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Looking for Bosentan? Find Granulation used in Bosentan to address drug delivery challenges on PharmaCompass.

Excipients
Granulation
Bosentan

Capsule
Emulsion
Gel
Granule / Pellet
Orodispersible Tablet
Softgels
Solution
Tablet
Topical Film
Transdermal patches

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients, & custom-made solutions to our customers.

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Inke S.A: APIs manufacturing plant.

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AbbVie CDMO has been working with global companies to develop, manufacture & scale biopharmaceutical products.

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With Fermion, start the journey of your innovative API.

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Bosentan

ACCESS ALL DATA, CHEMISTRY

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

57 API Suppliers, 20 USDMF, 9 JDMF, 20 EU WC, 6 KDMF, 12 NDC API, 33 Listed Suppliers, $ API Reference Price

57 API Suppliers
20 USDMF
9 JDMF
20 EU WC
6 KDMF
12 NDC API
33 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

INTERMEDIATES

5 Intermediate Suppliers

5 Intermediate Suppliers

FINISHED DOSAGE FORMULATIONS

150 FDF Dossiers, 27 FDA Orange Book, 44 Europe, 10 Canada, 52 Australia, 17 Listed Dossiers

150 FDF Dossiers
27 FDA Orange Book
44 Europe
10 Canada
52 Australia
17 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

TABLET;ORAL - 125MG, TABLET;ORAL - 62.5MG

TABLET;ORAL - 125MG
TABLET;ORAL - 62.5MG

RELATED EXCIPIENT COMPANIES

1 Evonik, 2 Rochem International Inc, 5 SPI Pharma, 5 DKSH, 3 Faran Shimi Pharmaceutical, 2 Boai NKY Pharmaceuticals Ltd, 6 Gangwal Healthcare, 1 Capital Farma, 1 ACG Worldwide, 1 Aeon Procare, 8 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 1 BASF, 11 Corel Pharma Chem, 4 DFE Pharma, 7 Gangwal Chemicals, 5 Ideal Cures Pvt Ltd, 4 Ingredion Pharma Solutions, 15 Kerry, 4 Kima Chemical, 6 Lonza Capsugel, 8 Microlex e.U, 1 Novo Excipients, 2 Pharmatrans-Sanaq, 3 Pluviaendo, 4 Prachin Chemical, 1 Qianhao Chemical (Hebei) Co., Ltd, 1 Qualicaps, 18 Roquette, 7 Seppic, 5 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 11 Sigachi Industries, 4 Silverline Chemicals, 3 The Dow Chemical Company, 1 Ulanqab Kema New Material, 4 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

44 Coating Systems & Additives, 39 Fillers, Diluents & Binders, 26 Disintegrants & Superdisintegrants, 22 Controlled & Modified Release, 17 Thickeners and Stabilizers, 15 Direct Compression, 13 Lubricants & Glidants, 13 Granulation, 12 Taste Masking, 11 Film Formers & Plasticizers, 9 Co-Processed Excipients, 7 Chewable & Orodispersible Aids, 5 Rheology Modifiers, 5 Empty Capsules, 4 Coloring Agents, 4 Emulsifying Agents, 4 Vegetarian Capsules, 4 API Stability Enhancers, 3 Solubilizers, 1 Topical

44 Coating Systems & Additives
39 Fillers, Diluents & Binders
26 Disintegrants & Superdisintegrants
22 Controlled & Modified Release
17 Thickeners and Stabilizers
15 Direct Compression
13 Lubricants & Glidants
13 Granulation
12 Taste Masking
11 Film Formers & Plasticizers
9 Co-Processed Excipients
7 Chewable & Orodispersible Aids
5 Rheology Modifiers
5 Empty Capsules
4 Coloring Agents
4 Emulsifying Agents
4 Vegetarian Capsules
4 API Stability Enhancers
3 Solubilizers
1 Topical

DIGITAL CONTENT

28 News #PharmaBuzz

28 News #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 29 Regulatory FDF Prices, 4 Annual Reports

2 US Medicaid Prescriptions
29 Regulatory FDF Prices
4 Annual Reports

MARKET PLACE

9 APIs

9 APIs

PATENTS & EXCLUSIVITIES

2 US Patents, 2 Health Canada Patents

2 US Patents
2 Health Canada Patents

REF. STANDARDS & IMPURITIES

3 USP, 6 Others

3 USP
6 Others

ANALYTICAL

2 BioAnalytical Methods

2 BioAnalytical Methods

$ API Ref.Price (USD/KG) : 2,818 Xls

Filters

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Bosentan

Filters

FILTER :

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20 All

01 3Corel Pharma Chem

02 1Ingredion Pharma Solutions

03 1Kima Chemical

04 1Microlex e.U

05 4Pharmatrans-Sanaq

06 1Prachin Chemical

07 4Sigachi Industries

08 5The Dow Chemical Company

filter Capability Reset all filters

20 All

01 5Capsule

02 1Granule / Pellet

03 1Orodispersible Tablet

04 13Tablet

filter Country Reset all filters

20 All

01 1Austria

02 1China

03 8India

04 4Switzerland

05 6U.S.A

01

Sigachi Industries

AMWC Asia-TDAC

Not Confirmed

Sigachi Industries

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : AceCel

Application : Direct Compression, Fillers, Diluents & Binders, Granulation

Excipient Details : AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Category : Direct Compression, Fillers, Diluents & Binders, Granulation

Brand : ACECEL

Applications : AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

02

Prachin Chemical

AMWC Asia-TDAC

Not Confirmed

Prachin Chemical

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : PARCROS

Application : Direct Compression, Disintegrants & Superdisintegrants, Granulation

Excipient Details : Croscarmellose sodium, a cellulose-based super disintegrant, provides excellent results in tablet disintegration. It is used in both wet granulation and direct compression.

Pharmacopoeia Ref : IP/BP/USP/EP

Technical Specs : NA

Ingredient(s) : Croscarmellose Sodium

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Croscarmellose Sodium

Dosage Form : Tablet

Category : Direct Compression, Disintegrants & Superdisintegrants, Granulation

Brand : PARCROS

Applications : Croscarmellose sodium, a cellulose-based super disintegrant, provides excellent results in tablet disintegration. It is used in both wet granulation and direct compression.

Pharmacopoeia Ref : IP/BP/USP/EP

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

03

The Dow Chemical Company

AMWC Asia-TDAC

Not Confirmed

The Dow Chemical Company

U.S.A

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Capsule, Orodispersible Tablet, Tablet

Grade :

Brand Name : ETHOCEL™

Application : Controlled & Modified Release, Granulation, Taste Masking

Excipient Details : Moisture barrier, Multi particulates, Dry powder layering, Granulation, Hot melt extrusion, Taste Masking, Controlled / Modified Release

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : EthylCellulose

Dosage Form : Capsule, Orodispersible Tablet, Tablet

Grade :

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Ingredient(s) : EthylCellulose

Dosage Form : Capsule, Orodispersible Tablet, Tablet

Category : Controlled & Modified Release, Granulation, Taste Masking

Brand : ETHOCEL™

Applications : Moisture barrier, Multi particulates, Dry powder layering, Granulation, Hot melt extrusion, Taste Masking, Controlled / Modified Release

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

04

Sigachi Industries

AMWC Asia-TDAC

Not Confirmed

Sigachi Industries

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : HiCel

Application : Direct Compression, Fillers, Diluents & Binders, Granulation

Excipient Details : HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Category : Direct Compression, Fillers, Diluents & Binders, Granulation

Brand : HICEL

Applications : HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

05

Pharmatrans-Sanaq

AMWC Asia-TDAC

Not Confirmed

Pharmatrans-Sanaq

Switzerland

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Capsule, Tablet

Grade : Oral

Brand Name : SSG SANAQ

Application : Disintegrants & Superdisintegrants, Granulation, Lubricants & Glidants

Excipient Details : Sodium Starch Glycolate is used as a lubricant and disintegrant in the formulation of tablets, capsules and granules. The tablets mainly are produced by direct tableting and wet granulation.

Pharmacopoeia Ref : EP./USP.NF

Technical Specs : NA

Ingredient(s) : Sodium Starch Glycolate

Dosage Form : Capsule, Tablet

Grade : Oral

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Ingredient(s) : Sodium Starch Glycolate

Dosage Form : Capsule, Tablet

Category : Disintegrants & Superdisintegrants, Granulation, Lubricants & Glidants

Brand : SSG SANAQ

Applications : Sodium Starch Glycolate is used as a lubricant and disintegrant in the formulation of tablets, capsules and granules. The tablets mainly are produced by direct tableting and wet granulation.

Pharmacopoeia Ref : EP./USP.NF

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

06

Ingredion Pharma Solutions

UNI-PURE WG 220

AMWC Asia-TDAC

Not Confirmed

Ingredion Pharma Solutions

U.S.A

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Uni-Pure Wg 220

Application : Fillers, Diluents & Binders, Granulation

Excipient Details : Fully Pregel Starch Corn is used as a binder in wet granulation in the manufacturing of tablets.

Pharmacopoeia Ref : USP/NF, Ph. Eur., Ch. P.

Technical Specs : NA

Ingredient(s) : Corn Starch, Pregelatinized, Corn Starch

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Corn Starch, Pregelatinized, Corn Starch

Dosage Form : Tablet

Category : Fillers, Diluents & Binders, Granulation

Brand : UNI-PURE WG 220

Applications : Fully Pregel Starch Corn is used as a binder in wet granulation in the manufacturing of tablets.

Pharmacopoeia Ref : USP/NF, Ph. Eur., Ch. P.

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

07

Pharmatrans-Sanaq

AMWC Asia-TDAC

Not Confirmed

Pharmatrans-Sanaq

Switzerland

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Capsule, Tablet

Grade : Oral

Brand Name : MCC SANAQ

Application : Fillers, Diluents & Binders, Granulation

Excipient Details : Microcrystalline Cellulose is mainly used as filling, binding and blasting material for tablets (direct tableting), as well as for dry and wet granulation and as filling material for hard gelatin capsules.

Pharmacopoeia Ref : EP./USP.NF

Technical Specs : NA

Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Capsule, Tablet

Grade : Oral

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Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Capsule, Tablet

Category : Fillers, Diluents & Binders, Granulation

Brand : MCC SANAQ

Applications : Microcrystalline Cellulose is mainly used as filling, binding and blasting material for tablets (direct tableting), as well as for dry and wet granulation and as filling material for hard gelatin capsules.

Pharmacopoeia Ref : EP./USP.NF

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

08

The Dow Chemical Company

AMWC Asia-TDAC

Not Confirmed

The Dow Chemical Company

U.S.A

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet, Capsule

Grade :

Brand Name : METHOCEL™

Application : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

Excipient Details : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Hydroxypropyl Methylcellulose

Dosage Form : Tablet, Capsule

Grade :

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Ingredient(s) : Hydroxypropyl Methylcellulose

Dosage Form : Tablet, Capsule

Category : API Stability Enhancers, Coating Systems & Additives, Controlled & Modified Release, Direct Compression, Granulation, Rheology Modifiers, Vegetarian Capsules

Brand : METHOCEL™

Applications : Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Not Available

Excipients Web Link

Digital Content

09

Kima Chemical

HYDROXYPROPYL METHYL CELLULOSE (60E3)

AMWC Asia-TDAC

Not Confirmed

Kima Chemical

China

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Hydroxypropyl Methyl Cellul...

Application : Coating Systems & Additives, Fillers, Diluents & Binders, Granulation

Excipient Details : Hydroxypropyl Methyl Cellulose (60E3) is used as a binding, coating, and granulating agent for the production of tablets.

Pharmacopoeia Ref : NA

Technical Specs : NA

Ingredient(s) : Hydroxypropyl Methyl Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Hydroxypropyl Methyl Cellulose

Dosage Form : Tablet

Category : Coating Systems & Additives, Fillers, Diluents & Binders, Granulation

Brand : HYDROXYPROPYL METHYL CELLULOSE (60E3)

Applications : Hydroxypropyl Methyl Cellulose (60E3) is used as a binding, coating, and granulating agent for the production of tablets.

Pharmacopoeia Ref : NA

Technical Specs : NA

Grade : Oral

Excipients Web Link

Digital Content

10

Sigachi Industries

AMWC Asia-TDAC

Not Confirmed

Sigachi Industries

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Hilose

Application : Disintegrants & Superdisintegrants, Granulation

Excipient Details : It is used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets & Granules Formulations. In tablet formulations, it is used in both direct compression & wet granulation processes.

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Croscarmellose Sodium

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Croscarmellose Sodium

Dosage Form : Tablet

Category : Disintegrants & Superdisintegrants, Granulation

Brand : HILOSE

Applications : It is used in oral pharmaceutical formulations as a super disintegrant for Capsules, Tablets & Granules Formulations. In tablet formulations, it is used in both direct compression & wet granulation processes.

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

11

Sigachi Industries

AMWC Asia-TDAC

Not Confirmed

Sigachi Industries

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : HiCellac

Application : Direct Compression, Granulation

Excipient Details : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

Pharmacopoeia Ref :

Technical Specs :

Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Lactose Monohydrate, Microcrystalline Cellulose

Dosage Form : Tablet

Category : Direct Compression, Granulation

Brand : HICELLAC

Applications : HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.

Pharmacopoeia Ref : Not Available

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

12

Microlex e.U

MICROLEX® MCC 101

AMWC Asia-TDAC

Not Confirmed

Microlex e.U

Austria

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Tablet

Grade : Oral

Brand Name : Microlex® MCC 101

Application : Direct Compression, Granulation

Excipient Details : Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs :

Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Grade : Oral

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Ingredient(s) : Microcrystalline Cellulose

Dosage Form : Tablet

Category : Direct Compression, Granulation

Brand : MICROLEX® MCC 101

Applications : Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.

Pharmacopoeia Ref : Monograph- USP/NF, JP/JPE

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

Digital Content

13

Corel Pharma Chem

NUTRACOAT EC25D

AMWC Asia-TDAC

Not Confirmed

Corel Pharma Chem

India

AMWC Asia-TDAC

Not Confirmed

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Dosage Form : Capsule, Granule / Pellet, Tablet

Grade : Oral

Brand Name : Nutracoat EC25D

Application : Controlled & Modified Release, Fillers, Diluents & Binders, Film Formers & Plasticizers, Granulation, Taste Masking

Excipient Details : Sustained Release, Taste Masking, Moisture Barrier, Binder in Wet Granulation

Pharmacopoeia Ref : USP/NF: Ethyl cellulose disper...

Technical Specs :

Ingredient(s) : EthylCellulose

Dosage Form : Capsule, Granule / Pellet, Tablet

Grade : Oral

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Ingredient(s) : EthylCellulose

Dosage Form : Capsule, Granule / Pellet, Tablet

Category : Controlled & Modified Release, Fillers, Diluents & Binders, Film Formers & Plasticizers, Granulation, Taste Masking

Brand : NUTRACOAT EC25D

Applications : Sustained Release, Taste Masking, Moisture Barrier, Binder in Wet Granulation

Pharmacopoeia Ref : USP/NF: Ethyl cellulose dispersion Type B

Technical Specs : Not Available

Grade : Oral

Excipients Web Link

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