spectrum of special oral solid dosage forms, such as conventional tablets, tablets (film-coated/IR/ER/MR), press-coated tablets (tablet in tablet), bi-layer tablets, controlled & modified-release tablets, etc.

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    MANUFACTURING OF COATED TABLETS

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    Piramal provides a variety of oral solid dosage forms, such as conventional tablets, tablets (film-coated/IR/ER/MR), press-coated tablets (tablet in tablet), bi-layer tablets, modified-release tablets, etc.

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    Sub Category: Coated
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    CDMO FOR MODIFIED RELEASE TABLETS

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    Piramal offers various tablets, such as controlled-release solids (matrix), modified-release tablets, tablets (film-coated/IR/ER/MR), bi-layer tablets, press-coated tablets, etc.

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    Category: Tablet

    Sub Category: Controlled / Immediate / Modified Release
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    HARD GELATIN CAPSULE MANUFACTURING

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    Piramal offers various oral solid dosage forms, such as hard gelatin capsules (powders, granules and pellets), tablets (film-coated/IR/ER/MR), press-coated tablets (tablet in tablet), bi-layer tablets, etc.

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    Pharma Service: Drug Product Manufacturing

    Category: Capsule

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    HORMONAL ORAL SOLID FORMULATIONS

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    Piramal specializes in hormonal and potent oral solid formulations manufactured in a dedicated and segregated suite. It has been handling hormonal products for more than 40 years with experience in hormonal product development and technical transfer.

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    Pharma Service: Drug Product Manufacturing

    Category: Tablet

    Sub Category: Steroid / Hormone
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    STERILE INJECTABLE MANUFACTURING SERVICES

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    Piramal offers cGMP manufacturing of a wide range of parenteral drug products including sterile solutions and suspensions (aqueous/non-aqueous) in liquid and lyophilized dosage forms.

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    Pharma Service: Drug Product Manufacturing

    Category: Injectable / Parenteral

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    CLINICAL & COMMERCIAL SUPPLY OF INJECTABLES

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    Piramal offers clinical & commercial manufacturing of liquid & lyophilized formulations. It provides sterile solutions & suspensions (aqueous/non-aqueous), nanoparticles and liposomes, liquid and lyophilized dosage forms.

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    Category: Injectable / Parenteral

    Sub Category: Clinical Supply
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    CDMO FOR CREAMS & OINTMENTS

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    Apart from OSDs, Piramal also provides liquids, creams and ointments. It offers development, manufacturing & packaging services for liquids, creams and ointments with maximum capacities of 350 batches, 150 batches and 100 batches, respectively.

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    Pharma Service: Drug Product Manufacturing

    Category: Cream / Lotion / Ointment

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    HIGHLY POTENT ORAL LIQUID FORMULATIONS

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    Piramal can help you safely & efficiently turn your HPAPI project into a success. It specializes in formulating highly toxic compounds, such as cytotoxics, hormones, HPAPIs & controlled substances, into safe & effective oral liquids & solid dosage forms.

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    Sub Category: High Potency APIs (HPAPIs)
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    ANTIBODY DRUG CONJUGATE FILL & FINISH

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    Piramal is a global leader in delivering customer-centric solutions in the field of Antibody Drug Conjugates (ADCs) and other bioconjugates. It provides aseptic filling of ADC and bioconjugate drug products through its FDA-approved manufacturing facility.

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    Category: Biologic Drugs

    Sub Category: Antibody Drug Conjugate
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    CONTROLLED SUBSTANCE ORAL SOLIDS

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    Piramal specializes in formulating highly toxic compounds, such as cytotoxics, hormones, HPAPIs and controlled substances, into safe & effective oral solid dosage forms.

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    Category: Tablet

    Sub Category: Controlled Substance
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    HPAPI TABLET MANUFACTURING

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    Piramal specializes in formulating highly toxic compounds, such as HPAPIs, controlled substances, cytotoxics and hormones, into safe & effective oral solid dosage forms.

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    Category: Tablet

    Sub Category: High Potency APIs (HPAPIs)
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    CLINICAL PACKAGING SERVICES

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    Piramal offers clinical trial packaging, such as primary (solid-dose bottling & multi-dose blistering) and secondary packaging (labelling, artwork design, translation services, label printing).

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    CLINICAL (GMP) MANUFACTURING

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    Piramal pharmaceutical contract manufacturing services support the drug discovery process through the manufacturing of advanced chemical intermediates and active pharmaceutical ingredients (API) for all clinical phases.

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    Pharma Service: API Manufacturing

    Category: Clinical Supply

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    CDMO FOR ANTIBODY DRUG CONJUGATES (ADCs)

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    Piramal offers contract development and manufacturing of Antibody-Drug Conjugates (ADCs) and other bioconjugates. It has robust process development, optimization, and scale-up expertise supporting successful GMP manufacturing.

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    Pharma Service: API & Drug Product Development

    Category: API Development

    Sub Category: Antibody Drug Conjugate
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