With recent advances in sequencing technologies and bioinformatic capabilities, we have uncovered a large family of viruses that constitute the majority of the human commensal virome. These encapsidated viruses remain as episomal DNA elements once inside the cell and have coevolved with us over millennia, joining us in an intimate symbiotic relationship. The virome, an intrinsic element of biology—present in virtually every ...
With recent advances in sequencing technologies and bioinformatic capabilities, we have uncovered a large family of viruses that constitute the majority of the human commensal virome. These encapsidated viruses remain as episomal DNA elements once inside the cell and have coevolved with us over millennia, joining us in an intimate symbiotic relationship. The virome, an intrinsic element of biology—present in virtually every person and a diverse array of tissues—represents an opportunity to create a gene therapy platform applicable to many diseases.
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