Please Wait
Applying Filters...

Renejix Renejix


Looking for a contract manufacturer for capsule manufacturing services? Find CDMO, CMO offering hardgel, softgel, veg capsule, etc. on PharmaCompass

Filters Filter
Cross PopUp


01 Clinical Supply

02 Clinical Supply

03 Clinical Supply

04 Clinical Supply

05 Clinical Supply

06 Controlled / Immediate / Modified Release

07 Controlled / Immediate / Modified Release

08 Controlled / Immediate / Modified Release

09 Controlled / Immediate / Modified Release

10 Controlled / Immediate / Modified Release

11 Controlled / Immediate / Modified Release

12 Controlled / Immediate / Modified Release

13 Controlled Substance

14 Controlled Substance

15 Controlled Substance

16 Controlled Substance

17 Enteric Coated

18 Enteric Coated

19 Hard Capsule

20 Hard Capsule

21 Hard Capsule

22 Hard Capsule

23 Hard Capsule

24 Hard Capsule

25 High Potency APIs (HPAPIs)

26 High Potency APIs (HPAPIs)

27 High Potency APIs (HPAPIs)

28 High Potency APIs (HPAPIs)

29 Immediate Release

30 Immediate Release

31 Modified Release

32 Modified Release

33 Modified Release

34 Modified Release

35 Oral

36 Oral

37 Overview

38 Overview

39 Overview

40 Overview

41 Overview

42 Overview

43 Overview

44 Overview

45 Overview

46 Overview

47 Overview

48 Overview

49 Overview

50 Overview

51 Overview

52 Overview

53 Overview

54 Steroid / Hormone

55 Vegetarian

56 Vegetarian


01 AJES Pharmaceuticals, LLC


03 AbbVie Contract Manufacturing

04 Adare Pharma Solutions

05 Aenova Group

06 Aesica Pharmaceuticals Limited

07 AlbyPharma

08 Ardena

09 Athena Pharmaceutiques

10 Atral

11 Aurigene Pharmaceutical Services

12 Avara Pharmaceutical Services

13 Axxelent Pharma Science


15 Bioindustria L.I.M. Spa

16 Biological E

17 Biopharma Srl

18 Biophore India Pharmaceuticals Pvt Ltd

19 Bioplus Life Sciences

20 Bliss Gvs Pharma Ltd

21 Bluepharma

22 Bora Pharmaceuticals

23 Cambrex Corporation

24 Catalent Pharma Solutions

25 Chanelle Medical

26 Curtis Health Caps

27 Custom Pharma Services

28 Cyndea Pharma S.L

29 Delorbis Pharmaceuticals

30 Delpharm Group

31 Douglas Pharmaceuticals

32 Ethypharm

33 Eurofins CDMO

34 Famar

35 Farbe Firma

36 Fareva

37 Fermion Oy

38 Flagship Biotech International Pvt. Ltd

39 Fresenius Kabi Austria

40 Fulton Medicinali S.p.A

41 Gensenta Pharmaceuticals

42 Glatt Pharmaceutical Services

43 Global Pharma CM Sp. z o. o

44 Globela Pharma

45 Gracure Pharmaceuticals Limited

46 Grunenthal


48 Humanis

49 JGL d.d

50 JSC Olainfarm

51 Juniper Pharmaceuticals, Inc

52 Kampotu

53 LGM Pharma

54 Labiana Pharmaceuticals

55 Laboratoires Galéniques Vernin

56 Lecifarma

57 Lifecare Neuro Products

58 Lonza Capsugel

59 Madras Pharmaceuticals

60 Mikart

61 Mithra CDMO

62 Mycon Pharma

63 Nanjing Dorra Pharmaceutical Technology Co.,Ltd


65 Olive Healthcare

66 One Pharma

67 Orchid Pharma

68 Orofino Pharmaceuticals Group

69 Osmopharm

70 Panacea Biotec Limited

71 Pfizer CentreOne

72 Pierre Fabre

73 Piramal Pharma Solutions

74 Prague Scientific

75 Priyans Drugs

76 Quotient Sciences

77 R-Pharm Germany GmbH

78 Rafarm S.A

79 Recipharm AB

80 Renejix

81 Renown Pharmaceuticals

82 Ropack Inc

83 S.C. Rompharm Company SRL

84 Santa S.A

85 Servier

86 Sharp

87 Siegfried AG

88 Sirio Pharma Co. Ltd

89 Skyepharma

90 Societal CDMO

91 Sofarimex

92 Softigel Procaps

93 Solistaa Pharmaceuticals

94 Stason Pharmaceuticals, Inc.

95 Sterling Pharma

96 Temad Co

97 Tianjin Hankang Pharmaceutical Biotechnology

98 Torrent Pharmaceuticals Limited

99 UPM Pharmaceuticals

100 Vici Health Sciences

101 WellSpring Consumer Healthcare


01 Austria

02 Belgium

03 China

04 China

05 Colombia

06 Croatia

07 Cyprus

08 Czech Republic

09 Finland

10 France

11 France

12 France

13 France

14 Germany

15 Greece

16 Greece

17 Greece

18 India

19 India

20 India

21 Iran

22 Ireland

23 Italy

24 Latvia

25 Luxembourg

26 New Zealand

27 Poland

28 Portugal

29 Romania

30 Singapore

31 Spain

32 Sweden

33 Switzerland

34 Taiwan

35 Turkey

36 Turkey

37 U.S.A

38 U.S.A

39 U.S.A

40 U.S.A

41 U.S.A

42 U.S.A

43 U.S.A

44 United Kingdom

45 United Kingdom

List of Learn MoreList of #LearnMore

Looking for a contract manufacturer for capsule manufacturing services? Find CDMO, CMO offering hardgel, softgel, veg capsule, etc. on PharmaCompass

Q1. Capsules, what are they and what are the advantages?

In the pharmaceutical industry, capsules refer to solid dosage forms in which the drug is enclosed in a hard or soft soluble container. Capsules are usually administered orally, but occasionally may be administered rectally or vaginally. 

Orally administered medications are hands down, the world’s preferred way to take medicines. For developers, oral solid dosage or OSD forms like tablets and capsules remain the preferred administration route due to their cost-effectiveness, relative ease of manufacturing and the wide availability of patient-friendly dosing options.

Capsules are generally made from special film-forming materials (such as gelatin, cellulose, polysaccharides, and pure natural plant starch, etc.), which are used to enclose ingredients in a relatively stable shell, allowing them to be taken orally.

Capsules may also be filled with a range of formulation types including dry powders, semisolids, nonaqueous liquids, and other dosage forms such as beads, mini-tablets, and even mini capsules.

Therefore, various types of capsules, with shells and inner fills made of different materials, are available in the market. Traditional capsules are principally made from gelatin, which is a common ingredient in medicines and food products. 


Some Advantages of Capsules

- Capsules are tasteless, odorless, and can be administered easily. Drugs with unpleasant tastes and odors may also be enclosed in tasteless shells to make them more attractive to consumers.

- If properly stored the shells contain 12-15% of moisture which give flexibility and consequently very considerable resistance to mechanical stresses.

- Capsules can accommodate combinations of powders, and physicians may change the dose and combination of a capsule drug according to patient requirements.

- Presentation of a drug in a capsule rather than in tablets, allows quicker submission of a new drug for clinical trials because fewer development problems are involved.

- Other advantages of the capsule include the ability of an effective oxygen barrier and excellent chemical stability, which could improve product stability. For example, components that are unstable, sensitive to temperature, light and heat can be made into capsule forms.

Q2. What are the different types of capsules and what are their components?

Capsules are the dosage forms in which a drug formulation usually in a powder, semisolid, or liquid form is enclosed in a shell. This capsule shell is generally made from gelatin but can be made from other polymers such as hydroxypropyl methylcellulose (vegan capsules), polyvinyl alcohol (PVA), seaweed, or starch.

While there are a wide variety of capsules available in the pharmaceutical industry, hard capsules and soft capsules are the two most prolific capsule types in the market. Softgel capsules and hard gel capsules as well as their corresponding components are explored in detail below. 


Softgel Capsules

Soft gelatin capsules, also known as softgels or soft elastic capsules, are hermetically sealed one-piece capsules containing a liquid or a semisolid fill without an air or gas bubble. Softgels consist of two parts: solid capsule (outer shell) and a liquid or semi-solid center (inner fill). There are various softgel contract manufacturers that offer softgel capsule contract manufacturing services.

Softgel capsules offer several advantages such as delivering a liquid matrix designed to solubilize and improve the oral bioavailability of a poorly soluble compound, delivering low and ultra-low doses of a compound, delivering a low melting compound, and minimizing potential generation of dust during manufacturing, etc.

- Some Soft Capsule Outer Shell Ingredients

- Gelatin (e.g. bovine, porcine, piscine)

- Plasticizer (e.g. glycerin, sorbitol)

- Solvent (e.g. water)

- Flavoring agents (e.g. essential oils, sucrose)

- Colorants (e.g. dye, lakes)

- Preservatives (e.g. antioxidant agents, antimicrobial agents)

- Other additives

- Some Soft Capsule Inner Fill Materials

- Oily Mixtures

- Solutions

- Suspensions


Hard Gelatin Capsules

Hard capsules are rigid, cylindrical shells typically made of two parts - the body and the cap - which are filled with dry or liquid ingredients and then specially sealed to prevent leakages. These are one of the oldest forms of the pharmaceutical capsule.

Hard capsules also offer several advantages: they are less expensive, easy to fill, able to meet different demands, have a longer shelf life, are easily digestible, have better bioavailability compared to tablets and allow a better degree of flexibility, amongst several other benefits.

- Some Hard Capsule Outer Shell Ingredients

- Gelatin (e.g. Type A and Type B)

- Colorants (e.g. dye, lakes, mineral colors)

- Opacifiers (e.g. Tio2)

- Plasticizer (e.g. sorbitol, glycerin)

- Preservatives (e.g. propyl and methyl parabens)

- Some Hard Capsule Inner Fill Materials

- Dry powders

- Granules

- Pellets


Some Other Types of Capsules

- Veg Capsule or Vegan Capsule 

HPMC capsules or veg capsules are two-piece capsules that serve as vegetarian alternatives to hard gelatin capsules and satisfy certain dietary and cultural needs. HPMC used in veg capsules or vegan capsules is considered safe for normal human consumption.

- Chewable Capsule

Chewable capsules are capsules designed to be chewed to release the active and/or inert ingredients. Chewable capsules are a versatile dosage form offering several advantages including oral drug delivery without the need for water, ease of swallowing, the stability advantages of solid dosage forms, and patient-centric drug delivery.

Q3. What are the different steps involved in manufacturing capsules?

Capsule manufacturing starts with the dispense of raw materials, which then undergoes the process of granulation where sieving is done and various binders are added. This is followed by drying, sizing and blending of the materials. 

This material then undergoes capsule filling techniques after which it goes for capsule polishing. After all that the capsules go for primary packaging (e.g. blister packaging) and then secondary packaging. 


Manufacturing Capsules - Hard Gelatin Capsules

Hard gelatin capsules are fabricated and supplied empty to the pharmaceutical industry by empty shell suppliers, and are then filled in a separate operation. Manufacturing capsules involves a step by step process that requires strict quality control in the manufacture of hard gelatin capsules.

- Hard Gel Capsule Manufacturing Steps

Step 1: Preparation of gelatin solution (dipping solution)

Step 2: Dip-coating the gelatin solution on to metal pins (moulds)

Step 3: Rotation of the dip-coated pins

Step 4: Drying of the gelatin-coated pins

Step 5: Stripping and trimming

Step 6: Joining of the trimmed capsule shell

Step 7: Printing

Step 8: Developing and preparing the inner fill formulation

Step 9: Capsule filling using manual, semi automatic or automatic filling devices

Step 10: Sealing the filled hard capsules

Step 11: Cleaning and polishing the dry filled capsules


Manufacturing Capsules - Softgels

Soft gelatin capsules are made from a more flexible, plasticized gelatin film than hard gelatin capsules. A softgel consists of a gelatin-based shell surrounding a liquid fill. The shells are a combination of gelatin, water, opacifier, and a plasticizer, such as glycerin or sorbitol. In the encapsulation process, two flat ribbons are manufactured and brought together on a twin set of rotating dies.

- Softgel Capsule Manufacturing Steps 

Step 1: Raw material storage and selection

Step 2: Weighing softgel capsule ingredients for inner and outer fills

Step 3: Preparation of inner fill materials 

Step 4: Softgel encapsulation (Softgel capsule filling services)

Step 5: Drying

Step 6: Softgel dosage form inspection

Step 7: Soft shell capsule packaging

Step 8: Finished product storage and distribution

Q4. Which are the leading pharma contract manufacturers offering capsules?

Some leading pharma contract manufacturers or capsule contract manufacturers that offer custom formulation and product development services for capsules, capsule filling techniques, (e.g. softgel capsule filling services), softgel capsule contract manufacturing and hard capsule contract manufacturing are noted below.


AbbVie Contract Manufacturing - Capsule Contract Manufacturing

AbbVie Contract Manufacturing, a leading pharma contract manufacturer and developer, offers contract manufacturing of various oral solid dosage forms such as capsules, over-encapsulation, bi-layer tablets, mini and micro tablets, liquids, pellets, granules, etc.

AbbVie Contract Manufacturing manufactures and packages finished drug products, with specific expertise in producing tablets, capsules, liquid-filled capsules, granules, prefilled syringes and oral liquids. Their manufacturing expertise includes tablet coating, spray coating, drying granulation, etc.

Skyepharma - Capsule Filling and Packaging

Skyepharma’s capsule manufacturing capabilities include capsules filled with tablets, granules, pellets, or powders. They offer blister packaging in PVC, PVDC, Aclar, Triplex, etc. and blister packaging services including serialization and aggregation. They also offer custom formulation and product development services for capsules and other dosage forms.

Pfizer CentreOne - Capsule Filling and Packaging

Pfizer CentreOne offers flexible oral solid dose manufacturing with various delivery technologies of capsules such as immediate-release capsules, modified-release capsules, powder-filled capsules, pellet-filled capsules, etc. It also offers other capsule filling and packaging services such as coating, blending, etc.

Polpharma - Hard Capsule Manufacturing

Polpharma is a leading capsule contract manufacturer offering contract manufacturing for various oral solid dosage forms such as hard gelatin capsules (filled with powders, pellets, granules) using various capsule filling techniques, soft gelatin capsules (i.e. softgel capsule contract manufacturing along with softgel capsule filling services), tablets, multilayer tablets, film and sugar coated tablets.

Its site in New Doba, Poland specializes in contract manufacturing dry oral formulations, including producing and packing tablets, coated tablets and hard gelatin capsules, in blisters (blister packaging) and polyethylene containers.

Recipharm AB - Hard Capsule Manufacturing

Recipharm has the capabilities to deliver your project from development through to the manufacture of large commercial batch sizes of tablets, capsules, hard gelatin capsules and powders. It is a leading capsule contract manufacturer offering custom formulation and product development services for capsules and various other dosage forms.