
Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target

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Lead Product(s) : Bryoid
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : National Institute on Aging
Deal Size : Undisclosed
Deal Type : Funding
Aphios Secures Grant for CCR5 Nanoparticles To Combat Alzheimer’s Disease
Details : The funding will support the company in developing anti-CCR5 nanoparticles for treating patients suffering from Alzheimer’s disease.
Product Name : Bryoid
Product Type : Undisclosed
Upfront Cash : Undisclosed
December 11, 2024
Lead Product(s) : Bryoid
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : National Institute on Aging
Deal Size : Undisclosed
Deal Type : Funding

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Lead Product(s) : APH-0812,Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aphios Granted US Patent For Combination HIV Latency Nanoparticles Towards an HIV Cure
Details : APH-0812, a combination therapy consisting of PKC agonists with or without HDAC inhibitors, is designed to reactivate latent HIV reservoirs so that HIV can be eliminated by antiviral therapy and eradicated from the body.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
February 08, 2022
Lead Product(s) : APH-0812,Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bryoid
Therapeutic Area : Neurology
Study Phase : Undisclosed
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aphios Granted Chinese Patent for Novel Bryoid to Treat Alzheimer’s Disease
Details : Bryoid, Bryostatin-23, is a highly potent nanomolar activator of α-secretase activity in neuroblastoma cell models, being effective than the canonical Bryostatin-1 at increasing activity of all protein kinase C isoforms, particularly the novel PKC isofo...
Product Name : Bryoid
Product Type : Undisclosed
Upfront Cash : Inapplicable
November 10, 2021
Lead Product(s) : Bryoid
Therapeutic Area : Neurology
Highest Development Status : Undisclosed
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Bryostatin-1,Tretinoin
Therapeutic Area : Neurology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Aphios Granted US Patent for Combination Therapeutic to Treat Neurodegenerative Diseases
Details : The combination therapeutic consists of biodegradable polymer nanospheres co-encapsulating a Bryoid and a Retinoid to improve synergistically alpha-secretase (α-secretase) production and reduce -amyloid plaque generation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 01, 2020
Lead Product(s) : Bryostatin-1,Tretinoin
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : APH-1501
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction
Details : APH-1501 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Behavior, Addictive.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 23, 2019
Lead Product(s) : APH-1501
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease
Details : APH-1105 is a drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Dementia.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 16, 2019
