Company profile for Crescent Biopharma

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About

Crescent Biopharma aims to become a world-leading oncology company, delivering next-generation therapies for cancer patients. Its pipeline features a PD-1 x VEGF bispecific antibody and novel antibody-drug conjugates. By leveraging multiple modalities and validated targets, Crescent focuses on advancing transformative treatments either as monotherapies or in combination to address a variety of solid tumors.

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CONTACT DETAILS

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Country
Country
U.S.A
Address
Address
Boston, Massachusetts
Telephone
Telephone
Linkedin
Linkedin
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YouTube
Twitter
Twitter

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NEWS #PharmaBuzz

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https://www.globenewswire.com/news-release/2026/03/27/3264092/0/en/Crescent-Biopharma-Announces-Grants-of-Inducement-Awards.html

GLOBENEWSWIRE
27 Mar 2026

https://www.globenewswire.com/news-release/2026/03/06/3251321/0/en/Crescent-Biopharma-Announces-Grants-of-Inducement-Awards.html

GLOBENEWSWIRE
06 Mar 2026

https://www.globenewswire.com/news-release/2026/02/23/3242526/0/en/Crescent-Biopharma-to-Present-at-March-Investor-Conferences.html

GLOBENEWSWIRE
23 Feb 2026

https://www.globenewswire.com/news-release/2026/02/19/3240981/0/en/Crescent-Biopharma-Announces-Grants-of-Inducement-Awards.html

GLOBENEWSWIRE
19 Feb 2026

https://www.globenewswire.com/news-release/2026/02/18/3240098/0/en/Crescent-Biopharma-Announces-First-Patient-Dosed-in-ASCEND-Phase-1-2-Clinical-Trial-of-CR-001-for-the-Treatment-of-Advanced-Solid-Tumors.html

GLOBENEWSWIRE
18 Feb 2026

https://www.globenewswire.com/news-release/2026/02/05/3232891/0/en/Crescent-Biopharma-to-Present-at-the-Guggenheim-Emerging-Outlook-Biotech-Summit-2026.html

GLOBENEWSWIRE
05 Feb 2026

Drugs in Development

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Details:

CR-001 is a large molecule drug, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of neoplasms.


Lead Product(s): CR-001

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 13, 2026

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01

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : CR-001 is a large molecule drug, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of neoplasms.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

January 13, 2026

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Details:

CR-001, an unconjugated antibody targeting PD-1 and VEGF, shows promise in treating advanced solid tumors.


Lead Product(s): CR-001

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: IND EnablingProduct Type: Antibody, Unconjugated

Sponsor: Sichuan Kelun-Biotech Biopharmaceutical

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 05, 2026

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02

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : CR-001, an unconjugated antibody targeting PD-1 and VEGF, shows promise in treating advanced solid tumors.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

January 05, 2026

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Details:

SKB105, an antibody-drug conjugate targeting ITGB6, shows promise in treating advanced solid tumors.


Lead Product(s): SKB105

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: IND EnablingProduct Type: Antibody-drug Conjugate

Recipient: Sichuan Kelun-Biotech Biopharmaceutical

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable January 05, 2026

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03

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : SKB105, an antibody-drug conjugate targeting ITGB6, shows promise in treating advanced solid tumors.

Product Name : Undisclosed

Product Type : Antibody-drug Conjugate

Upfront Cash : Inapplicable

January 05, 2026

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Details:

In a private placement deal, CR-004, an antibody-drug conjugate, secures funding to advance its development in an undisclosed target area.


Lead Product(s): CR-004,Undisclosed

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Antibody-drug Conjugate

Sponsor: Forbion

Deal Size: $185.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement December 04, 2025

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04

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : In a private placement deal, CR-004, an antibody-drug conjugate, secures funding to advance its development in an undisclosed target area.

Product Name : Undisclosed

Product Type : Antibody-drug Conjugate

Upfront Cash : Undisclosed

December 04, 2025

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Details:

Through the merger, the combined company will operate under the name Crescent Biopharma and will advance its pipeline activities, including CR-001, which is being evaluated for the treatment of NSCLC.


Lead Product(s): CR-001

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Miscellaneous

Sponsor: Crescent Biopharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger June 16, 2025

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05

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : Through the merger, the combined company will operate under the name Crescent Biopharma and will advance its pipeline activities, including CR-001, which is being evaluated for the treatment of NSCLC.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

June 16, 2025

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Details:

The proceeds from the placement will used to advance the clinical development of CR-001, which is being evaluated for the treatment of Non-Small Cell Lung Cancer.


Lead Product(s): CR-001

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Miscellaneous

Sponsor: Fairmount

Deal Size: $200.0 million Upfront Cash: Undisclosed

Deal Type: Private Placement June 16, 2025

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06

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Lead Product(s) : CR-001

Therapeutic Area : Oncology

Highest Development Status : Preclinical

Partner/Sponsor/Collaborator : Fairmount

Deal Size : $200.0 million

Deal Type : Private Placement

Details : The proceeds from the placement will used to advance the clinical development of CR-001, which is being evaluated for the treatment of Non-Small Cell Lung Cancer.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

June 16, 2025

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Details:

The combined company will advance Crescent’s portfolio of precision-engineered biologics including its lead program CR-001, a tetravalent PD-1 x VEGF bispecific antibody.


Lead Product(s): CR-001

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: PreclinicalProduct Type: Miscellaneous

Sponsor: Crescent Biopharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Merger October 29, 2024

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07

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : The combined company will advance Crescent’s portfolio of precision-engineered biologics including its lead program CR-001, a tetravalent PD-1 x VEGF bispecific antibody.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Undisclosed

October 29, 2024

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Details:

GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with newly diagnosed acute myeloid leukemia (AML) who are 60 years or older.


Lead Product(s): Uproleselan,Etoposide,Mitoxantrone

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: The Division of Cancer Treatment and Diagnosis

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable October 29, 2024

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08

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : GMI-1271 (uproleselan) is a E-selectin inhibitor, which is being evaluated to treat adults with newly diagnosed acute myeloid leukemia (AML) who are 60 years or older.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

October 29, 2024

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Details:

GMI-1271 (uproleselan) is a first-in-class E-selectin antagonist, which is under phase 3 development for the treatment of of adults with relapsed or refractory acute myeloid leukemia.


Lead Product(s): Uproleselan,Etoposide,Mitoxantrone

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable June 04, 2024

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09

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : GMI-1271 (uproleselan) is a first-in-class E-selectin antagonist, which is under phase 3 development for the treatment of of adults with relapsed or refractory acute myeloid leukemia.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

June 04, 2024

blank

Details:

GMI-1271 (uproleselan) is an investigational, first-in-class E-selectin antagonist, which is under phase 3 clinical development for adults with relapsed or refractory acute myeloid leukemia.


Lead Product(s): Uproleselan,Etoposide,Mitoxantrone

Therapeutic Area: Oncology Brand Name: Undisclosed

Study Phase: Phase IIIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable May 06, 2024

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10

Nutri Ingredients Summit
Not Confirmed
Nutri Ingredients Summit
Not Confirmed

Details : GMI-1271 (uproleselan) is an investigational, first-in-class E-selectin antagonist, which is under phase 3 clinical development for adults with relapsed or refractory acute myeloid leukemia.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

May 06, 2024

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