Sacubitril-Valsartan API Manufacturers | Suppliers | Drug Master Files (DMF) | CEP

PharmaCompass offers a list of Sacubitril-Valsartan API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Sacubitril-Valsartan manufacturer or Sacubitril-Valsartan supplier for your needs.

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PharmaCompass also assists you with knowing the Sacubitril-Valsartan API Price utilized in the formulation of products. Sacubitril-Valsartan API Price is not always fixed or binding as the Sacubitril-Valsartan Price is obtained through a variety of data sources. The Sacubitril-Valsartan Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Sacubitril-Valsartan

Synonyms

Sacubitril valsartan sodium hydrate, Sacubitril mixture with valsartan, Wb8ft61183, Lcz 696, Sacubitril valsartan sodium hydrate (jan), Sacubitril valsartan sodium hydrate [jan]

Cas Number

936623-90-4

Unique Ingredient Identifier (UNII)

WB8FT61183

About Sacubitril-Valsartan

Sacubitril/Valsartan is a combination of sacubitril and valsartan with natriuretic and anti-hypertensive properties. Upon administration, sacubitril is metabolized by esterases to its active metabolite, LBQ657 (sacubitrilat), which inhibits neprilysin, a neutral endopeptidase that cleaves natriuretic peptides such as atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and c-type natriuretic peptide (CNP), as well as certain vasoconstricting peptides including as angiotensin I and II, and endothelin-1. Inhibition of neprilysin leads to increased concentrations of endogenous natriuretic peptides, which function to activate downstream receptors that promote vasodilation, natriuresis and diuresis, while simultaneously increasing the concentration of vasoconstricting peptides such as angiotensin II. Co-administration with valsartan, an angiotensin II receptor blocker, prevents the vasoconstrictive effects of neprilysin inhibition and promotes a decrease in vascular resistance and blood pressure.

Sacubitril-Valsartan Manufacturers

A Sacubitril-Valsartan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sacubitril-Valsartan, including repackagers and relabelers. The FDA regulates Sacubitril-Valsartan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sacubitril-Valsartan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sacubitril-Valsartan manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sacubitril-Valsartan Suppliers

A Sacubitril-Valsartan supplier is an individual or a company that provides Sacubitril-Valsartan active pharmaceutical ingredient (API) or Sacubitril-Valsartan finished formulations upon request. The Sacubitril-Valsartan suppliers may include Sacubitril-Valsartan API manufacturers, exporters, distributors and traders.

click here to find a list of Sacubitril-Valsartan suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sacubitril-Valsartan Manufacturers | Traders | Suppliers

We have 40 companies offering Sacubitril-Valsartan

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

List of all Manufacturers, Suppliers & Exporters of Sacubitril-Valsartan API listed on PharmaCompass with details of regulatory filings