Momelotinib dihydrochloride monohydrate API Manufacturers | Suppliers | Exporters

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Biophore India Pharmaceuticals Pvt ...

India

CPhI China

Exhibiting

Biophore is a research-driven global pharmaceutical company focused on niche APIs for the generic industry.

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India

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Momelotinib Hydrochloride

About the Company : Biophore, founded in 2007, develops and manufactures niche and complex pharmaceutical products. With USFDA- and EU-approved API facilities, a dedicated intermediates site and an R&...

Biophore, founded in 2007, develops and manufactures niche and complex pharmaceutical products. With USFDA- and EU-approved API facilities, a dedicated intermediates site and an R&D center of 400 scientists, the company is a leading global API player. Biophore ranks among the top US DMF filers, holds 150+ patents and maintains a strong compliance record with major regulatory agencies. Note: None of the products will be supplied to countries in which this could be in conflict with existing patents. Further, any products under patent will be offered for R&D purposes only. However, the final responsibility lies with the buyer.

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02

Daishang Pharmchem Group

China

PCC

Not Confirmed

03

Jinan Tantu Chemicals

China

PCC

Not Confirmed

Looking for 1841094-17-4 / Momelotinib Hydrochloride API manufacturers, exporters & distributors?

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API | Excipient name

Momelotinib Hydrochloride

Synonyms

Momelotinib dihydrochloride monohydrate, Ldx8893l5d, Cyt-387 dihydrochloride monohydrate, Cyt-11387 dihydrochloride monohydrate, Momelotinib hydrochloride hydrate (jan), Momelotinib hydrochloride hydrate [jan]

Cas Number

1841094-17-4

Unique Ingredient Identifier (UNII)

LDX8893L5D

About Momelotinib Hydrochloride

Momelotinib Dihydrochloride Monohydrate is the monohydrate dihydrochloride salt form of momelotinib, an orally bioavailable small molecule inhibitor of wild-type (WT) Janus kinases 1 and 2 (JAK1/2), the JAK2 mutant form JAK2V617F, and activin A receptor type 1 (ACVR1; activin receptor like kinase 2; ALK2), with antineoplastic activity. Upon oral administration, momelotinib competes with JAK1/2 for ATP binding, which results in inhibition of JAK1/2 activation, inhibition of the JAK-STAT signaling pathway, and leads to the induction of apoptosis and a reduction of tumor cell proliferation in JAK1/2-expressing tumor cells. In addition, the inhibition of ALK2 prevents liver hepcidin formation, increases iron availability and increases red blood cell (RBC) production. JAK2 is the most common mutated gene in bcr-abl-negative myeloproliferative disorders; the JAK2V617F gain-of-function mutation involves a valine-to-phenylalanine modification at position 617. The JAK-STAT signaling pathway is a major mediator of cytokine activity and is often dysregulated in a variety of tumor cell types.

Momelotinib dihydrochloride monohydrate Manufacturers

A Momelotinib dihydrochloride monohydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Momelotinib dihydrochloride monohydrate, including repackagers and relabelers. The FDA regulates Momelotinib dihydrochloride monohydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Momelotinib dihydrochloride monohydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Momelotinib dihydrochloride monohydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.

Momelotinib dihydrochloride monohydrate Suppliers

A Momelotinib dihydrochloride monohydrate supplier is an individual or a company that provides Momelotinib dihydrochloride monohydrate active pharmaceutical ingredient (API) or Momelotinib dihydrochloride monohydrate finished formulations upon request. The Momelotinib dihydrochloride monohydrate suppliers may include Momelotinib dihydrochloride monohydrate API manufacturers, exporters, distributors and traders.

click here to find a list of Momelotinib dihydrochloride monohydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.

Momelotinib dihydrochloride monohydrate Manufacturers | Traders | Suppliers

We have 3 companies offering Momelotinib dihydrochloride monohydrate

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Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.