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Find Drugs for Cardiology/Vascular Diseases in Phase I Clinical Development in UNITED STATES

A collaboration with SCORR Marketing

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            Lead Product(s): AMG 594

            Therapeutic Area: Cardiology/Vascular Diseases

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 03, 2020

            Details:

            In vitro studies demonstrate cardiac troponin activator selectively activates cardiac muscle fibers with little effect on slow skeletal muscle or fast skeletal muscle.

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            Lead Product(s): ARO-APOC3

            Therapeutic Area: Cardiology/Vascular Diseases

            Highest Development Status: Phase I Product Type: Undisclosed

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 05, 2020

            Details:

            Multiple-dose data across various patient populations show marked improvement in multiple lipid parameters.

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            Lead Product(s): NAN-101

            Therapeutic Area: Cardiology/Vascular Diseases

            Highest Development Status: Phase I Product Type: Gene therapy

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 04, 2020

            Details:

            AskBio dosed first patient in a Phase 1 clinical trial of NAN-101. The aim of the study is to identify potential therapeutic targets to restore heart function.

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            Lead Product(s): APD418

            Therapeutic Area: Cardiology/Vascular Diseases

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 16, 2020

            Details:

            APD418 currently in Phase 1 clinical investigation - data expected this year.

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            Lead Product(s): CK-3773274

            Therapeutic Area: Cardiology/Vascular Diseases

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable January 06, 2020

            Details:

            REDWOOD-HCM is a Phase 2 clinical trial of CK-3773274 (CK-274), a next-generation cardiac myosin inhibitor discovered by company scientists, which Cytokinetics is developing for the potential treatment of (HCM).