[{"orgOrder":0,"company":"Circle Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Inapplicable","leadProduct":"CID-078","moa":"Cyclin A\/Cyclin B RxL","graph1":"Oncology","graph2":"Preclinical","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Circle Pharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Circle Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Circle Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Inapplicable","leadProduct":"CID-078","moa":"Cyclin A\/Cyclin B RxL","graph1":"Oncology","graph2":"IND Enabling","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Circle Pharma \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Circle Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Circle Pharma","sponsor":"Boehringer Ingelheim GmbH","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Cyclin","graph1":"Oncology","graph2":"Preclinical","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Circle Pharma \/ Boehringer Ingelheim GmbH","highestDevelopmentStatusID":"4","companyTruncated":"Circle Pharma \/ Boehringer Ingelheim GmbH"},{"orgOrder":0,"company":"Circle Pharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Inapplicable","leadProduct":"CID-078","moa":"Cyclin A\/Cyclin B RxL","graph1":"Oncology","graph2":"Phase I","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Circle Pharma \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Circle Pharma \/ Inapplicable"},{"orgOrder":0,"company":"Circle Pharma","sponsor":"The Column Group","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Peptide","year":"2024","type":"Series D Financing","leadProduct":"CID-078","moa":"Cyclin A\/Cyclin B RxL","graph1":"Oncology","graph2":"Phase I","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Circle Pharma \/ The Column Group","highestDevelopmentStatusID":"6","companyTruncated":"Circle Pharma \/ The Column Group"},{"orgOrder":0,"company":"Circle Pharma","sponsor":"The Column Group And Nextech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Series C Financing","leadProduct":"Undisclosed","moa":"Cyclin A","graph1":"Oncology","graph2":"Discovery","graph3":"Circle Pharma","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Circle Pharma \/ The Column Group And Nextech","highestDevelopmentStatusID":"2","companyTruncated":"Circle Pharma \/ The Column Group And Nextech"}]

Find Clinical Drug Pipeline Developments & Deals by Circle Pharma

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                          Top Deals by Deal Size (USD bn)

                          01

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : CID-078 is a cyclin A/B RxL inhibitor. The trial will evaluate it in patients with advanced solid tumors with elevated E2F transcription factor activity, such as lung cancer and breast cancer.

                          Product Name : CID-078

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          October 15, 2024

                          Lead Product(s) : CID-078

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : The collaboration aims to develop a first-in-class cyclin inhibitor that can halt the growth of cancer cells potentially offering hope to those living with hard-to-treat cancers.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          September 10, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : $607.0 million

                          Deal Type : Collaboration

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                          03

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : The financing aims to fund the clinical development of CID-078, which is being evaluated in the early-stage clinical trial studies for the treatment of Advanced Solid Tumor.

                          Product Name : CID-078

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          March 09, 2024

                          Lead Product(s) : CID-078

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : The Column Group

                          Deal Size : $90.0 million

                          Deal Type : Series D Financing

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                          04

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : CID-078 is an orally bioavailable macrocycle and the first of its kind cyclin A/B RxL inhibitor, developed using the company’s proprietary MXMO platform for the treatment of multiple solid tumors.

                          Product Name : CID-078

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          January 07, 2024

                          Lead Product(s) : CID-078

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : CID-078 is a small molecule orally bioavailable macrocycle with dual cyclin A and B inhibitory activity that drives synthetic lethality in multiple tumor types.

                          Product Name : CID-078

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          July 19, 2023

                          Lead Product(s) : CID-078

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          RDD 2025
                          Not Confirmed
                          RDD 2025
                          Not Confirmed

                          Details : Proceeds from the financing will be used to advance the Company’s wholly owned cyclin-targeted programs towards the clinic, with potential applications in Rb-dysregulated cancers such as small cell lung cancer and cyclin E dependent malignancies, inclu...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          June 16, 2021

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : The Column Group And Nextech

                          Deal Size : $66.0 million

                          Deal Type : Series C Financing

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