[{"orgOrder":0,"company":"Hinge Bio","sponsor":"Ridgeback Capital","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2025","type":"Series A Financing","leadProduct":"HB2198","moa":"CD19\/20","graph1":"Immunology","graph2":"IND Enabling","graph3":"Hinge Bio","amount2":0.029999999999999999,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.029999999999999999,"dosageForm":"Undisclosed","sponsorNew":"Hinge Bio \/ Ridgeback Capital","highestDevelopmentStatusID":"5","companyTruncated":"Hinge Bio \/ Ridgeback Capital"},{"orgOrder":0,"company":"Hinge Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Discovery","graph3":"Hinge Bio","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hinge Bio \/ Undisclosed","highestDevelopmentStatusID":"2","companyTruncated":"Hinge Bio \/ Undisclosed"},{"orgOrder":0,"company":"Hinge Bio","sponsor":"KYORIN PHARMACEUTICAL CO LTD","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2025","type":"Collaboration","leadProduct":"HB2198","moa":"CD19\/20","graph1":"Immunology","graph2":"IND Enabling","graph3":"Hinge Bio","amount2":0.11,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0.11,"dosageForm":"Undisclosed","sponsorNew":"Hinge Bio \/ KYORIN PHARMACEUTICAL CO LTD","highestDevelopmentStatusID":"5","companyTruncated":"Hinge Bio \/ KYORIN PHARMACEUTICAL CO LTD"},{"orgOrder":0,"company":"Hinge Bio","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2025","type":"Inapplicable","leadProduct":"HB2198","moa":"CD19\/20","graph1":"Immunology","graph2":"IND Enabling","graph3":"Hinge Bio","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hinge Bio \/ Undisclosed","highestDevelopmentStatusID":"5","companyTruncated":"Hinge Bio \/ Undisclosed"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : HB2198, an unconjugated antibody targeting CD19/20, shows promise in treating Systemic Lupus Erythematosus (SLE).

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          October 13, 2025

                          Lead Product(s) : HB2198

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The agreement aims for the development of Hinge’s multispecific antibody-based therapeutic HB2198 in Japan for Systemic Lupus Erythematosus.

                          Product Name : HB2198

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : $10.0 million

                          September 30, 2025

                          Lead Product(s) : HB2198

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : KYORIN PHARMACEUTICAL CO LTD

                          Deal Size : $105.0 million

                          Deal Type : Collaboration

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                          03

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : The proceeds will support the Company in advancing its lead product candidate, HB2198, into a clinical trial in patients living with Systemic Lupus Erythematosus.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Undisclosed

                          January 15, 2025

                          Lead Product(s) : HB2198

                          Therapeutic Area : Immunology

                          Highest Development Status : Preclinical

                          Sponsor : Ridgeback Capital

                          Deal Size : $30.0 million

                          Deal Type : Series A Financing

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                          04

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : GEM-DIMER™ molecule may improve the therapeutic benefit by incorporating antibody and other protein domains that direct tumor targeting, T/NK/macrophage effector cell engagement and effector cell activation, as well as to localize activity of tumor mic...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          January 18, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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