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Receives Orphan Drug Designation for Immunogene Therapy for Treatment of SCLC","therapeuticArea":"Oncology","highestDevelopmentStatus":"Phase I\/ Phase II","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"September 2023","url1":"","url2":"","graph1":"Oncology","graph2":"Phase I\/ Phase II"},{"orgOrder":0,"company":"Genprex","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Genprex Collaborators Publish Positive Preclinical Data with NPRL2 Gene Therapy Utilizing Oncoprex\u00ae Delivery System","therapeuticArea":"Oncology","highestDevelopmentStatus":"Preclinical","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"April 2024","url1":"","url2":"","graph1":"Oncology","graph2":"Preclinical"}]
Find Clinical Drug Pipeline Developments & Deals by Genprex
Reqorsa Immunogene Therapy (quaratusugene ozeplasmid) uses Genprex’s unique, proprietary ONCOPREX nanoparticle delivery system and combination with Tecentriq for the treatment of small cell lung cancer.
Lead Product(s):
Quaratusugene Ozeplasmid,Atezolizumab
Reqorsa Immunogene Therapy (quaratusugene ozeplasmid) uses Genprex’s unique, proprietary ONCOPREX nanoparticle delivery system and combination with Tecentriq in extensive-stage small cell lung cancer.
Lead Product(s):
Quaratusugene Ozeplasmid,Atezolizumab
Under the agreement, Genprex gains a worldwide, exclusive license to a patent application and related technology and a worldwide, non-exclusive license to use certain related know-how, all related to a gene therapy, GPX-002, for both Type 1 and Type 2 diabetes.
Reqorsa Immunogene Therapy (quaratusugene ozeplasmid) uses Genprex’s unique, proprietary ONCOPREX Nanoparticle Delivery System and Combination with Tagrisso® in Advanced Non-Small Cell Lung Cancer
Lead Product(s):
Quaratusugene Ozeplasmid,Atezolizumab
University of Pittsburgh grants Genprex a preclinical technology that transforms macrophages, complementary to the GPX-002 diabetes technology. Novel infusion process uses an endoscope and an AAV vector with a glucagon promoter to deliver the Pdx1 + MafA genes to the pancreas.
The diabetes gene therapy, GPX-002, is comprised of a novel infusion process that uses an endoscope and an adeno-associated virus (AAV) vector to deliver Pdx1 and MafA genes to the pancreas.
Diabetic mice studies have shown that GPX-002, a gene therapy for diabetes, restored normal blood glucose levels for an extended period of time, which could translate to decades in humans.
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