Company profile for Valo Therapeutics

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About

VALO TX is a developer of novel cancer immunotherapies that are projected to transform the lives of millions of cancer patients. Our unique approach to immunotherapy in cancer, based on an oncolytic virus non-covalently combined with tumor-specific peptides, delivers a highly immunogenic and rapidly adaptable tumor vaccination platform.

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CONTACT DETAILS

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Country
Country
United Kingdom
Address
Address
62 Harpes Road, Oxford, UK. OX2 7QL
Telephone
Telephone
+44 20 3920 7649‬
youtube
YouTube

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NEWS #PharmaBuzz

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ValoTx Appoints Marcella Origgi as CEO
ValoTx Appoints Marcella Origgi as CEO

09 Apr 2025

// GLOBENEWSWIRE

https://www.globenewswire.com/news-release/2025/04/09/3058128/0/en/ValoTx-Appoints-Marcella-Origgi-from-Johnson-Johnson-Innovation-as-CEO.html

GLOBENEWSWIRE
09 Apr 2025

https://www.globenewswire.com/news-release/2025/03/10/3039464/0/en/Valo-Therapeutics-announces-EUR-19m-of-investment-funding-and-expanded-clinical-trials.html

GLOBENEWSWIRE
10 Mar 2025

https://www.globenewswire.com/news-release/2024/11/06/2975782/18623/en/Lisata-Therapeutics-and-Valo-Therapeutics-Announce-Preclinical-Research-Collaboration.html

GLOBENEWSWIRE
06 Nov 2024

https://www.globenewswire.com//news-release/2023/11/29/2787495/0/en/Valo-Therapeutics-Announces-Regulatory-Approval-to-Expand-Phase-I-Immuno-oncology-Trial-into-Sarcoma.html

GLOBENEWSWIRE
29 Nov 2023

https://www.globenewswire.com//news-release/2023/10/10/2757151/0/en/Valo-Therapeutics-Announces-Acquisition-of-Bruker-Corporation-s-Latest-Mass-Spectrometer-Platform-for-Tumor-Antigen-Identification-with-ValoTx-s-PeptiCHIP-Technology.html

GLOBENEWSWIRE
10 Oct 2023

http://www.pharmabiz.com/NewsDetails.aspx?aid=159719&sid=2

PHARMABIZ
15 Jun 2023

Drugs in Development

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Details:

The financing will enable Valo to expand and complete the Phase 1B clinical study of PeptiCRAd-1, the company's lead tumour antigen-coated oncolytic virus candidate.


Lead Product(s): PeptiCRAd-1,Cyclophosphamide,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Indaco Venture Partners

Deal Size: $20.6 million Upfront Cash: Undisclosed

Deal Type: Financing March 10, 2025

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Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : The financing will enable Valo to expand and complete the Phase 1B clinical study of PeptiCRAd-1, the company's lead tumour antigen-coated oncolytic virus candidate.

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Undisclosed

March 10, 2025

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Details:

The collaboration aims to investigate the benefits of combining Lisata's, LSTA1 (certepetide), with ValoTx's platform technology, PeptiCRAd, and a checkpoint inhibitor in a melanoma mouse model.


Lead Product(s): Certepetide,Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Peptide, Unconjugated

Sponsor: Lisata Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration November 06, 2024

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02

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : The collaboration aims to investigate the benefits of combining Lisata's, LSTA1 (certepetide), with ValoTx's platform technology, PeptiCRAd, and a checkpoint inhibitor in a melanoma mouse model.

Product Name : Undisclosed

Product Type : Peptide, Unconjugated

Upfront Cash : Undisclosed

November 06, 2024

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Details:

PeptiCRAd-1 is an intratumoral injection vaccine, being investigated for Synovial Sarcoma treatment, in combination with Pembrolizumab and Cyclophosphamide.


Lead Product(s): PeptiCRAd-1,Cyclophosphamide,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable November 29, 2023

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03

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : PeptiCRAd-1 is an intratumoral injection vaccine, being investigated for Synovial Sarcoma treatment, in combination with Pembrolizumab and Cyclophosphamide.

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Inapplicable

November 29, 2023

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Details:

The collaboration aims to investigate immune responses to PeptiCRAd-1 in its Phase 1 clinical study. PeptiCRAd-1 is the company’s lead product made up of its virus VALO-D102 coated with MAGE-A3 and NY-ESO-1 peptides.


Lead Product(s): PeptiCRAd-1,Cyclophosphamide,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Texcell

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration June 13, 2023

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04

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : The collaboration aims to investigate immune responses to PeptiCRAd-1 in its Phase 1 clinical study. PeptiCRAd-1 is the company’s lead product made up of its virus VALO-D102 coated with MAGE-A3 and NY-ESO-1 peptides.

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Undisclosed

June 13, 2023

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Details:

PeptiCRAd-1 is a cancer immunotherapy drug candidate designed to stimulate systemic tumor-directed cytotoxic T-cell responses in cancer patients. Combined with its local immune modulation effect at the tumor site, it has the potential to deliver synergistic clinical outcomes.


Lead Product(s): PeptiCRAd-1,Cyclophosphamide,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 23, 2023

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05

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : PeptiCRAd-1 is a cancer immunotherapy drug candidate designed to stimulate systemic tumor-directed cytotoxic T-cell responses in cancer patients. Combined with its local immune modulation effect at the tumor site, it has the potential to deliver synergis...

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Inapplicable

May 23, 2023

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Details:

PeptiCRAd-1 is a cancer immunotherapy drug candidate designed to stimulate systemic tumor-directed cytotoxic T-cell responses in cancer patients. Combined with its local immune modulation effect at the tumor site, it has the potential to deliver synergistic clinical outcomes.


Lead Product(s): PeptiCRAd-1,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 16, 2023

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06

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : PeptiCRAd-1 is a cancer immunotherapy drug candidate designed to stimulate systemic tumor-directed cytotoxic T-cell responses in cancer patients. Combined with its local immune modulation effect at the tumor site, it has the potential to deliver synergis...

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Inapplicable

February 16, 2023

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Details:

VALO-D102 is a fundamental component of the company’s proprietary PeptiCRAd (peptide-coated Conditionally Replicating Adenovirus) immuno-oncology platform. PeptiCRAd combines two cancer immunotherapy approaches: an oncolytic Adenovirus and a peptide vaccine.


Lead Product(s): PeptiCRAd-1

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: DiscoveryProduct Type: Vaccine

Sponsor: Exothera

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement January 11, 2023

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07

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : VALO-D102 is a fundamental component of the company’s proprietary PeptiCRAd (peptide-coated Conditionally Replicating Adenovirus) immuno-oncology platform. PeptiCRAd combines two cancer immunotherapy approaches: an oncolytic Adenovirus and a peptide va...

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Undisclosed

January 11, 2023

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Details:

PeptiCRAd-1 is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Melanoma.


Lead Product(s): PeptiCRAd-1,Cyclophosphamide,Pembrolizumab

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Vaccine

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable August 08, 2022

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08

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : PeptiCRAd-1 is a Vaccine drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Melanoma.

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Inapplicable

August 08, 2022

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Details:

PeptiCHIP enables to identify antigens faster than existing technologies and, in combination with lead delivery platform, PeptiCRAd (unique way of combining two clinically proven cancer immunotherapy approaches: an oncolytic Adenovirus and a peptide vaccine).


Lead Product(s): PeptiCRAd

Therapeutic Area: Oncology Brand Name: PeptiCRAd

Study Phase: DiscoveryProduct Type: Vaccine

Recipient: University of Helsinki

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition July 26, 2022

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09

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : PeptiCHIP enables to identify antigens faster than existing technologies and, in combination with lead delivery platform, PeptiCRAd (unique way of combining two clinically proven cancer immunotherapy approaches: an oncolytic Adenovirus and a peptide vacc...

Product Name : PeptiCRAd

Product Type : Vaccine

Upfront Cash : Undisclosed

July 26, 2022

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Details:

In immunological tumour animal models, pre-immunisation with tetanus specific peptides significantly enhanced responses following subsequent vaccination with tumour-peptide coated oncolytic Adenoviruses; ValoTx’s PeptiCRAd technology, in combination with anti-PD1.


Lead Product(s): PeptiCRAd-1

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Vaccine

Recipient: University of Helsinki

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition January 06, 2022

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10

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Valo Therapeutics

United Kingdom
arrow
BioProcess International US West
Not Confirmed

Details : In immunological tumour animal models, pre-immunisation with tetanus specific peptides significantly enhanced responses following subsequent vaccination with tumour-peptide coated oncolytic Adenoviruses; ValoTx’s PeptiCRAd technology, in combination wi...

Product Name : Undisclosed

Product Type : Vaccine

Upfront Cash : Undisclosed

January 06, 2022

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