Synopsis
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1. Ta-8995
1. Ta-8995
2. 866399-87-3
3. Obicetrapib (free Base)
4. Amg-899
5. Dez-001
6. Obicetrapib [inn]
7. 8o74k609hn
8. 866399-87-3 (free Base)
9. (2r,4s)-4-((3,5-bis(trifluoromethyl)benzyl)(5-(3-carboxypropoxy)pyrimidin-2-yl)amino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2h-quinoline-1-carboxylic Acid Ethyl Ester
10. 1(2h)-quinolinecarboxylic Acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl)(5-(3-carboxypropoxy)-2-pyrimidinyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, 1-ethyl Ester, (2r,4s)-
11. 1-ethyl (2r,4s)-4-[[[3,5-bis(trifluoromethyl)phenyl]methyl][5-(3-carboxypropoxy)-2-pyrimidinyl]amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-1(2h)-quinolinecarboxylate
12. 4-((2-(((3,5-bis(trifluoromethyl)phenyl)methyl)((2r,4s)-1- (ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4- Tetrahydroquinolin-4-yl)amino)pyrimidin-5-yl)oxy)butanoic Acid
13. 4-((2-((3,5-bis(trifluoromethyl)benzyl)((2r,4s)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl)amino)pyrimidin-5-yl)oxy)butanoic Acid
14. 4-[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-[(2r,4s)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2h-quinolin-4-yl]amino]pyrimidin-5-yl]oxybutanoic Acid
15. Obicetrapib [who-dd]
16. Unii-8o74k609hn
17. Chembl3785197
18. Schembl17002081
19. Gtpl12205
20. Ex-a6112
21. Ta8995
22. Obicetrapib (amg-899,ta-8995)
23. Db14890
24. Ac-35552
25. Hy-18778
26. Q27270811
| Molecular Weight | 722.6 g/mol |
|---|---|
| Molecular Formula | C32H31F9N4O5 |
| XLogP3 | 7.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 17 |
| Rotatable Bond Count | 12 |
| Exact Mass | 722.21507356 g/mol |
| Monoisotopic Mass | 722.21507356 g/mol |
| Topological Polar Surface Area | 105 Ų |
| Heavy Atom Count | 50 |
| Formal Charge | 0 |
| Complexity | 1100 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
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Obicetrapib is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Hyperlipidemias.
Lead Product(s): Obicetrapib,Ezetimibe
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable October 22, 2025

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Lead Product(s) : Obicetrapib,Ezetimibe
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Study Evaluates Obicetrapib Combo in Diabetes or Metabolic Syndrome
Details : Obicetrapib is a small molecule drug candidate, which is currently being evaluated in Phase III clinical studies for the treatment of Hyperlipidemias.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 22, 2025

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Obicetrapib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of unspecified medical condition.
Lead Product(s): Obicetrapib,Inapplicable
Therapeutic Area: Undisclosed Brand Name: Undisclosed
Study Phase: Phase IIProduct Type: Miscellaneous
Sponsor: MB Clinical Research and Consulting
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable May 21, 2025

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Lead Product(s) : Obicetrapib,Inapplicable
Therapeutic Area : Undisclosed
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : MB Clinical Research and Consulting
Deal Size : Inapplicable
Deal Type : Inapplicable
Obicetrapib Effect on Antioxidant Levels in Plasma & HDL in Healthy Volunteers
Details : Obicetrapib is a Other Small Molecule drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of unspecified medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 21, 2025

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TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Lead Product(s): Obicetrapib,Ezetimibe
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: NewAmsterdam Pharma
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 16, 2024

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Lead Product(s) : Obicetrapib,Ezetimibe
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : NewAmsterdam Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Menarini’s Obicetrapib Trials Show Positive Phase 3 Data for Cholesterol Reduction
Details : TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 16, 2024

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Details:
The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Lead Product(s): Obicetrapib,Inapplicable
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Jefferies
Deal Size: $452.6 million Upfront Cash: Undisclosed
Deal Type: Public Offering December 13, 2024

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Lead Product(s) : Obicetrapib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Jefferies
Deal Size : $452.6 million
Deal Type : Public Offering
NewAmsterdam Closes $479M Upsized Offering With Full Exercise Of Underwriters’ Option
Details : The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 13, 2024

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Details:
The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Lead Product(s): Obicetrapib,Inapplicable
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Jefferies
Deal Size: $416.5 million Upfront Cash: Undisclosed
Deal Type: Public Offering December 11, 2024

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Lead Product(s) : Obicetrapib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Jefferies
Deal Size : $416.5 million
Deal Type : Public Offering
NewAmsterdam Prices $416.5 Million Upsized Offering Of Shares And Pre-Funded Warrants
Details : The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 11, 2024

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
Details:
The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Lead Product(s): Obicetrapib,Inapplicable
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Jefferies
Deal Size: $300.0 million Upfront Cash: Undisclosed
Deal Type: Public Offering December 10, 2024

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Obicetrapib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Jefferies
Deal Size : $300.0 million
Deal Type : Public Offering
NewAmsterdam Pharma Begins $300 Million Offering Of Shares And Pre-Funded Warrants
Details : The net proceeds will be to advance the clinical development of TA-8995 (obicetrapib), which is being evaluated in the late-stage trial studies for the treatment of Atherosclerosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 10, 2024

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Details:
TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Lead Product(s): Obicetrapib,Ezetimibe
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 10, 2024

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Obicetrapib,Ezetimibe
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
NewAmsterdam Pharma Announces Phase 3 BROADWAY Trial Data for Obicetrapib
Details : TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 10, 2024

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.
Details:
TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Lead Product(s): Obicetrapib,Ezetimibe
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 20, 2024

Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass.
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Lead Product(s) : Obicetrapib,Ezetimibe
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
NewAmsterdam Releases Phase 3 TANDEM Data for Obicetrapib-Ezetimibe in ASCVD Patients
Details : TA-8995 (obicetrapib), CETP inhibitor, in combination with Ezetimibe, is being evaluated for the treatment of Heterozygous Familial Hypercholesterolemia, Atherosclerotic Cardiovascular Disease.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 20, 2024

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Details:
Obicetrapib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Lead Product(s): Obicetrapib,Ezetimibe
Therapeutic Area: Undisclosed Brand Name: Undisclosed
Study Phase: Phase IProduct Type: Miscellaneous
Sponsor: Pharma Medica Research
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable August 09, 2024

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Lead Product(s) : Obicetrapib,Ezetimibe
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Partner/Sponsor/Collaborator : Pharma Medica Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Obicetrapib is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of undefined medical condition.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 09, 2024

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Details:
TA-8995 (obicetrapib) is a next-generation, non statin, oral once-daily, low-dose CETP inhibitor. It is currently being investigated in adult patients with Heterozygous Familial Hypercholesterolemia.
Lead Product(s): Obicetrapib,Inapplicable
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: Undisclosed
Study Phase: Phase IIIProduct Type: Miscellaneous
Sponsor: NewAmsterdam Pharma
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable July 26, 2024

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Lead Product(s) : Obicetrapib,Inapplicable
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : NewAmsterdam Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
NewAmsterdam Pharma to Announce Phase 3 Data for Obicetrapib in Hypercholesterolemia
Details : TA-8995 (obicetrapib) is a next-generation, non statin, oral once-daily, low-dose CETP inhibitor. It is currently being investigated in adult patients with Heterozygous Familial Hypercholesterolemia.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 26, 2024

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15 Oct 2024

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ABOUT THIS PAGE
17
PharmaCompass offers a list of Obicetrapib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Obicetrapib manufacturer or Obicetrapib supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Obicetrapib manufacturer or Obicetrapib supplier.
A Obicetrapib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Obicetrapib, including repackagers and relabelers. The FDA regulates Obicetrapib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Obicetrapib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Obicetrapib manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.
A Obicetrapib supplier is an individual or a company that provides Obicetrapib active pharmaceutical ingredient (API) or Obicetrapib finished formulations upon request. The Obicetrapib suppliers may include Obicetrapib API manufacturers, exporters, distributors and traders.
click here to find a list of Obicetrapib suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.
Obicetrapib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Obicetrapib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Obicetrapib GMP manufacturer or Obicetrapib GMP API supplier for your needs.
A Obicetrapib CoA (Certificate of Analysis) is a formal document that attests to Obicetrapib's compliance with Obicetrapib specifications and serves as a tool for batch-level quality control.
Obicetrapib CoA mostly includes findings from lab analyses of a specific batch. For each Obicetrapib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Obicetrapib may be tested according to a variety of international standards, such as European Pharmacopoeia (Obicetrapib EP), Obicetrapib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Obicetrapib USP).