Synopsis
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1. 38748-32-2
2. Nsc-163062
3. 19ald1s53j
4. Dtxsid5041144
5. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
6. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo(11.7.0.02,4.02,9.05,7.09,11.014,18)icos-14(18)-en-17-one
7. Refchem:192024
8. Dtxcid3021144
9. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo(11.7.0.0^(2,4).0^(2,9).0^(5,7).0^(9,11).0^(14,18))icos-14(18)-en-17-one
10. 683-214-2
11. Pg490
12. Triptolid
13. Mfcd00210565
14. Nsc 163062
15. Chebi:9747
16. Chembl463763
17. Pg-490
18. (5bs,6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2h)-one
19. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-6-hydroxy-8b-methyl-6a-(propan-2-yl)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3h)-one
20. (6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2h)-one.
21. Smr000466307
22. Unii-19ald1s53j
23. Triptolide?
24. Triptolide, 1
25. Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-
26. Pg 490
27. Cpd000466307
28. Triptolide [mi]
29. Triptolide [who-dd]
30. Bspbio_001595
31. Kbiogr_000315
32. Kbioss_000315
33. Mls000759410
34. Mls001424107
35. Mls006010844
36. Schembl413634
37. Orb1306199
38. Ex-a7744a
39. Kbio2_000315
40. Kbio2_002883
41. Kbio2_005451
42. Kbio3_000629
43. Kbio3_000630
44. Bio2_000315
45. Bio2_000795
46. Glxc-06921
47. Hms1361p17
48. Hms1791p17
49. Hms1989p17
50. Hms2051n13
51. Hms3402p17
52. Msk40281
53. Bdbm50241049
54. Nsc163062
55. Nsc839303
56. S3604
57. Akos022168197
58. Ccg-100957
59. Cs-0286
60. Db12025
61. Ft28581
62. Nc00207
63. Nsc-839303
64. Idi1_034065
65. Ncgc00163411-01
66. Ncgc00163411-02
67. Ncgc00163411-03
68. Ncgc00163411-07
69. Bp-25386
70. Bs-16697
71. Hy-32735
72. Nci60_001223
73. Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-
74. Ns00018025
75. T2899
76. C09204
77. Ab00639938-06
78. Ab00639938-08
79. 748t322
80. F557653
81. Q906351
82. Brd-k39484304-001-02-5
83. Brd-k39484304-001-06-6
84. Brd-k39484304-001-16-5
85. Triptolide, Tripterygium Wilfordii - Cas 38748-32-2
86. (1s,2s,4s,5s,7r,8r,9s,11s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
87. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
88. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-6a-isopropyl-8b-methyltrisoxireno(6,7:8a,9:4b,5)phenanthro(1,2-c)furan-1(3h)-one
89. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one
90. (5bs,6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-2,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(1h)-one
91. Pg 490; (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-6-hydroxy-6a-isopropyl-8b-methyl-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a
92. Trisoxireno[4b,7:8a,9]phenanthro[1,2-c]furan-(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3br-(3b.alpha.,4a.alpha.,5as*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8as*,8b.beta.)]-
93. Trisoxireno[4b,7:8a,9]phenanthro[1,2-c]furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3br-(3b.alpha.,4a.alpha.,5as*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8as*,8b.beta.)]-
| Molecular Weight | 360.4 g/mol |
|---|---|
| Molecular Formula | C20H24O6 |
| XLogP3 | 0.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 84.1 |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 819 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Antispermatogenic Agents
Agents, either mechanical or chemical, which destroy spermatozoa in the male genitalia and block spermatogenesis.
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Antineoplastic Agents, Alkylating
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
ABOUT THIS PAGE
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PharmaCompass offers a list of Triptolide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Triptolide manufacturer or Triptolide supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Triptolide manufacturer or Triptolide supplier.
A Triptolide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Triptolide, including repackagers and relabelers. The FDA regulates Triptolide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Triptolide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Triptolide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PhamaCompass.
A Triptolide supplier is an individual or a company that provides Triptolide active pharmaceutical ingredient (API) or Triptolide finished formulations upon request. The Triptolide suppliers may include Triptolide API manufacturers, exporters, distributors and traders.
click here to find a list of Triptolide suppliers with USDMF, JDMF, KDMF, CEP, GMP, and COA related information on PharmaCompass.
Triptolide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Triptolide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, and more, enabling you to easily find the right Triptolide GMP manufacturer or Triptolide GMP API supplier for your needs.
A Triptolide CoA (Certificate of Analysis) is a formal document that attests to Triptolide's compliance with Triptolide specifications and serves as a tool for batch-level quality control.
Triptolide CoA mostly includes findings from lab analyses of a specific batch. For each Triptolide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Triptolide may be tested according to a variety of international standards, such as European Pharmacopoeia (Triptolide EP), Triptolide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Triptolide USP).
