Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
AstraZeneca To Acquire Neogene Therapeutics, Accelerating Ambition in Oncology Cell Therapy
Details : With a shared goal of bringing cell therapies to patients with solid tumours, Neogene’s expertise in TCR-T discovery, development and manufacturing will strengthen AstraZeneca’s ambition to transform outcomes for patients.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $200.0 million
November 29, 2022
Lead Product(s) : NT-125
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NT-125, designed to contain up to five distinct neoantigen-specific TCRs per patient in single cell product of highly functional engineered T cells, allowing multiple neoantigens by HLA molecules targeted with goal to create a more impactful TCR therapy ...
Product Name : NT-125
Product Type : Cell and Gene therapy
Upfront Cash : Inapplicable
October 05, 2022
Lead Product(s) : NT-125
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Acquisition of Neogene Therapeutics Completed
Details : Acquisition will provide access to next-generation T-cell receptor therapies with promising potential for targeting solid tumours to AstraZeneca. TCR-based Therapies can recognise intracellular targets, including cancer-specific mutations.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $320.0 million
January 16, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : EcoR1 Capital
Deal Size : $110.0 million
Deal Type : Series A Financing
Details : Neogene’s proprietary technology platform identifies specific T cell receptor (TCR) genes from routine tumor samples using state-of-the-art synthetic biology tools.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 14, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : EcoR1 Capital
Deal Size : $110.0 million
Deal Type : Series A Financing