Just as an instrument can be tuned to create an entirely different sound, RNA transcripts can also be tuned in a multitude of ways, extending far beyond simply splicing out non-coding introns. Development of new molecular tools and the advent of next-generation, multi-omic disease datasets has given us better insight into RNA’s vast intricacies and unveiled new, exciting insights into how RNA is processed and dysregulated af...
Just as an instrument can be tuned to create an entirely different sound, RNA transcripts can also be tuned in a multitude of ways, extending far beyond simply splicing out non-coding introns. Development of new molecular tools and the advent of next-generation, multi-omic disease datasets has given us better insight into RNA’s vast intricacies and unveiled new, exciting insights into how RNA is processed and dysregulated after transcription. By unlocking these tools and controlling RNA processing we can target the drivers of disease at their origin, affording rich therapeutic opportunities.
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