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    Minzasolmin

    DEVELOPMENTS

    PharmaCompass
    Xls

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    2D Structure
    Also known as: 1802518-92-8, Minzasolmin [inn], 3n0435tg2d, Unii-3n0435tg2d, (r)-n-(1-(1h-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide, 5-thiazolecarboxamide, n-((1r)-1-(1h-indol-3-ylmethyl)pentyl)-2-(4-methyl-1-piperazinyl)-
    Molecular Formula
    C23H31N5OS
    Molecular Weight
    425.6  g/mol
    InChI Key
    GDFWCSZNQVAQGR-GOSISDBHSA-N
    FDA UNII
    3N0435TG2D
    Minzasolmin is under investigation in clinical trial NCT05543252 (An Extension Study to Evaluate the Long-term Efficacy, Safety and Tolerability of Minzasolmin (UCB0599) in Study Participants With Parkinson's Disease).
    1 2D Structure

    2D Structure

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N-[(2R)-1-(1H-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide
    2.1.2 InChI
    InChI=1S/C23H31N5OS/c1-3-4-7-18(14-17-15-24-20-9-6-5-8-19(17)20)26-22(29)21-16-25-23(30-21)28-12-10-27(2)11-13-28/h5-6,8-9,15-16,18,24H,3-4,7,10-14H2,1-2H3,(H,26,29)/t18-/m1/s1
    2.1.3 InChI Key
    GDFWCSZNQVAQGR-GOSISDBHSA-N
    2.2 Other Identifiers
    2.2.1 UNII
    3N0435TG2D
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 1802518-92-8

    2. Minzasolmin [inn]

    3. 3n0435tg2d

    4. Unii-3n0435tg2d

    5. (r)-n-(1-(1h-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide

    6. 5-thiazolecarboxamide, N-((1r)-1-(1h-indol-3-ylmethyl)pentyl)-2-(4-methyl-1-piperazinyl)-

    7. 5-thiazolecarboxamide, N-[(1r)-1-(1h-indol-3-ylmethyl)pentyl]-2-(4-methyl-1-piperazinyl)-

    8. N-((1r)-1-(1h-indol-3-ylmethyl)pentyl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide

    9. N-[(2r)-1-(1h-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide

    10. Minzasolmina

    11. Minzasolmine

    12. (r)-n-[1-(1h-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide

    13. N-[(1r)-1-(1h-indol-3-ylmethyl)pentyl]-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide

    14. Minzasolmin (usan/inn)

    15. Minzasolmin [usan]

    16. Dlx313

    17. Chembl5095072

    18. Schembl16973853

    19. Dlx-313

    20. Bdbm510823

    21. Glxc-26948

    22. Ex-a6318

    23. Ucb-0599

    24. Da-65474

    25. Hy-145580

    26. Us11078196, Ex. 28

    27. Cs-0376408

    28. D12796

    29. (r)-n-(1-(1h-indol-3-yl)hexan- 2-yl)-2-(4-methylpiperazin-1- Yl)thiazole-5-carboxamide

    30. N-[(1r)-1-(1h-indol-3-ylmethyl)pentyl]-2-(4-methyl-1-piperazinyl)-5-thiazolecarboxamide

    2.4 Create Date
    2016-02-23
    3 Chemical and Physical Properties
    Molecular Weight 425.6 g/mol
    Molecular Formula C23H31N5OS
    XLogP34.8
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count8
    Exact Mass Da
    Monoisotopic Mass Da
    Topological Polar Surface Area92.5
    Heavy Atom Count30
    Formal Charge0
    Complexity556
    Isotope Atom Count0
    Defined Atom Stereocenter Count1
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1