Isavuconazonium Sulfate API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

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API | Excipient name

Isavuconazonium Sulfate

Synonyms

946075-13-4, Cresemba, Isavuconazonium (sulfate), Bal-8557-002, Isavuconazonium sulfate [usan], Chebi:85977

Cas Number

946075-13-4

Unique Ingredient Identifier (UNII)

31Q44514JV

About Isavuconazonium Sulfate

Isavuconazonium Sulfate is the sulfate ester form of isavuconazonium, a prodrug of the triazole antifungal agent isavuconazole, with broad-spectrum antifungal activity. Upon administration, isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), which catalyzes the demethylation of lanosterol to yield ergosterol, an important component of the fungal cell membrane. Inhibition of CYP51 leads to a decrease in fungal ergosterol production and disrupts synthesis of the fungal cell membrane, which decreases membrane integrity, increases cell membrane permeability and promotes the loss of essential intracellular elements. This results in fungal cell lysis and death.

Isavuconazonium Sulfate Manufacturers

A Isavuconazonium Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Isavuconazonium Sulfate, including repackagers and relabelers. The FDA regulates Isavuconazonium Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Isavuconazonium Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

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Isavuconazonium Sulfate Suppliers

A Isavuconazonium Sulfate supplier is an individual or a company that provides Isavuconazonium Sulfate active pharmaceutical ingredient (API) or Isavuconazonium Sulfate finished formulations upon request. The Isavuconazonium Sulfate suppliers may include Isavuconazonium Sulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Isavuconazonium Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Isavuconazonium Sulfate Manufacturers | Traders | Suppliers

We have 32 companies offering Isavuconazonium Sulfate

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of all Manufacturers, Suppliers & Exporters of Isavuconazonium Sulfate API listed on PharmaCompass with details of regulatory filings