Details:
NanoAbs (alpaca-derived nanosized antibody) also known as VHH-antibodies, exhibit potential as biobetter therapies for a wide range of diseases. Scinai is developing NanoAbs addressing diseases with large unmet medical needs and attractive commercial opportunities, such as psoriasis.
Lead Product(s): Alpaca-derived Nanosized Antibody
Therapeutic Area: Dermatology Product Name: NanoAbs
Highest Development Status: Preclinical Product Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 13, 2023
Details:
The company develops topical and oral drugs based on proprietary small molecules that inhibit an ion channel designated TRPV3. These drugs are intended for the treatment of various dermatological diseases.
Lead Product(s): Undisclosed
Therapeutic Area: Dermatology Product Name: Undisclosed
Highest Development Status: Preclinical Product Type: Small molecule
Partner/Sponsor/Collaborator: GIBF2
Deal Size: $8.0 million Upfront Cash: Undisclosed
Deal Type: Financing September 19, 2022
Details:
Maruho also entered into a binding agreement for an equity investment in BiomX of $3 million at a premium to the market share price, intended primarily to support the Phase 1/2 study of atopic dermatitis product candidate, BX005, in Japan.
Lead Product(s): BX005
Therapeutic Area: Dermatology Product Name: BX005
Highest Development Status: Preclinical Product Type: Large molecule
Partner/Sponsor/Collaborator: Maruho
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Agreement October 13, 2021
Details:
In vitro results with BX005 demonstrated a broad host range and efficient eradication of Staphylococcus aureus strains with no mutants arising after 24 hours, versus untreated strains showing normal growth.
Lead Product(s): BX005
Therapeutic Area: Dermatology Product Name: BX005
Highest Development Status: Preclinical Product Type: Large molecule
Partner/Sponsor/Collaborator: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable June 14, 2021