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															DEALS // DEV.
 
															Country
 
															 
															Therapeutic Area
 
															Study Phase
 
															Deal Type
 
															Product Type
 
															Dosage Form
 
															Lead Product
 
															Target

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Lead Product(s) : HB2198
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Hinge Bio's HB2198 FDA Cleared for Lupus Erythematosus and Nephritis
Details : HB2198, an unconjugated antibody targeting CD19/20, shows promise in treating Systemic Lupus Erythematosus (SLE).
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
October 13, 2025
Lead Product(s) : HB2198
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : HB2198
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : KYORIN PHARMACEUTICAL CO LTD
Deal Size : $105.0 million
Deal Type : Collaboration
Hinge Bio Announces License and Collaboration with Kyorin Pharmaceutical
Details : The agreement aims for the development of Hinge’s multispecific antibody-based therapeutic HB2198 in Japan for Systemic Lupus Erythematosus.
Product Name : HB2198
Product Type : Antibody, Unconjugated
Upfront Cash : $10.0 million
September 30, 2025
Lead Product(s) : HB2198
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : KYORIN PHARMACEUTICAL CO LTD
Deal Size : $105.0 million
Deal Type : Collaboration

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Lead Product(s) : HB2198
Therapeutic Area : Immunology
Study Phase : Preclinical
Sponsor : Ridgeback Capital
Deal Size : $30.0 million
Deal Type : Series A Financing
Hinge Bio Secures $30M Series A’ for GEM-DIMER Platform Therapies
Details : The proceeds will support the Company in advancing its lead product candidate, HB2198, into a clinical trial in patients living with Systemic Lupus Erythematosus.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Undisclosed
January 15, 2025
Lead Product(s) : HB2198
Therapeutic Area : Immunology
Highest Development Status : Preclinical
Sponsor : Ridgeback Capital
Deal Size : $30.0 million
Deal Type : Series A Financing

Hinge Bio Expands Senior Management Team to Drive GEM-DIMER™ Programs to Clinical Development
Details : GEM-DIMER™ molecule may improve the therapeutic benefit by incorporating antibody and other protein domains that direct tumor targeting, T/NK/macrophage effector cell engagement and effector cell activation, as well as to localize activity of tumor mic...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 18, 2023

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