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Find Clinical Drug Pipeline Developments & Deals by Piramal Pharma Solutions
Doxycycline for Injection, USP is a Protein 30S ribosomal subunit inhibitor, which is used for prevent infections that are proven or strongly suspected to be caused by susceptible bacteria.
Under the agreement, Piramal will produce additional cGMP liposome intermediate drug product to meet the increase in demand for its lead investigational targeted radiotherapeutic, rhenium (186Re) obisbemeda, for ongoing and planned clinical trials.
Zinc Sulfate is a trace element indicated as a source of zinc for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
The two Companies envision that the MSA will lead to clinical and commercial supply agreements for the drug product 186RNL (rhenium liposome) at the appropriate stage of development.
Piramal Pharma Solutions (PPS) is providing drug product formulation and manufacturing from the company’s Lexington, KY site in the U.S. Drug product material will be used in a first-in-humans clinical study for TH1902.
The clinical material is produced at the Piramal Pharma manufacturing site, which is recognized globally for its expertise in sterile fill/finish services. It will be used in a Phase I trial for TH1902, Theratechnologies’ lead peptide-drug conjugate (docetaxel conjugate).
Epirium has advanced its first clinical candidate EPM-01 (Epicatechin) in Becker muscular dystrophy and plans to follow with drug development targeting other disorders associated with mitochondrial dysfunction and tissue degeneration.
The Piramal Pharma Solutions team is applying its integrated drug development model to Bolt’s BDC-1001 for the treatment of patients with HER2-expressed solid tumors. The program encompasses formulation development and ISAC development and manufacture.