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    Company profile for Sagimet Biosciences

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    About

    We are focused on blocking fatty acid synthase (FASN) a key regulator of lipid synthesis, FASN activity is increased in certain diseases such as in the liver of patients with NASH and in certain tumor types. We believe that FASN provides an intervention point for clinical benefit. Our lead product candidate, TVB-2640, is an oral, highly potent, selective and reversible, first-in-class inhibitor of FASN in clinical developme...
    We are focused on blocking fatty acid synthase (FASN) a key regulator of lipid synthesis, FASN activity is increased in certain diseases such as in the liver of patients with NASH and in certain tumor types. We believe that FASN provides an intervention point for clinical benefit. Our lead product candidate, TVB-2640, is an oral, highly potent, selective and reversible, first-in-class inhibitor of FASN in clinical development. Phase 1 clinical studies showed that TVB-2640 inhibits de novo lipogenesis in cancer patients and reduces liver fat synthesis in people with characteristics of metabolic syndrome.

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    CONTACT DETAILS

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    Sagimet BiosciencesUnited_States_of_America Flag
    Country
    Country
    U.S.A
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    Address
    155 Bovet Road, Suite 303 San Mateo, CA 94402
    Telephone
    Telephone
    +1 650.561.8600
    Client Email
    Email
    enquiries@pharmacompass.com
    Client Website
    Website
    https://sagimet.com/
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    Twitter

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    NEWS #PharmaBuzz

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    Sagimet Bio To Participate In 2 Upcoming Investor Conferences
    Sagimet Bio To Participate In 2 Upcoming Investor Conferences

    05 Feb 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/02/05/3232821/0/en/Sagimet-Biosciences-Announces-Participation-in-Two-Upcoming-Investor-Conferences.html

    GLOBENEWSWIRE
    05 Feb 2026
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    Sagimet Announces Positive 52-Wk Denifanstat Data in Severe MASH
    Sagimet Announces Positive 52-Wk Denifanstat Data in Severe MASH

    02 Feb 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/02/02/3230125/0/en/Sagimet-Announces-Positive-52-Week-Data-from-License-Partner-Ascletis-Open-Label-Phase-3-Clinical-Trial-Evaluating-the-Long-Term-Safety-of-ASC40-Denifanstat-Tablets-in-Patients-wit.html

    GLOBENEWSWIRE
    02 Feb 2026
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    Sagimet Biosciences Presents Poster At MASH-TAG 2026 Conference
    Sagimet Biosciences Presents Poster At MASH-TAG 2026 Conference

    08 Jan 2026

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2026/01/08/3215214/0/en/Sagimet-Biosciences-Announces-Poster-Presentation-at-the-10th-Annual-MASH-TAG-2026-Conference.html

    GLOBENEWSWIRE
    08 Jan 2026
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    TAPI and Sagimet Biosciences Announce Global License Agreement
    TAPI and Sagimet Biosciences Announce Global License Agreement

    19 Dec 2025

    // PRESS RELEASE

    https://tapi.com/knowledge-center/tapi-and-sagimet-biosciences-announce-global-license-agreement-for-innovative-forms-of-resmetirom-api-for-sagimets-fixed-dose-combination-program/

    PRESS RELEASE
    19 Dec 2025
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    Sagimet Biosciences Reports Positive Phase 1 Results in PK Trial
    Sagimet Biosciences Reports Positive Phase 1 Results in PK Trial

    18 Dec 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/12/18/3207571/0/en/Sagimet-Biosciences-Announces-Positive-Results-from-the-Phase-1-PK-Clinical-Trial-of-Denifanstat-and-Resmetirom-Combination.html

    GLOBENEWSWIRE
    18 Dec 2025
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    Ascletis Accepts Denifanstat NDA For Moderate To Severe Acne
    Ascletis Accepts Denifanstat NDA For Moderate To Severe Acne

    10 Dec 2025

    // GLOBENEWSWIRE

    https://www.globenewswire.com/news-release/2025/12/10/3203051/0/en/Sagimet-s-License-Partner-Ascletis-Announced-Acceptance-of-New-Drug-Application-for-Denifanstat-for-the-Treatment-of-Moderate-to-Severe-Acne-by-China-s-National-Medical-Products-Ad.html

    GLOBENEWSWIRE
    10 Dec 2025
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