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therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Neurology","graph2":"Discovery","graph3":"Amgen Inc","amount2":0.10000000000000001,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Neurology","amount2New":0.10000000000000001,"dosageForm":"Undisclosed","sponsorNew":"Amgen Inc \/ Amgen Inc","highestDevelopmentStatusID":"2","companyTruncated":"Amgen Inc \/ Amgen Inc"},{"orgOrder":0,"company":"Amgen Inc","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Uplizna","moa":"B-lymphocyte antigen CD19","graph1":"Undisclosed","graph2":"Undisclosed","graph3":"Amgen Inc","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amgen Inc \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Amgen Inc \/ Inapplicable"},{"orgOrder":0,"company":"Amgen Inc","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Undisclosed","country":"U.S.A","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"AMG701","moa":"BCMA receptor","graph1":"Undisclosed","graph2":"Undisclosed","graph3":"Amgen Inc","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Amgen Inc \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Amgen Inc \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Amgen Inc

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                            01

                            Amgen Inc

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                            Lead Product(s) : Inebilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves Amgen's Uplizna as First Treatment for Rare Immune Disorder

                            Details : Uplizna (inebilizumab) is a CD19-directed cytolytic antibody which is being investigated for the treatment of pattients with Immunoglobulin G4-related disease.

                            Product Name : Uplizna

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 03, 2025

                            Lead Product(s) : Inebilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Amgen Inc

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                            Lead Product(s) : YL201

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Medilink

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Partic...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Large Molecule

                            Upfront Cash : Inapplicable

                            March 27, 2025

                            Lead Product(s) : YL201

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Medilink

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Amgen Inc

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                            Lead Product(s) : Rocatinlimab

                            Therapeutic Area : Dermatology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Amgen and Kyowa Kirin Report Top-Line Results from Rocatinlimab Phase 3 Study

                            Details : AMG 451 (rocatinlimab) is an anti-OX40 mAb that inhibits and reduces the number of OX40+ pathogenic T cells responsible for driving systemic and local atopic dermatitis inflammatory responses.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 08, 2025

                            Lead Product(s) : Rocatinlimab

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Amgen Inc

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                            Lead Product(s) : Tarlatamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : University of Arizona

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 07, 2025

                            Lead Product(s) : Tarlatamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : University of Arizona

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Amgen Inc

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                            Lead Product(s) : Etakafusp Alpha,Tarlatamab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Asher Biotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Asher Bio, BeiGene Collaborate on AB248, T-Cell Engager for Lung Cancer

                            Details : As part of this collaboration agreement, Amgen will sponsor a global Phase 1b study to evaluate the early efficacy of AB248 (etakafusp alfa) in combination with Imdelltra in patients with ES-SCLC.

                            Product Name : Undisclosed

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            January 08, 2025

                            Lead Product(s) : Etakafusp Alpha,Tarlatamab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Asher Biotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            06

                            Amgen Inc

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                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Trial to Investigate Teprotumumab (High-concentration Formulation) Subcutaneous Administration in Healthy Ad...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 05, 2024

                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Recipient : Xeris Pharmaceuticals

                            Deal Size : $75.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Xeris Biopharma Signs Worldwide License Deal for Xeriject Formulation of Teprotumumab

                            Details : Under the agreement, Amgen will develop, manufacture, and commercialize a subcutaneous formulation of Tepezza (teprotumumab) using Xeris’ XeriJect® technology in Thyroid Eye Disease (TED).

                            Product Name : Tepezza

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            October 01, 2024

                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Recipient : Xeris Pharmaceuticals

                            Deal Size : $75.0 million

                            Deal Type : Licensing Agreement

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                            08

                            Amgen Inc

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                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Undisclosed

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study of TEPEZZA Subcutaneous Administration in Healthy Adults

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 21, 2024

                            Lead Product(s) : Teprotumumab

                            Therapeutic Area : Undisclosed

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Amgen Inc

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                            Lead Product(s) : CX-904

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : CytomX Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CytomX Announces Positive Phase 1a Data for Monotherapy CX-904 PROBODY® T-Cell Engager

                            Details : CX-904 is a PROBODY T-cell engager targeting EGFR on cancer cells and CD3 on T cells, being evaluated for advanced pancreatic cancer.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 05, 2024

                            Lead Product(s) : CX-904

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : CytomX Therapeutics

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Amgen Inc

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                            Lead Product(s) : Tarlatamab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Pri...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            July 16, 2024

                            Lead Product(s) : Tarlatamab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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