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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
TH1902 (sudocetaxel zendusortide) is an investigational, first-in-class peptide-drug conjugate (PDC) that targets the sortilin (SORT1) receptor and expedites the internalization and delivery of a cytotoxic payload directly into cancer cells.
TH1902 (sudocetaxel zendusortide) is an investigational, first-in-class peptide-drug conjugate (PDC) that targets the sortilin (SORT1) receptor and expedites the internalization and delivery of a cytotoxic payload directly into cancer cells.
RP-6306 (lunresertib) is a PKMYT1 inhibitor currently in Phase 1 clinical development a potential leading ATR inhibitor currently in Phase 1/2 clinical development and partnered with Roche.
TH1902 (sudocetaxel zendusortide)sudocetaxel zendusortide, an investigational, first-in-class peptide-drug conjugate (PDC) that targets the sortilin (SORT1) receptor and expedites the internalization and delivery of a cytotoxic payload directly into cancer cells.
ESSA will conduct a Phase 1 trial evaluating the safety, pharmacokinetics, drug-drug interactions, and preliminary anti-tumor activity of EPI-7386 when administered in combination with either apalutamide or abiraterone acetate plus prednisone in patients with prostate cancer.
FPI-2059 is a small molecule targeted alpha therapy designed to deliver actinium-225 to tumor sites expressing neurotensin receptor 1 (NTSR1), a protein that is overexpressed in gastrointestinal, prostate, pancreatic ductal adenocarcinoma and multiple other cancers.
TH1902 is a proprietary PDC, linked to docetaxel, a cytotoxic agent. The U.S. FDA recently granted fast track designation to TH1902 for the treatment of all advanced solid tumors expressing sortilin that are refractory to standard therapy.
TH1902 is currently Theratechnologies’ lead investigational PDC candidate for the treatment of cancer derived from its SORT1+ Technology™. It is the Company’s proprietary peptide linked to docetaxel – a commonly used cytotoxic agent used to treat many cancers.
EPI-7386 is an investigational, highly-selective, oral, small molecule inhibitor of the N-terminal domain of the androgen receptor. EPI-7386 is being studied in men with castration-resistant prostate cancer ("CRPC") whose tumors have progressed on standard-of-care therapies.
TH1902 is a PDC, where Theratechnologies’ proprietary peptide is linked to docetaxel, a well-established and well-characterized cytotoxic agent. The U.S. FDA recently granted fast track designation to TH1902 to be developed as a single agent for the treatment of solid tumors.