
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

NextPoint Therapeutics Doses First Patient in Phase 1a/b Trial of NPX887
Details : NPX887 is a fully human monoclonal antibody targeting HHLA2 (B7-H7), under evaluation for various solid tumors, including non-small cell lung cancer and renal cell carcinoma.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 20, 2024

NextPoint Therapeutics Closes Series B Financing Extension Led By Catalio Capital
Details : Funds will support the development of NPX267, targeting metastatic solid tumors, including EGFR-mutant non-small cell lung cancer and HHLA2-expressing metastatic neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
February 14, 2024

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2
Details : NPX887 is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
February 05, 2024

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Lead Product(s) : NPX887
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NextPoint investigational product NPX887 is a fully human monoclonal antibody targeting HHLA2 (B7-H7). Currently evaluating under the IND enabling stage for the treatment of solid tumors known to express HHLA2, a tumor antigen strongly upregulated in man...
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
December 07, 2023
Lead Product(s) : NPX887
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Details : NPX267 is a first-in-class monoclonal antibody targeting KIR3DL3, the inhibitory receptor for the HHLA2 pathway (B7-H7), and is designed to prevent immune escape in solid tumors.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 17, 2023

A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7
Details : NPX267 is a Other Large Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Neoplasms.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 24, 2023

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Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Undisclosed
Sponsor : Leaps by Bayer
Deal Size : $80.0 million
Deal Type : Series B Financing
Details : The financing will be used to advance NextPoint’s two lead precision immuno-oncology programs into the clinic, both targeting the newly discovered HHLA2 pathway to activate anti-tumor immune responses.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
January 10, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Sponsor : Leaps by Bayer
Deal Size : $80.0 million
Deal Type : Series B Financing
