Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Circle Pharma Doses First Patients in Trial for Oral Cyclin A/B Inhibitor CID-078
Details : CID-078 is a cyclin A/B RxL inhibitor. The trial will evaluate it in patients with advanced solid tumors with elevated E2F transcription factor activity, such as lung cancer and breast cancer.
Product Name : CID-078
Product Type : Peptide
Upfront Cash : Inapplicable
October 15, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $607.0 million
Deal Type : Collaboration
Boehringer Ingelheim and Circle Pharma Announce Precision Cancer Treatment Pact
Details : The collaboration aims to develop a first-in-class cyclin inhibitor that can halt the growth of cancer cells potentially offering hope to those living with hard-to-treat cancers.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 10, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Boehringer Ingelheim GmbH
Deal Size : $607.0 million
Deal Type : Collaboration
Circle Pharma Closes $90 Million Series D to Advance Oral Macrocycle Therapies
Details : The financing aims to fund the clinical development of CID-078, which is being evaluated in the early-stage clinical trial studies for the treatment of Advanced Solid Tumor.
Product Name : CID-078
Product Type : Peptide
Upfront Cash : Undisclosed
March 09, 2024
Lead Product(s) : CID-078
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Circle Pharma Files IND for First-in-Class Oral Cyclin A/B RxL Inhibitor for Solid Tumors
Details : CID-078 is an orally bioavailable macrocycle and the first of its kind cyclin A/B RxL inhibitor, developed using the company’s proprietary MXMO platform for the treatment of multiple solid tumors.
Product Name : CID-078
Product Type : Peptide
Upfront Cash : Inapplicable
January 07, 2024
Lead Product(s) : CID-078
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CID-078
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CID-078 is a small molecule orally bioavailable macrocycle with dual cyclin A and B inhibitory activity that drives synthetic lethality in multiple tumor types.
Product Name : CID-078
Product Type : Peptide
Upfront Cash : Inapplicable
July 19, 2023
Lead Product(s) : CID-078
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Circle Pharma Raises $66 Million in Series C Financing
Details : Proceeds from the financing will be used to advance the Company’s wholly owned cyclin-targeted programs towards the clinic, with potential applications in Rb-dysregulated cancers such as small cell lung cancer and cyclin E dependent malignancies, inclu...
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
June 16, 2021