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    List of chemical intermediates, fine chemicals supplied/manufactured by Guangdong Raffles Pharmatech Co Ltd

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    Guangdong Raffles PharmaTech Co Ltd

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    01 ((2-Bromoethoxy)methyl)benzene (1)

    02 (+)-(3aR,4R,5r,6aS)-Hexahydro-5 -hydroxy-4-[(1 E,3R)-3-hydroxy-5-phenyl-1-pentenyl]-2H-cyclopenta [b]furan-2-one (1)

    03 (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(methylene)sulfinyl)cyclopropane-1-carboxamide (5)

    04 (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)sulfonyl)cyclopropane-1-carboxamide hydrochloride (5)

    05 (1R,2R)-2-(allyloxy)cyclopentan-1-ol (5)

    06 (2-oxoheptyl)-phosphonicacidimethylester (1)

    07 (33R,35S,91 R,92R,5S,E)-5-(tert-b utyl)-N-((1 R,2R)-2-(difluoromethy l)-1-(((1-methylcyclopropyl)sulfony l)carbamoyl)cyclopropyl)-14,14-dif luoro-4,7-dioxo-2,8,10-trioxa-6-az a-1(2,3)-quinoxalina-3(3,1)-pyrroli dina-9(1,2)-cyclopentanacyclotetr adecaphan- (5)

    08 (33R,35S,91R,92R,5S,E)-5-(tert-butyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina -3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxylic acid (5)

    09 (3S,11aR)-6-methoxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3,2-d]pyrido[1,2-a]pyrazine-8-carboxylic acid (1)

    10 (3S,11aR)-N-(2,4-difluorobenzyl)-6-methoxy-3-methyl-5,7-dioxo-2,3,5,7,11,11a-hexahydrooxazolo[3, 2-d]pyrido[1,2-a]pyrazine-8-carboxamide (1)

    11 (3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxo-4-phenoxybut-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate (1)

    12 (3aR,4R,5R,6aS)-4-((E)-4,4-difluoro-3-oxooct-1-en-1-yl)-5-((tetrahydro-2H-pyran-2-yl)oxy)hexahydro-2H-cyclopenta[b]furan-2-one (1)

    13 (3aR,4R,5R,6aS)-4-((R)-3-hydroxy-5-phenylpentyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate (1)

    14 (3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4-phenoxy-1-butenyl]hexahydro-5-hydroxy-2H-cyclopenta[b]furan-2-one (1)

    15 (3aR,4R,5R,6aS)-5-(benzoyloxy)-4-[(1 E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-on (1)

    16 (3aR,4R,5R,6aS)-5-hydroxy-4-[(3 R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one (1)

    17 (4R,12aS)-7-Methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid (1)

    18 (4R,12aS)-N-(2,4-Difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxamide (1)

    19 (4S)-(3',4'-Dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one (2)

    20 (5R)-2-Oxazolidinone,5-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl) (1)

    21 (5Z)-7-[(1R)-3a,5a-Dihydroxy-2p-[(1E,3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentan-1a-yl]-5-heptenoic acid (1)

    22 (E)-N'-(1-cyclopropyl-3-(2-fluoro-4 -iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide (1)

    23 (R)-2-amino-1-(2,2-dimethyl-4H-benzo[d][1,3]dioxin-6-yl)ethanol (1)

    24 (R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one (1)

    25 (R)-N-(2-(8-(benzyloxy)-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethyl)-5,6-diethyl-2,3-dihydro-1H-inden-2-aminium benzoate (1)

    26 (S)-2-{[(((1R,2R)-2-(allyloxy)cyclopentyl)oxy)carbonyl]amino}-3,3-dimethylbutanoic acid (5)

    27 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2[(E)-(S)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid methyl ester (1)

    28 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid (1)

    29 1-(2,5-dimethoxyphenyl)propan-1-one (1)

    30 1-(6-Methylpyridin-3-yl)-2-[4-(methylthio)phenyl]ethanone (1)

    31 1-(6-methyl-3-pyridyl)-2-(4-(methylsulfonyl)-phenyl)ethanone (1)

    32 1-(tert-butyl)2-methyl(2S,4R)-4-((3-(1,1 -difluoroallyl)quinoxalin-2-yl)oxy)pyrrolidine-1,2-dicarboxylate (5)

    33 1-Methylcyclopropanesulfonamide (5)

    34 1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea (1)

    35 2'-hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid (1)

    36 2,2'-disulfanediylbis(N-methylbenzamide) (1)

    37 2,2,2-trimethylthioacetamide (1)

    38 2,3-dimethyl-2H-indazol-6-amine (1)

    39 2,3-dimethyl-2H-indazol-6-amine hydrochloride (1)

    40 2,3-dimethyl-6-Nitro-2H-indazole (1)

    41 2,6-dichloro-3,5-dimethoxyaniline (1)

    42 2-(1H-indazol-6-ylthio)-N-methyl-Benzamide (1)

    43 2-chloro-1,3-bis(dimentylamino)trimethinium hexafluorophosphate (1)

    44 2-chloro-3-(1,1 -difluoroallyl)quinoxaline (5)

    45 2-mercapto-N-methyl-Benzamide (1)

    46 2H-Cyclopenta[b]furan-2,5-diol, hexahydro-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-,(3aR,4R,5R,6aS)- (1)

    47 2H-Cyclopenta[b]furan-2,5-diol, hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-,(3aR,4R,5R,6aS)- (1)

    48 2H-Cyclopenta[b]furan-2,5-diol,4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-,(3aR,4R,5 R,6aS)- (1)

    49 3'-amino-2'-hydroxybiphenyl-3-carboxylic acid (1)

    50 3'-amino-2'-hydroxybiphenyl-3-carboxylic acid HCl (1)

    51 3,5-dimethoxyaniline (1)

    52 3-(1,1 -difluoroallyl)quinoxalin-2-ol (5)

    53 3-Iodo-6-nitro-1H-indazole (1)

    54 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione (1)

    55 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl 4-methylbenzenesulfonate (1)

    56 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione (1)

    57 3-methyl-1-(3,4-dimethylphenyl)-2-pyrazolin-5-one 2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one (1)

    58 3-methyl-6-nitro-indazole (1)

    59 4-methylsulphonylphenylacetic acid (1)

    60 4-methylthiophenylacetic acid (1)

    61 4H-1,3-Benzodioxin-6-Methanol,2,2-diMethyl-a-[[(phenylMethyl)amino]Methyl]-, (aR)- (1)

    62 5'-chloro-2'-hydroxy-3'-nitro-[1,1'-Biphenyl]-3-carboxylic acid (1)

    63 5'-chloro-2'-hydroxy-[1, 1'-Bipheny l]-3-carboxylic acid (1)

    64 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride (1)

    65 5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone (1)

    66 6-Iodo-1H-indazole (1)

    67 6-Iodo-3(E)-2-pyridin-2-yl-vinyl)-1-(tetrahydropyran-2-yl)-1H-indazole (1)

    68 6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole (1)

    69 6-amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)pyrimidine-2,4(1 H,3H)-dione (1)

    70 7-[2-(3,3-difluoro-4-phenoxybut-1-enyl)-3,5-dihydroxycyclopentyl]hept-5-enoic acid (1)

    71 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline (1)

    72 Benzene,2-[[2-[(6-broMohexyl)oxy]ethoxy]Methyl]-1,3-dichloro (1)

    73 Cyclopropanecarbothioamide (5)

    74 Cyclopropanesulfonamide (5)

    75 Dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate (1)

    76 Dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate (1)

    77 Dimethyl(2-oxo-3-phenoxypropyl) phosphonate (1)

    78 Dimethyl(2-oxo-4-phenylbutyl)phosphonate (1)

    79 Dimethyl[2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate (1)

    80 Diphenyl(quinuclidin-4-yl)methanol (1)

    81 Ethyl quinuclidine-4-carboxylate (1)

    82 Ethyl quinuclidine-4-carboxylate Hydrochloride (1)

    83 Hydroxyethylamyl (1)

    84 Latanoprost Lactone Diol (1)

    85 Methyl 3-((2,6-difluorophenyl)sulfonamido)-2-fluorobenzoate (1)

    86 Methyl 3-amino-2-fluorobenzoate (1)

    87 Methyl 6-methylnicotinate (1)

    88 Methyl(2S,4R)-1-((S)-2-(((((1 R,2R)-2-(allyloxy)cyclopentyl)oxy)carbonyl)amino)-3,3-dimethylbutanoyl)-4-[(3-(1,1 -difluoroallyl)quinoxalin-2-yl)oxy]pyrrolidine-2-carboxylate (5)

    89 Methyl(33R,35S,91R,92R,5S,E)-5-(tert-butyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxylate (5)

    90 N-(2-Chloropyrimidin-4-yl)-N-methyl-2,3-dimethyl-2H-indazol-6-amine (1)

    91 N-(3-(3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-ylamino)phenyl)acetamide (1)

    92 N-(tert-butyl)-3-chloropropane-1-sulfonamide (5)

    93 N-tert-butylcyclopropanesulfonamide (5)

    94 N-{3-[(2-chloro-4-pyrimidinyl)acetyl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide (1)

    95 N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide (1)

    96 [(3aR,4R,5R,6aS)-4-[(3S)-3-hydroxy-5-phenylpent-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta [b]furan-5-yl] benzoate (1)

    97 [1,1'-Biphenyl]-4-carboxylic acid (3aR,4R,5R,6aS)-hexahydro-2-oxo-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2H-cycl openta[b]furan-5-yl ester (1)

    98 [1,1'-Biphenyl]-4-carboxylic acid, (3aR,4R,5R,6aS)-hexahydro-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl ester (1)

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    01 Axitinib (6)

    02 Bimatoprost (6)

    03 Cabotegravir (2)

    04 Dabrafenib Mesylate (5)

    05 Dasotraline (1)

    06 Dinoprostone (1)

    07 Dolutegravir Sodium (5)

    08 Eltrombopag (6)

    09 Etoricoxib (6)

    10 Glecaprevir (16)

    11 Grazoprevir (16)

    12 Hydroxyethyl Starch (1)

    13 Indacaterol Maleate (5)

    14 Latanoprost (2)

    15 Lubiprostone (1)

    16 Methoxamine (3)

    17 Pazopanib Hydrochloride (6)

    18 Ruzasvir (16)

    19 Sertraline Hydrochloride (1)

    20 Simeprevir (16)

    21 Tafluprost (6)

    22 Trametinib (7)

    23 Travoprost (5)

    24 Umeclidinium Bromide (4)

    25 Vilanterol Trifenatate (4)

    26 Voxilaprevir (16)

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      ((2-Bromoethoxy)methyl)benzene

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      1462-37-9
      Umeclidinium Bromide
      Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
      Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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        (+)-(3aR,4R,5r,6aS)-Hexahydro-5 -hydroxy-4-[(1 E,3R)-3-hydroxy...

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        41639-74-1
        Bimatoprost
        Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
        Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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          (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(m...

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          Glecaprevir
          Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
          Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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            (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(m...

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            Grazoprevir
            Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
            Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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              (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(m...

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              Voxilaprevir
              Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
              Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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                (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(m...

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                Simeprevir
                Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
                Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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                  (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)-(m...

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                  1360997-58-5
                  Ruzasvir
                  Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
                  Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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                    (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)sul...

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                    1360828-80-3
                    Glecaprevir
                    Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
                    Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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                      (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)sul...

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                      Grazoprevir
                      Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
                      Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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                        (1R,2R)-1-amino-2-(difluoromethyl)-N-((1-methylcyclopropyl)sul...

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                        1360828-80-3
                        Voxilaprevir
                        Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, ...
                        Established in August 2011, Raffles PharmaTech is a high-tech enterprise that focus on development, manufacturing and sales of high-value added active pharmaceutical ingredients and intermediates. We are specialized in applying organic catalysts into the process development to lower cost, and to provide cost-effective product and service to customers. With our strong R&D capability and our proprietary organic catalysts, we provide low cost and high quality active pharmaceutical ingredients and intermediates to pharmaceutical companies. We also provide world standard process development, custom synthesis and manufacturing service.
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