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    Momelotinib dihydrochloride monohydrate

    ACTIVE PHARMA INGREDIENTS

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    Biophore India Pharmaceuticals Pvt...

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    Cambrex Corporation

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    NDC Package Code : 12651-123

    Start Marketing Date : 2023-02-08

    End Marketing Date : 2026-12-31

    Dosage Form (Strength) : POWDER (1kg/kg)

    Marketing Category : BULK INGREDIENT

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    Jinan Tantu Chemicals

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    Looking for 1841094-17-4 / Momelotinib Hydrochloride API manufacturers, exporters & distributors?

    Momelotinib Hydrochloride manufacturers, exporters & distributors 1

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    PharmaCompass offers a list of Momelotinib Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Momelotinib Hydrochloride manufacturer or Momelotinib Hydrochloride supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Momelotinib Hydrochloride manufacturer or Momelotinib Hydrochloride supplier.

    API | Excipient name

    Momelotinib Hydrochloride

    Synonyms

    Momelotinib dihydrochloride monohydrate, Ldx8893l5d, Cyt-387 dihydrochloride monohydrate, Cyt-11387 dihydrochloride monohydrate, Momelotinib hydrochloride hydrate (jan), Momelotinib hydrochloride hydrate [jan]

    Cas Number

    1841094-17-4

    Unique Ingredient Identifier (UNII)

    LDX8893L5D

    About Momelotinib Hydrochloride

    Momelotinib Dihydrochloride Monohydrate is the monohydrate dihydrochloride salt form of momelotinib, an orally bioavailable small molecule inhibitor of wild-type (WT) Janus kinases 1 and 2 (JAK1/2), the JAK2 mutant form JAK2V617F, and activin A receptor type 1 (ACVR1; activin receptor like kinase 2; ALK2), with antineoplastic activity. Upon oral administration, momelotinib competes with JAK1/2 for ATP binding, which results in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and leads to the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. In addition, the inhibition of ALK2 prevents liver hepcidin formation, increases iron availability and increases red blood cell (RBC) production. JAK2 is the most common mutated gene in bcr-abl-negative myeloproliferative disorders; the JAK2V617F gain-of-function mutation involves a valine-to-phenylalanine modification at position 617. The JAK-STAT signaling pathway is a major mediator of cytokine activity and is often dysregulated in a variety of tumor cell types.

    Momelotinib dihydrochloride monohydrate Manufacturers

    A Momelotinib dihydrochloride monohydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Momelotinib dihydrochloride monohydrate, including repackagers and relabelers. The FDA regulates Momelotinib dihydrochloride monohydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Momelotinib dihydrochloride monohydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Momelotinib dihydrochloride monohydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

    Momelotinib dihydrochloride monohydrate Suppliers

    A Momelotinib dihydrochloride monohydrate supplier is an individual or a company that provides Momelotinib dihydrochloride monohydrate active pharmaceutical ingredient (API) or Momelotinib dihydrochloride monohydrate finished formulations upon request. The Momelotinib dihydrochloride monohydrate suppliers may include Momelotinib dihydrochloride monohydrate API manufacturers, exporters, distributors and traders.

    click here to find a list of Momelotinib dihydrochloride monohydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

    Momelotinib dihydrochloride monohydrate Manufacturers | Traders | Suppliers

    Momelotinib dihydrochloride monohydrate Manufacturers, Traders, Suppliers 1
    88

    We have 4 companies offering Momelotinib dihydrochloride monohydrate

    Get in contact with the supplier of your choice:

    1. Biophore India Pharmaceuticals Pvt Ltd
    2. Cambrex Corporation
    3. Daishang Pharmchem Group
    4. Jinan Tantu Chemicals
    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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