1. 38748-32-2
2. Nsc-163062
3. 19ald1s53j
4. Dtxsid5041144
5. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
6. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo(11.7.0.02,4.02,9.05,7.09,11.014,18)icos-14(18)-en-17-one
7. Refchem:192024
8. Dtxcid3021144
9. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-1-methyl-7-(propan-2-yl)-3,6,10,16-tetraoxaheptacyclo(11.7.0.0^(2,4).0^(2,9).0^(5,7).0^(9,11).0^(14,18))icos-14(18)-en-17-one
10. 683-214-2
11. Pg490
12. Triptolid
13. Mfcd00210565
14. Nsc 163062
15. Chebi:9747
16. Chembl463763
17. Pg-490
18. (5bs,6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2h)-one
19. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-6-hydroxy-8b-methyl-6a-(propan-2-yl)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3h)-one
20. (6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(2h)-one.
21. Smr000466307
22. Unii-19ald1s53j
23. Triptolide?
24. Triptolide, 1
25. Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-
26. Pg 490
27. Cpd000466307
28. Triptolide [mi]
29. Triptolide [who-dd]
30. Bspbio_001595
31. Kbiogr_000315
32. Kbioss_000315
33. Mls000759410
34. Mls001424107
35. Mls006010844
36. Schembl413634
37. Orb1306199
38. Ex-a7744a
39. Kbio2_000315
40. Kbio2_002883
41. Kbio2_005451
42. Kbio3_000629
43. Kbio3_000630
44. Bio2_000315
45. Bio2_000795
46. Glxc-06921
47. Hms1361p17
48. Hms1791p17
49. Hms1989p17
50. Hms2051n13
51. Hms3402p17
52. Msk40281
53. Bdbm50241049
54. Nsc163062
55. Nsc839303
56. S3604
57. Akos022168197
58. Ccg-100957
59. Cs-0286
60. Db12025
61. Ft28581
62. Nc00207
63. Nsc-839303
64. Idi1_034065
65. Ncgc00163411-01
66. Ncgc00163411-02
67. Ncgc00163411-03
68. Ncgc00163411-07
69. Bp-25386
70. Bs-16697
71. Hy-32735
72. Nci60_001223
73. Trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-
74. Ns00018025
75. T2899
76. C09204
77. Ab00639938-06
78. Ab00639938-08
79. 748t322
80. F557653
81. Q906351
82. Brd-k39484304-001-02-5
83. Brd-k39484304-001-06-6
84. Brd-k39484304-001-16-5
85. Triptolide, Tripterygium Wilfordii - Cas 38748-32-2
86. (1s,2s,4s,5s,7r,8r,9s,11s)-8-hydroxy-1-methyl-7-propan-2-yl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
87. (1s,2s,4s,5s,7r,8r,9s,11s,13s)-8-hydroxy-7-isopropyl-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
88. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-6a-isopropyl-8b-methyltrisoxireno(6,7:8a,9:4b,5)phenanthro(1,2-c)furan-1(3h)-one
89. (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno(4b,5:6,7:8a,9)phenanthro(1,2-c)furan-1(3h)-one
90. (5bs,6as,7as,8r,8ar,9as,9bs,10as,10bs)-8-hydroxy-8a-isopropyl-10b-methyl-2,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5;2'',3'':6,7;2''',3''':8a,9]phenanthro[1,2-c]furan-3(1h)-one
91. Pg 490; (3bs,4as,5as,6r,6ar,7as,7bs,8as,8bs)-6-hydroxy-6a-isopropyl-8b-methyl-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydrotrisoxireno[6,7:8a
92. Trisoxireno[4b,7:8a,9]phenanthro[1,2-c]furan-(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3br-(3b.alpha.,4a.alpha.,5as*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8as*,8b.beta.)]-
93. Trisoxireno[4b,7:8a,9]phenanthro[1,2-c]furan-1(3h)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, [3br-(3b.alpha.,4a.alpha.,5as*,6.beta.,6a.beta.,7a.beta.,7b.alpha.,8as*,8b.beta.)]-
| Molecular Weight | 360.4 g/mol |
|---|---|
| Molecular Formula | C20H24O6 |
| XLogP3 | 0.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | Da |
| Monoisotopic Mass | Da |
| Topological Polar Surface Area | 84.1 |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 819 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Antispermatogenic Agents
Agents, either mechanical or chemical, which destroy spermatozoa in the male genitalia and block spermatogenesis.
Immunosuppressive Agents
Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Antineoplastic Agents, Alkylating
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)
