Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Study of ASN51 in Adults With Early Alzheimer's Disease
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 06, 2024
Asceneuron raises $100M series C for ph. 2 Alzheimer's trial
Details : The Funds will be used to progress lead asset ASN51, an oral small molecule OGA inhibitor, into Phase 2 clinical development for the treatment of Alzheimer’s disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 16, 2024
Lead Product(s) : ASN51
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Hammersmith Medicines Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 30, 2024
Lead Product(s) : ASN51
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Hammersmith Medicines Research
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Fluvoxamine
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 30, 2024
Lead Product(s) : Fluvoxamine
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ASN90
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Ferrer Internacional
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Under the licensing agreement, Ferrer obtains the exclusive worldwide rights to develop and commercialize ASN90, an O-GlcNAcase inhibitor, in progressive supranuclear palsy (PSP), an orphan, tau-related disease with a high unmet medical need.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
February 22, 2023
Lead Product(s) : ASN90
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Ferrer Internacional
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : ASN51
Therapeutic Area : Undisclosed
Study Phase : Phase I
Sponsor : Hammersmith Medicines Research | Invicro
Deal Size : Inapplicable
Deal Type : Inapplicable
PET Study of Repeated ASN51 in Healthy Volunteers
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 13, 2023
Lead Product(s) : ASN51
Therapeutic Area : Undisclosed
Highest Development Status : Phase I
Sponsor : Hammersmith Medicines Research | Invicro
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ASN51
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : Undisclosed
Deal Type : Funding
Details : The grant will fund a preclinical proof-of-concept study to assess the disease-modifying properties of Asceneuron’s OGA inhibitor ASN51 in a preclinical model of inherited PD.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
March 05, 2022
Lead Product(s) : ASN51
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Michael J. Fox Foundation for Parkinson’s Research
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : ASN90
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Findings published demonstrated increased survival in preclinical model of Alzheimer's disease after administration of clinical molecule ASN90, an O–GlcNAcase inhibitor, as well as significant motor impairment and astrogliosis effect in a Parkinson's m...
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 04, 2022
Lead Product(s) : ASN90
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Asceneuron to Provide Update on O-GlcNAcase Pipeline at Upcoming Conferences
Details : ASN120290, an O-GlcNAcase inhibitor, is being developed for the orphan tauopathic disease, progressive supranuclear palsy (PSP), and was granted Orphan Drug Designation by the US FDA for the treatment of Progressive Supranuclear Palsy (PSP).
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
September 30, 2021
Details : Undisclosed
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 18, 2021